 Integrin alphaV
"Integrin alphaV" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing extracellular matrix proteins.
| Descriptor ID |
D039564
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| MeSH Number(s) |
D12.776.543.750.705.408.100.900
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| Concept/Terms |
Integrin alphaV- Integrin alphaV
- alphaV, Integrin
- alpha(V) Integrin
- Integrin alpha V
- alpha V, Integrin
- CD51 Antigens
- alphav Integrin
- Integrin, alphav
- Antigens, CD51
- CD51 Antigen
- Antigen, CD51
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Below are MeSH descriptors whose meaning is more general than "Integrin alphaV".
Below are MeSH descriptors whose meaning is more specific than "Integrin alphaV".
This graph shows the total number of publications written about "Integrin alphaV" by people in this website by year, and whether "Integrin alphaV" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin alphaV" by people in Profiles.
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Harlow DE, Saul KE, Komuro H, Macklin WB. Myelin Proteolipid Protein Complexes with av Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression. J Neurosci. 2015 Aug 26; 35(34):12018-32.
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Buchholz DE, Hikita ST, Rowland TJ, Friedrich AM, Hinman CR, Johnson LV, Clegg DO. Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells. 2009 Oct; 27(10):2427-34.
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Gudz TI, Komuro H, Macklin WB. Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex. J Neurosci. 2006 Mar 01; 26(9):2458-66.
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Chen X, Liu S, Hou Y, Tohme M, Park R, Bading JR, Conti PS. MicroPET imaging of breast cancer alphav-integrin expression with 64Cu-labeled dimeric RGD peptides. Mol Imaging Biol. 2004 Sep-Oct; 6(5):350-9.
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Chen X, Park R, Tohme M, Shahinian AH, Bading JR, Conti PS. MicroPET and autoradiographic imaging of breast cancer alpha v-integrin expression using 18F- and 64Cu-labeled RGD peptide. Bioconjug Chem. 2004 Jan-Feb; 15(1):41-9.
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Gudz TI, Schneider TE, Haas TA, Macklin WB. Myelin proteolipid protein forms a complex with integrins and may participate in integrin receptor signaling in oligodendrocytes. J Neurosci. 2002 Sep 01; 22(17):7398-407.
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Cripe TP, Dunphy EJ, Holub AD, Saini A, Vasi NH, Mahller YY, Collins MH, Snyder JD, Krasnykh V, Curiel DT, Wickham TJ, DeGregori J, Bergelson JM, Currier MA. Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells. Cancer Res. 2001 Apr 01; 61(7):2953-60.
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