Valinomycin
"Valinomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.
Descriptor ID |
D014634
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MeSH Number(s) |
D04.345.566.297.500 D12.644.641.297.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Valinomycin".
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This graph shows the total number of publications written about "Valinomycin" by people in this website by year, and whether "Valinomycin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Valinomycin" by people in Profiles.
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Zhang C, Lee S, Peng Y, Bunker E, Shen C, Giaime E, Shen J, Shen J, Zhou Z, Liu X. A chemical genetic approach to probe the function of PINK1 in regulating mitochondrial dynamics. Cell Res. 2015 Mar; 25(3):394-7.
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Duke RC, Witter RZ, Nash PB, Young JD, Ojcius DM. Cytolysis mediated by ionophores and pore-forming agents: role of intracellular calcium in apoptosis. FASEB J. 1994 Feb; 8(2):237-46.
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Restrepo D, Kimmich GA. Electrical potential dependence of Na+-sugar cotransport determined using TPP+ influx. Ann N Y Acad Sci. 1985; 456:77-9.
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Monroe JG, Cambier JC. B cell activation. III. B cell plasma membrane depolarization and hyper-Ia antigen expression induced by receptor immunoglobulin cross-linking are coupled. J Exp Med. 1983 Nov 01; 158(5):1589-99.
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