 Flavonols
"Flavonols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of 3-hydroxy-4-keto-FLAVONOIDS.
| Descriptor ID |
D044948
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| MeSH Number(s) |
D03.383.663.283.266.450.284 D03.633.100.150.266.450.284
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| Concept/Terms |
Flavonols- Flavonols
- 3-hydroxy-4-keto-Flavonoids
- 3 hydroxy 4 keto Flavonoids
- 2-Phenyl-3-Hydroxy-Benzopyran-4-Ones
- 2 Phenyl 3 Hydroxy Benzopyran 4 Ones
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Below are MeSH descriptors whose meaning is more general than "Flavonols".
Below are MeSH descriptors whose meaning is more specific than "Flavonols".
This graph shows the total number of publications written about "Flavonols" by people in this website by year, and whether "Flavonols" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 | | 2023 | 1 | 0 | 1 | | 2024 | 1 | 0 | 1 | | 2025 | 2 | 0 | 2 | | 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "Flavonols" by people in Profiles.
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Mahoney SA, Mazan-Mamczarz K, Tsitsipatis D, VanDongen NS, Henry-Smith C, Okereke AN, Munk R, Darvish S, Murray KO, De S, Gorospe M, Seals DR, Rossman MJ, Herman AB, Clayton ZS. Senolytic Treatment With Fisetin Reverses Age-Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12. Aging Cell. 2026 May; 25(5):e70500.
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Darrah MA, Mahoney SA, Venkatasubramanian R, VanDongen NS, Ludwig KR, Seals DR, Rossman MJ, Clayton ZS. Fisetin Supplementation Attenuates Premature Vascular Aging Induced by Doxorubicin via Suppression of Cellular Senescence and Mitochondrial Oxidative Stress. Aging Cell. 2026 May; 25(5):e70535.
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Wheeler LC, Larter M, Smith SD. MYB regulator of "colorless" flavonols underlies the evolution of red flowers in Iochroma (Solanaceae). G3 (Bethesda). 2025 12 10; 15(12).
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Murray KO, Mahoney SA, Ludwig KR, Miyamoto-Ditmon JH, VanDongen NS, Banskota N, Herman AB, Seals DR, Mankowski RT, Rossman MJ, Clayton ZS. Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches. Aging Cell. 2025 08; 24(8):e70114.
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Yadav M, Kandhari K, Mathan SV, Ali M, Singh RP. Fisetin induces G2/M phase arrest and caspase-mediated cleavage of p21Cip1 and p27Kip1 leading to apoptosis and tumor growth inhibition in HNSCC. Mol Carcinog. 2024 Sep; 63(9):1697-1711.
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Mahoney SA, Venkatasubramanian R, Darrah MA, Ludwig KR, VanDongen NS, Greenberg NT, Longtine AG, Hutton DA, Brunt VE, Campisi J, Melov S, Seals DR, Rossman MJ, Clayton ZS. Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence. Aging Cell. 2024 03; 23(3):e14060.
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Punia R, Raina K, Agarwal R, Singh RP. Acacetin enhances the therapeutic efficacy of doxorubicin in non-small-cell lung carcinoma cells. PLoS One. 2017; 12(8):e0182870.
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Lazarus LS, Esquer HJ, Benninghoff AD, Berreau LM. Sense and Release: A Thiol-Responsive Flavonol-Based Photonically Driven Carbon Monoxide-Releasing Molecule That Operates via a Multiple-Input AND Logic Gate. J Am Chem Soc. 2017 07 19; 139(28):9435-9438.
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Sabarwal A, Agarwal R, Singh RP. Fisetin inhibits cellular proliferation and induces mitochondria-dependent apoptosis in human gastric cancer cells. Mol Carcinog. 2017 02; 56(2):499-514.
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Bhat TA, Nambiar D, Pal A, Agarwal R, Singh RP. Fisetin inhibits various attributes of angiogenesis in vitro and in vivo--implications for angioprevention. Carcinogenesis. 2012 Feb; 33(2):385-93.
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