 Receptors, KIR2DL2
"Receptors, KIR2DL2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A KIR receptor that has specificity for HLA-C ANTIGENS. It is an inhibitory receptor that contains D1 and D2 extracellular immunoglobulin-like domains and a long cytoplasmic tail. It is similar in structure and function to the KIR2DL1 RECEPTORS and the KIR2DL3 RECEPTORS.
| Descriptor ID |
D054343
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| MeSH Number(s) |
D12.776.543.750.705.895.500.374
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| Concept/Terms |
Receptors, KIR2DL2- Receptors, KIR2DL2
- KIR2DL2 Receptors
- Killer Cell Immunoglobulin-like Receptor 2DL2
- Killer Cell Immunoglobulin like Receptor 2DL2
- Natural Killer-Associated Transcript 6
- Natural Killer Associated Transcript 6
- CD158b1 Antigens
- CD158b1 Antigen
- Antigen, CD158b1
- KIR2DL2 Receptor
- Receptor, KIR2DL2
- Antigens, CD158b1
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Below are MeSH descriptors whose meaning is more general than "Receptors, KIR2DL2".
Below are MeSH descriptors whose meaning is more specific than "Receptors, KIR2DL2".
This graph shows the total number of publications written about "Receptors, KIR2DL2" by people in this website by year, and whether "Receptors, KIR2DL2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, KIR2DL2" by people in Profiles.
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Ahn R, Vukcevic D, Motyer A, Nititham J, Squire DM, Hollenbach JA, Norman PJ, Ellinghaus E, Nair RP, Tsoi LC, Oksenberg J, Foerster J, Lieb W, Weidinger S, Franke A, Elder JT, Jorgenson E, Leslie S, Liao W. Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis. Front Immunol. 2021; 12:684326.
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Hilton HG, Blokhuis JH, Guethlein LA, Norman PJ, Parham P. Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C. J Immunol. 2017 03 01; 198(5):1961-1973.
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Hilton HG, Guethlein LA, Goyos A, Nemat-Gorgani N, Bushnell DA, Norman PJ, Parham P. Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes. J Immunol. 2015 Oct 01; 195(7):3160-70.
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Foley B, Cooley S, Verneris MR, Pitt M, Curtsinger J, Luo X, Lopez-Verg?s S, Lanier LL, Weisdorf D, Miller JS. Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function. Blood. 2012 Mar 15; 119(11):2665-74.
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Moesta AK, Norman PJ, Yawata M, Yawata N, Gleimer M, Parham P. Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3. J Immunol. 2008 Mar 15; 180(6):3969-79.
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Moodie SJ, Norman PJ, King AL, Fraser JS, Curtis D, Ellis HJ, Vaughan RW, Ciclitira PJ. Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters. Eur J Immunogenet. 2002 Aug; 29(4):287-91.
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