 Receptors, KIR2DL3
"Receptors, KIR2DL3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A KIR receptor that has specificity for HLA-C ANTIGEN. It is an inhibitory receptor that contains D1 and D2 extracellular immunoglobulin-like domains and a long cytoplasmic tail. It is similar in structure and function to the KIR2DL2 RECEPTORS and the KIR2DL3 RECEPTORS.
| Descriptor ID |
D054344
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| MeSH Number(s) |
D12.776.543.750.705.895.500.437
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| Concept/Terms |
Receptors, KIR2DL3- Receptors, KIR2DL3
- KIR2DL3 Receptors
- CD158b Antigen
- Antigen, CD158b
- Natural Killer-Associated Transcript 2
- Natural Killer Associated Transcript 2
- Antigens, CD158b
- CD158b Antigens
- Killer Cell Immunoglobulin-Like Receptor 2DL3
- Killer Cell Immunoglobulin Like Receptor 2DL3
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Below are MeSH descriptors whose meaning is more general than "Receptors, KIR2DL3".
Below are MeSH descriptors whose meaning is more specific than "Receptors, KIR2DL3".
This graph shows the total number of publications written about "Receptors, KIR2DL3" by people in this website by year, and whether "Receptors, KIR2DL3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, KIR2DL3" by people in Profiles.
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Hilton HG, Blokhuis JH, Guethlein LA, Norman PJ, Parham P. Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C. J Immunol. 2017 03 01; 198(5):1961-1973.
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He Y, Bunn PA, Zhou C, Chan D. KIR 2D (L1, L3, L4, S4) and KIR 3DL1 protein expression in non-small cell lung cancer. Oncotarget. 2016 Dec 13; 7(50):82104-82111.
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Hilton HG, Guethlein LA, Goyos A, Nemat-Gorgani N, Bushnell DA, Norman PJ, Parham P. Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes. J Immunol. 2015 Oct 01; 195(7):3160-70.
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Hilton HG, Vago L, Older Aguilar AM, Moesta AK, Graef T, Abi-Rached L, Norman PJ, Guethlein LA, Fleischhauer K, Parham P. Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3. J Immunol. 2012 Aug 01; 189(3):1418-30.
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Foley B, Cooley S, Verneris MR, Pitt M, Curtsinger J, Luo X, Lopez-Verg?s S, Lanier LL, Weisdorf D, Miller JS. Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function. Blood. 2012 Mar 15; 119(11):2665-74.
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Golden-Mason L, Bambha KM, Cheng L, Howell CD, Taylor MW, Clark PJ, Afdhal N, Rosen HR. Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C. Hepatology. 2011 Nov; 54(5):1559-69.
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Gendzekhadze K, Norman PJ, Abi-Rached L, Graef T, Moesta AK, Layrisse Z, Parham P. Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18692-7.
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Golden-Mason L. Natural killer cells play divergent roles in shaping the outcome of hepatitis C virus recurrence following liver transplantation. Liver Transpl. 2009 Apr; 15(4):357-9.
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McGrath E, Ryan EJ, Lynch L, Golden-Mason L, Mooney E, Eogan M, O'Herlihy C, O'Farrelly C. Changes in endometrial natural killer cell expression of CD94, CD158a and CD158b are associated with infertility. Am J Reprod Immunol. 2009 Apr; 61(4):265-76.
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Moesta AK, Norman PJ, Yawata M, Yawata N, Gleimer M, Parham P. Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3. J Immunol. 2008 Mar 15; 180(6):3969-79.
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