Glutamate-Ammonia Ligase
"Glutamate-Ammonia Ligase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of ATP, L-glutamate, and NH3 to ADP, orthophosphate, and L-glutamine. It also acts more slowly on 4-methylene-L-glutamate. (From Enzyme Nomenclature, 1992) EC 6.3.1.2.
Descriptor ID |
D005974
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MeSH Number(s) |
D08.811.464.259.200.600
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Concept/Terms |
Glutamate-Ammonia Ligase- Glutamate-Ammonia Ligase
- Glutamate Ammonia Ligase
- Ligase, Glutamate-Ammonia
- Glutamate Ammonia Ligase (ADP)
- Glutamine Synthetase
- Synthetase, Glutamine
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Below are MeSH descriptors whose meaning is more general than "Glutamate-Ammonia Ligase".
Below are MeSH descriptors whose meaning is more specific than "Glutamate-Ammonia Ligase".
This graph shows the total number of publications written about "Glutamate-Ammonia Ligase" by people in this website by year, and whether "Glutamate-Ammonia Ligase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 | 2004 | 1 | 0 | 1 | 2008 | 0 | 1 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glutamate-Ammonia Ligase" by people in Profiles.
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Vollbrecht PJ, Nesbitt KM, Addis VM, Boulnemour KM, Micheli DA, Smith KB, Sandoval DA, Kennedy RT, Ferrario CR. Differential regulation of nucleus accumbens glutamate and GABA in obesity-prone and obesity-resistant rats. J Neurochem. 2023 02; 164(4):499-511.
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Busanello EN, Fernandes CG, Martell RV, Lobato VG, Goodman S, Woontner M, de Souza DO, Wajner M. Disturbance of the glutamatergic system by glutaric acid in striatum and cerebral cortex of glutaryl-CoA dehydrogenase-deficient knockout mice: possible implications for the neuropathology of glutaric acidemia type I. J Neurol Sci. 2014 Nov 15; 346(1-2):260-7.
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Mongin AA, Hyzinski-Garc?a MC, Vincent MY, Keller RW. A simple method for measuring intracellular activities of glutamine synthetase and glutaminase in glial cells. Am J Physiol Cell Physiol. 2011 Oct; 301(4):C814-22.
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Hyzinski-Garc?a MC, Vincent MY, Haskew-Layton RE, Dohare P, Keller RW, Mongin AA. Hypo-osmotic swelling modifies glutamate-glutamine cycle in the cerebral cortex and in astrocyte cultures. J Neurochem. 2011 Jul; 118(1):140-52.
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Lenz LL, Huang WA, Zhou C, Li Z, Calendar R. Stable integration vector for nutrient broth-based selection of attenuated Listeria monocytogenes strains with recombinant antigen expression. Clin Vaccine Immunol. 2008 Sep; 15(9):1414-9.
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Galbraith MD, Giddens SR, Mahanty HK, Clark B. Role of glutamine synthetase in phenazine antibiotic production by Pantoea agglomerans Eh1087. Can J Microbiol. 2004 Oct; 50(10):877-81.
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Strong M, Mallick P, Pellegrini M, Thompson MJ, Eisenberg D. Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol. 2003; 4(9):R59.
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Bhandari B, Roesler WJ, DeLisio KD, Klemm DJ, Ross NS, Miller RE. A functional promoter flanks an intronless glutamine synthetase gene. J Biol Chem. 1991 Apr 25; 266(12):7784-92.
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Rothstein JD, Tabakoff B. Regulation of neurotransmitter aspartate metabolism by glial glutamine synthetase. J Neurochem. 1986 Jun; 46(6):1923-8.
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Rothstein JD, Tabakoff B. Glial and neuronal glutamate transport following glutamine synthetase inhibition. Biochem Pharmacol. 1985 Jan 01; 34(1):73-9.
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