 Foscarnet
"Foscarnet" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
| Descriptor ID |
D017245
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| MeSH Number(s) |
D02.241.081.018.677.250 D02.705.429.875.500
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| Concept/Terms |
Foscarnet Sodium- Foscarnet Sodium
- Sodium, Foscarnet
- Foscarnet Trisodium Salt
- Trisodium Salt, Foscarnet
- Foscarnet Sodium Hexahydrate
- Hexahydrate, Foscarnet Sodium
- Sodium Hexahydrate, Foscarnet
- Trisodium Phosphonoformate
- Phosphonoformate, Trisodium
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Below are MeSH descriptors whose meaning is more general than "Foscarnet".
Below are MeSH descriptors whose meaning is more specific than "Foscarnet".
This graph shows the total number of publications written about "Foscarnet" by people in this website by year, and whether "Foscarnet" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Foscarnet" by people in Profiles.
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Kumar P, Caruthers MH. DNA Analogues Modified at the Nonlinking Positions of Phosphorus. Acc Chem Res. 2020 10 20; 53(10):2152-2166.
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Vashishtha AK, Kuchta RD. Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA. Biochemistry. 2016 Feb 23; 55(7):1168-77.
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Nadlonek NA, Lee JH, Weyant MJ, Meng X, Fullerton DA. ox-LDL induces PiT-1 expression in human aortic valve interstitial cells. J Surg Res. 2013 Sep; 184(1):6-9.
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Chou S, Marousek G, Li S, Weinberg A. Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. J Clin Virol. 2008 Sep; 43(1):107-9.
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Chou S, Marousek GI, Van Wechel LC, Li S, Weinberg A. Growth and drug resistance phenotypes resulting from cytomegalovirus DNA polymerase region III mutations observed in clinical specimens. Antimicrob Agents Chemother. 2007 Nov; 51(11):4160-2.
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Scott GM, Weinberg A, Rawlinson WD, Chou S. Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates. Antimicrob Agents Chemother. 2007 Jan; 51(1):89-94.
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Yamada CM, Dellinger DJ, Caruthers MH. Synthesis and biochemical evaluation of phosphonoformate oligodeoxyribonucleotides. J Am Chem Soc. 2006 Apr 19; 128(15):5251-61.
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Springer KL, Chou S, Li S, Giller RH, Quinones R, Shira JE, Weinberg A. How evolution of mutations conferring drug resistance affects viral dynamics and clinical outcomes of cytomegalovirus-infected hematopoietic cell transplant recipients. J Clin Microbiol. 2005 Jan; 43(1):208-13.
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Levin MJ, Dahl KM, Weinberg A, Giller R, Patel A, Krause PR. Development of resistance to acyclovir during chronic infection with the Oka vaccine strain of varicella-zoster virus, in an immunosuppressed child. J Infect Dis. 2003 Oct 01; 188(7):954-9.
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Weinberg A, Jabs DA, Chou S, Martin BK, Lurain NS, Forman MS, Crumpacker C. Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. J Infect Dis. 2003 Mar 01; 187(5):777-84.
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