 Coagulase
"Coagulase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
| Descriptor ID |
D003030
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| MeSH Number(s) |
D08.811.277.656.300.174 D12.776.097.181
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| Concept/Terms |
Staphylococcal Clumping Factor- Staphylococcal Clumping Factor
- Clumping Factor, Staphylococcal
- Factor, Staphylococcal Clumping
- Clumping Factor (Staphylococcal)
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Below are MeSH descriptors whose meaning is more general than "Coagulase".
Below are MeSH descriptors whose meaning is more specific than "Coagulase".
This graph shows the total number of publications written about "Coagulase" by people in this website by year, and whether "Coagulase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 1 | 2 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Coagulase" by people in Profiles.
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Crosby HA, Kwiecinski JM, Horswill AR. In Vitro Assay for Quantifying Clumping of Staphylococcus aureus. Methods Mol Biol. 2021; 2341:31-36.
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Haivas CD, Teitelbaum I. Eradication of Repeated Episodes of Coagulase-Negative Staphylococcus Peritonitis: a Multipronged Approach. Perit Dial Int. 2019 Nov-Dec; 39(6):568-570.
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Williams MR, Costa SK, Zaramela LS, Khalil S, Todd DA, Winter HL, Sanford JA, O'Neill AM, Liggins MC, Nakatsuji T, Cech NB, Cheung AL, Zengler K, Horswill AR, Gallo RL. Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis. Sci Transl Med. 2019 05 01; 11(490).
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Trivedi U, Madsen JS, Everett J, Fell C, Russel J, Haaber J, Crosby HA, Horswill AR, Burm?lle M, Rumbaugh KP, S?rensen SJ. Staphylococcus aureus coagulases are exploitable yet stable public goods in clinically relevant conditions. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):E11771-E11779.
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Holland TL, Raad I, Boucher HW, Anderson DJ, Cosgrove SE, Aycock PS, Baddley JW, Chaftari AM, Chow SC, Chu VH, Carugati M, Cook P, Corey GR, Crowley AL, Daly J, Gu J, Hachem R, Horton J, Jenkins TC, Levine D, Miro JM, Pericas JM, Riska P, Rubin Z, Rupp ME, Schrank J, Sims M, Wray D, Zervos M, Fowler VG. Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial. JAMA. 2018 09 25; 320(12):1249-1258.
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Farnsworth CW, Schott EM, Jensen SE, Zukoski J, Benvie AM, Refaai MA, Kates SL, Schwarz EM, Zuscik MJ, Gill SR, Mooney RA. Adaptive Upregulation of Clumping Factor A (ClfA) by Staphylococcus aureus in the Obese, Type 2 Diabetic Host Mediates Increased Virulence. Infect Immun. 2017 06; 85(6).
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Kwiecinski J, Jin T, Josefsson E. Surface proteins of Staphylococcus aureus play an important role in experimental skin infection. APMIS. 2014 Dec; 122(12):1240-50.
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