Mammalian orthoreovirus 3
"Mammalian orthoreovirus 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotype of ORTHOREOVIRUS, MAMMALIAN causing serious pathology in laboratory rodents, characterized by diarrhea, oily coat, jaundice, and multiple organ involvement.
Descriptor ID |
D012089
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MeSH Number(s) |
B04.820.630.590.550.700
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mammalian orthoreovirus 3".
Below are MeSH descriptors whose meaning is more specific than "Mammalian orthoreovirus 3".
This graph shows the total number of publications written about "Mammalian orthoreovirus 3" by people in this website by year, and whether "Mammalian orthoreovirus 3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 | 1995 | 1 | 0 | 1 | 1996 | 1 | 0 | 1 | 1997 | 2 | 0 | 2 | 2001 | 1 | 0 | 1 | 2002 | 2 | 0 | 2 | 2004 | 2 | 0 | 2 | 2005 | 3 | 1 | 4 | 2007 | 2 | 0 | 2 | 2008 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2012 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2014 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mammalian orthoreovirus 3" by people in Profiles.
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Bonney S, Seitz S, Ryan CA, Jones KL, Clarke P, Tyler KL, Siegenthaler JA. Gamma Interferon Alters Junctional Integrity via Rho Kinase, Resulting in Blood-Brain Barrier Leakage in Experimental Viral Encephalitis. mBio. 2019 08 06; 10(4).
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Villalona-Calero MA, Lam E, Otterson GA, Zhao W, Timmons M, Subramaniam D, Hade EM, Gill GM, Coffey M, Selvaggi G, Bertino E, Chao B, Knopp MV. Oncolytic reovirus in combination with chemotherapy in metastatic or recurrent non-small cell lung cancer patients with KRAS-activated tumors. Cancer. 2016 Mar 15; 122(6):875-83.
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Clarke P, Leser JS, Bowen RA, Tyler KL. Virus-induced transcriptional changes in the brain include the differential expression of genes associated with interferon, apoptosis, interleukin 17 receptor A, and glutamate signaling as well as flavivirus-specific upregulation of tRNA synthetases. mBio. 2014 Mar 11; 5(2):e00902-14.
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Dionne KR, Zhuang Y, Leser JS, Tyler KL, Clarke P. Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis. J Virol. 2013 Mar; 87(6):3447-60.
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Schittone SA, Dionne KR, Tyler KL, Clarke P. Activation of innate immune responses in the central nervous system during reovirus myelitis. J Virol. 2012 Aug; 86(15):8107-18.
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Clarke P, Beckham JD, Leser JS, Hoyt CC, Tyler KL. Fas-mediated apoptotic signaling in the mouse brain following reovirus infection. J Virol. 2009 Jun; 83(12):6161-70.
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Goody RJ, Schittone SA, Tyler KL. Experimental reovirus-induced acute flaccid paralysis and spinal motor neuron cell death. J Neuropathol Exp Neurol. 2008 Mar; 67(3):231-9.
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Beckham JD, Goody RJ, Clarke P, Bonny C, Tyler KL. Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase. J Virol. 2007 Jul; 81(13):6984-92.
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Clarke P, Tyler KL. Down-regulation of cFLIP following reovirus infection sensitizes human ovarian cancer cells to TRAIL-induced apoptosis. Apoptosis. 2007 Jan; 12(1):211-23.
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Goody RJ, Hoyt CC, Tyler KL. Reovirus infection of the CNS enhances iNOS expression in areas of virus-induced injury. Exp Neurol. 2005 Oct; 195(2):379-90.
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