T-Cell Antigen Receptor Specificity
"T-Cell Antigen Receptor Specificity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The property of the T-CELL RECEPTOR which enables it to react with some antigens and not others. The specificity is derived from the structure of the receptor's variable region which has the ability to recognize certain antigens in conjunction with the MAJOR HISTOCOMPATIBILITY COMPLEX molecule.
Descriptor ID |
D037182
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MeSH Number(s) |
G12.450.900
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Concept/Terms |
T-Cell Antigen Receptor Specificity- T-Cell Antigen Receptor Specificity
- T Cell Antigen Receptor Specificity
- T-Cell Receptor Specificity
- Specificity, T-Cell Receptor
- T Cell Receptor Specificity
T-Cell Specificity- T-Cell Specificity
- Specificity, T-Cell
- T Cell Specificity
- T-Cell Immunologic Specificity
- Immunologic Specificity, T-Cell
- Specificity, T-Cell Immunologic
- T Cell Immunologic Specificity
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Below are MeSH descriptors whose meaning is more general than "T-Cell Antigen Receptor Specificity".
Below are MeSH descriptors whose meaning is more specific than "T-Cell Antigen Receptor Specificity".
This graph shows the total number of publications written about "T-Cell Antigen Receptor Specificity" by people in this website by year, and whether "T-Cell Antigen Receptor Specificity" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 0 | 1 | 2003 | 1 | 0 | 1 | 2004 | 0 | 2 | 2 | 2005 | 0 | 2 | 2 | 2006 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2009 | 0 | 2 | 2 | 2010 | 0 | 1 | 1 | 2011 | 1 | 1 | 2 | 2012 | 0 | 2 | 2 | 2014 | 0 | 3 | 3 | 2015 | 1 | 1 | 2 | 2016 | 1 | 3 | 4 | 2017 | 1 | 1 | 2 | 2019 | 0 | 3 | 3 | 2020 | 0 | 2 | 2 | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "T-Cell Antigen Receptor Specificity" by people in Profiles.
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Rosenberg AM, Ayres CM, Medina-Cucurella AV, Whitehead TA, Baker BM. Enhanced T cell receptor specificity through framework engineering. Front Immunol. 2024; 15:1345368.
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Tsitsiklis A, Bangs DJ, Lutes LK, Chan SW, Geiger KM, Modzelewski AJ, Labarta-Bajo L, Wang Y, Zuniga EI, Dai S, Robey EA. An Unusual MHC Molecule Generates Protective CD8+ T Cell Responses to Chronic Infection. Front Immunol. 2020; 11:1464.
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Sachs A, Moore E, Kosaloglu-Yalcin Z, Peters B, Sidney J, Rosenberg SA, Robbins PF, Sette A. Impact of Cysteine Residues on MHC Binding Predictions and Recognition by Tumor-Reactive T Cells. J Immunol. 2020 07 15; 205(2):539-549.
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Ramachandran I, Lowther DE, Dryer-Minnerly R, Wang R, Fayngerts S, Nunez D, Betts G, Bath N, Tipping AJ, Melchiori L, Navenot JM, Glod J, Mackall CL, D'Angelo SP, Araujo DM, Chow WA, Demetri GD, Druta M, Van Tine BA, Grupp SA, Abdul Razak AR, Wilky B, Iyengar M, Trivedi T, Winkle EV, Chagin K, Amado R, Binder GK, Basu S. Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma. J Immunother Cancer. 2019 10 24; 7(1):276.
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Tovar Salazar A, McKhann A, Chen H, Bosch RJ, Weinberg A. Immune Correlates of Herpes Zoster in People Living with HIV on Effective Antiretroviral Therapy. AIDS Res Hum Retroviruses. 2019 10; 35(10):890-895.
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Lindestam Arlehamn CS, Pham J, Alcalay RN, Frazier A, Shorr E, Carpenter C, Sidney J, Dhanwani R, Agin-Liebes J, Garretti F, Amara AW, Standaert DG, Phillips EJ, Mallal SA, Peters B, Sulzer D, Sette A. Widespread Tau-Specific CD4 T Cell Reactivity in the General Population. J Immunol. 2019 07 01; 203(1):84-92.
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Lu YC, Zheng Z, Robbins PF, Tran E, Prickett TD, Gartner JJ, Li YF, Ray S, Franco Z, Bliskovsky V, Fitzgerald PC, Rosenberg SA. An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors. Mol Ther. 2018 02 07; 26(2):379-389.
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Van Rhijn I, Iwany SK, Fodran P, Cheng TY, Gapin L, Minnaard AJ, Moody DB. CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails. Eur J Immunol. 2017 09; 47(9):1525-1534.
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Prickett TD, Crystal JS, Cohen CJ, Pasetto A, Parkhurst MR, Gartner JJ, Yao X, Wang R, Gros A, Li YF, El-Gamil M, Trebska-McGowan K, Rosenberg SA, Robbins PF. Durable Complete Response from Metastatic Melanoma after Transfer of Autologous T Cells Recognizing 10 Mutated Tumor Antigens. Cancer Immunol Res. 2016 08; 4(8):669-78.
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Yao X, Lu YC, Parker LL, Li YF, El-Gamil M, Black MA, Xu H, Feldman SA, van der Bruggen P, Rosenberg SA, Robbins PF. Isolation and Characterization of an HLA-DPB1*04: 01-restricted MAGE-A3 T-Cell Receptor for Cancer Immunotherapy. J Immunother. 2016 06; 39(5):191-201.
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