Transcription Factor TFIIIA
"Transcription Factor TFIIIA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of several general transcription factors that are specific for RNA POLYMERASE III. It is a zinc finger (ZINC FINGERS) protein and is required for transcription of 5S ribosomal genes.
Descriptor ID |
D035582
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MeSH Number(s) |
D12.776.260.775.937.249 D12.776.930.930.937.249
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Concept/Terms |
Transcription Factor TFIIIA- Transcription Factor TFIIIA
- Transcription Factor IIIA
- GTF3A Protein
- TFIIIA
- 5S Gene-Specific Transcription Factor
- 5S Gene Specific Transcription Factor
- 5S RNA Gene Transcription Factor
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor TFIIIA".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor TFIIIA".
This graph shows the total number of publications written about "Transcription Factor TFIIIA" by people in this website by year, and whether "Transcription Factor TFIIIA" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 2 | 2 | 1998 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor TFIIIA" by people in Profiles.
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Foster MP, Wuttke DS, Clemens KR, Jahnke W, Radhakrishnan I, Tennant L, Reymond M, Chung J, Wright PE. Chemical shift as a probe of molecular interfaces: NMR studies of DNA binding by the three amino-terminal zinc finger domains from transcription factor IIIA. J Biomol NMR. 1998 Jul; 12(1):51-71.
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Wuttke DS, Foster MP, Case DA, Gottesfeld JM, Wright PE. Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity. J Mol Biol. 1997 Oct 17; 273(1):183-206.
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Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE. Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA. Nat Struct Biol. 1997 Aug; 4(8):605-8.
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Churchill ME, Tullius TD, Klug A. Mode of interaction of the zinc finger protein TFIIIA with a 5S RNA gene of Xenopus. Proc Natl Acad Sci U S A. 1990 Jul; 87(14):5528-32.
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Vrana KE, Churchill ME, Tullius TD, Brown DD. Mapping functional regions of transcription factor TFIIIA. Mol Cell Biol. 1988 Apr; 8(4):1684-96.
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