 Retinoblastoma-Binding Protein 1
"Retinoblastoma-Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed regulatory protein that contains a retinoblastoma protein binding domain and an AT-rich interactive domain. The protein may play a role in recruiting HISTONE DEACETYLASES to the site of RETINOBLASTOMA PROTEIN-containing transcriptional repressor complexes.
| Descriptor ID |
D056465
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| MeSH Number(s) |
D12.644.360.024.328.100 D12.776.157.057.158.100 D12.776.476.024.420.100 D12.776.660.769.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinoblastoma-Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma-Binding Protein 1".
This graph shows the total number of publications written about "Retinoblastoma-Binding Protein 1" by people in this website by year, and whether "Retinoblastoma-Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 4 | 4 | | 1996 | 0 | 5 | 5 | | 1997 | 0 | 5 | 5 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinoblastoma-Binding Protein 1" by people in Profiles.
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Smith DS, Leone G, DeGregori J, Ahmed MN, Qumsiyeh MB, Nevins JR. Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway. Cell Growth Differ. 2000 Dec; 11(12):625-33.
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Zhu JW, DeRyckere D, Li FX, Wan YY, DeGregori J. A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection. Cell Growth Differ. 1999 Dec; 10(12):829-38.
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Leone G, DeGregori J, Jakoi L, Cook JG, Nevins JR. Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase. Proc Natl Acad Sci U S A. 1999 Jun 08; 96(12):6626-31.
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Yan Z, DeGregori J, Shohet R, Leone G, Stillman B, Nevins JR, Williams RS. Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3603-8.
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Kowalik TF, DeGregori J, Leone G, Jakoi L, Nevins JR. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ. 1998 Feb; 9(2):113-8.
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Nevins JR, Leone G, DeGregori J, Jakoi L. Role of the Rb/E2F pathway in cell growth control. J Cell Physiol. 1997 Nov; 173(2):233-6.
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DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci U S A. 1997 Jul 08; 94(14):7245-50.
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Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature. 1997 May 22; 387(6631):422-6.
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Fry CJ, Slansky JE, Farnham PJ. Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain. Mol Cell Biol. 1997 Apr; 17(4):1966-76.
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Nevins JR, DeGregori J, Jakoi L, Leone G. Functional analysis of E2F transcription factor. Methods Enzymol. 1997; 283:205-19.
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