 Gemfibrozil
"Gemfibrozil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lipid-regulating agent that lowers elevated serum lipids primarily by decreasing serum triglycerides with a variable reduction in total cholesterol.
| Descriptor ID |
D015248
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| MeSH Number(s) |
D02.241.081.114.968.500.750 D02.241.081.944.509.350 D02.355.726.305.750 D02.455.426.559.389.657.654.305.750 D10.251.400.895.593.350
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Gemfibrozil".
Below are MeSH descriptors whose meaning is more specific than "Gemfibrozil".
This graph shows the total number of publications written about "Gemfibrozil" by people in this website by year, and whether "Gemfibrozil" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2008 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gemfibrozil" by people in Profiles.
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Wiggins BS, Saseen JJ, Morris PB. Gemfibrozil in Combination with Statins-Is It Really Contraindicated? Curr Atheroscler Rep. 2016 Apr; 18(4):18.
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Aquilante CL, Kosmiski LA, Bourne DW, Bushman LR, Daily EB, Hammond KP, Hopley CW, Kadam RS, Kanack AT, Kompella UB, Le M, Predhomme JA, Rower JE, Sidhom MS. Impact of the CYP2C8 *3 polymorphism on the drug-drug interaction between gemfibrozil and pioglitazone. Br J Clin Pharmacol. 2013 Jan; 75(1):217-26.
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Alford JC, Saseen JJ, Allen RR, Nair KV. Persistent use of against-label statin-fibrate combinations from 2003-2009 despite United States Food and Drug Administration dose restrictions. Pharmacotherapy. 2012 Jul; 32(7):623-30.
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Rower JE, Bushman LR, Hammond KP, Kadam RS, Aquilante CL. Validation of an LC/MS method for the determination of gemfibrozil in human plasma and its application to a pharmacokinetic study. Biomed Chromatogr. 2010 Dec; 24(12):1300-8.
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Belknap SM, Moore H, Lanzotti SA, Yarnold PR, Getz M, Deitrick DL, Peterson A, Akeson J, Maurer T, Soltysik RC, Storm GA, Brooks I. Application of software design principles and debugging methods to an analgesia prescription reduces risk of severe injury from medical use of opioids. Clin Pharmacol Ther. 2008 Sep; 84(3):385-92.
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Freeman SR, Drake AL, Heilig LF, Graber M, McNealy K, Schilling LM, Dellavalle RP. Statins, fibrates, and melanoma risk: a systematic review and meta-analysis. J Natl Cancer Inst. 2006 Nov 01; 98(21):1538-46.
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Saseen J, Tweed E, Crawford P. Clinical inquiries. What are effective medication combinations for dyslipidemia? J Fam Pract. 2006 Jan; 55(1):70-2.
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Dellavalle RP, Nicholas MK, Schilling LM. Melanoma chemoprevention: a role for statins or fibrates? Am J Ther. 2003 May-Jun; 10(3):203-10.
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Hokanson JE, Austin MA, Zambon A, Brunzell JD. Plasma triglyceride and LDL heterogeneity in familial combined hyperlipidemia. Arterioscler Thromb. 1993 Mar; 13(3):427-34.
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