 Sirtuin 1
"Sirtuin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
| Descriptor ID |
D056564
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| MeSH Number(s) |
D08.811.277.087.520.200.650.100 D12.776.476.900.100
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| Concept/Terms |
Sirtuin 1- Sirtuin 1
- Silent Mating Type Information Regulation 2 Homolog 1
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Below are MeSH descriptors whose meaning is more general than "Sirtuin 1".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 1".
This graph shows the total number of publications written about "Sirtuin 1" by people in this website by year, and whether "Sirtuin 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 3 | 3 | | 2015 | 3 | 1 | 4 | | 2016 | 1 | 3 | 4 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sirtuin 1" by people in Profiles.
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Bo?kovic M, ?ivkovic M, Koricanac G, Stani?ic J, Zec M, Krga I, Stankovic A. Walnut Supplementation Restores the SIRT1-FoxO3a-MnSOD/Catalase Axis in the Heart, Promotes an Anti-Inflammatory Fatty Acid Profile in Plasma, and Lowers Blood Pressure on Fructose-Rich Diet. Oxid Med Cell Longev. 2021; 2021:5543025.
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Leblond A, Pezet S, Cauvet A, Casas C, Pires Da Silva J, Herv? R, Clavel G, Dumas S, Cohen-Kaminsky S, Bessis N, Semerano L, Lemaire C, Allanore Y, Avouac J. Implication of the deacetylase sirtuin-1 on synovial angiogenesis and persistence of experimental arthritis. Ann Rheum Dis. 2020 07; 79(7):891-900.
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Lee SE, Koh H, Joo DJ, Nedumaran B, Jeon HJ, Park CS, Harris RA, Kim YD. Induction of SIRT1 by melatonin improves alcohol-mediated oxidative liver injury by disrupting the CRBN-YY1-CYP2E1 signaling pathway. J Pineal Res. 2020 Apr; 68(3):e12638.
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Pires Da Silva J, Monceaux K, Guilbert A, Gressette M, Piquereau J, Novotova M, Ventura-Clapier R, Garnier A, Lemaire C. SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy. Cells. 2020 02 12; 9(2).
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Esmaeili S, Motamedrad M, Hemmati M, Mehrpour O, Khorashadizadeh M. Prevention of kidney cell damage in hyperglycaemia condition by adiponectin. Cell Biochem Funct. 2019 Apr; 37(3):148-152.
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Aten S, Page CE, Kalidindi A, Wheaton K, Niraula A, Godbout JP, Hoyt KR, Obrietan K. miR-132/212 is induced by stress and its dysregulation triggers anxiety-related behavior. Neuropharmacology. 2019 01; 144:256-270.
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Zurlo G, Piquereau J, Moulin M, Pires Da Silva J, Gressette M, Ranchoux B, Garnier A, Ventura-Clapier R, Fadel E, Humbert M, Lemaire C, Perros F, Veksler V. Sirtuin 1 regulates pulmonary artery smooth muscle cell proliferation: role in pulmonary arterial hypertension. J Hypertens. 2018 05; 36(5):1164-1177.
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Cadoni E, Marongiu F, Fanti M, Serra M, Laconi E. Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. Oncotarget. 2017 May 30; 8(22):36020-36032.
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Deota S, Chattopadhyay T, Ramachandran D, Armstrong E, Camacho B, Maniyadath B, Fulzele A, Gonzalez-de-Peredo A, Denu JM, Kolthur-Seetharam U. Identification of a Tissue-Restricted Isoform of SIRT1 Defines a Regulatory Domain that Encodes Specificity. Cell Rep. 2017 03 28; 18(13):3069-3077.
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Paget S, Dubuissez M, Dehennaut V, Nassour J, Harmon BT, Spruyt N, Loison I, Abbadie C, Rood BR, Leprince D. HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs). Oncotarget. 2017 Jan 10; 8(2):2916-2935.
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