Nucleotides adjacent to the ligand-binding pocket are linked to activity tuning in the purine riboswitch.
Stoddard CD, Widmann J, Trausch JJ, Marcano-Vel?zquez JG, Knight R, Batey RT. Nucleotides adjacent to the ligand-binding pocket are linked to activity tuning in the purine riboswitch. J Mol Biol. 2013 May 27; 425(10):1596-611.