A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.

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A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.

Sinkus ML, Lee MJ, Gault J, Logel J, Short M, Freedman R, Christian SL, Lyon J, Leonard S. A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia. Brain Res. 2009 Sep 29; 1291:1-11.

View in: PubMed

subject areas

Alleles
alpha7 Nicotinic Acetylcholine Receptor
Base Sequence
Blotting, Southern
Chromosomes, Human, Pair 15
Female
Gene Dosage
Genetic Predisposition to Disease
Genotype
Humans
In Situ Hybridization, Fluorescence
Male
Patient Selection
Polymorphism, Genetic
Receptors, Nicotinic
Reverse Transcriptase Polymerase Chain Reaction
Schizophrenia
Sequence Deletion

authors with profiles

Robert Freedman
Judith M Gault

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