Kevin Murray
| Title | Research Associate |
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| Institution | University of Colorado Boulder |
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| Department | Integrative Physiology |
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Bibliographic
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Mahoney SA, Mazan-Mamczarz K, Tsitsipatis D, VanDongen NS, Henry-Smith C, Okereke AN, Munk R, Darvish S, Murray KO, De S, Gorospe M, Seals DR, Rossman MJ, Herman AB, Clayton ZS. Senolytic treatment with fisetin reverses age-related endothelial dysfunction partially mediated by SASP factor CXCL12. bioRxiv. 2025 Aug 18. PMID: 40894771.
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Darvish S, Coppock ME, Murray KO, Craighead DH, Chonchol M, Nowak KL, Seals DR, Rossman MJ. Sex-specific effects of mild kidney dysfunction on vascular function in midlife and older adults. Am J Physiol Heart Circ Physiol. 2025 Aug 01; 329(2):H401-H408. PMID: 40623032.
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Murray KO, Laitano O. Is it the heat or the strain? Understanding risk and resilience in heat-exposed laborers. Am J Physiol Regul Integr Comp Physiol. 2025 Jul 01; 329(1):R182-R183. PMID: 40531324.
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Grahnemo L, Marriott RJ, Murray K, Tyack LT, Nethander M, Matsumoto AM, Orwoll ES, Vanderschueren D, Yeap BB, Ohlsson C. Associations of Serum Testosterone and SHBG With Incident Fractures in Middle-aged to Older Men. J Clin Endocrinol Metab. 2025 Jun 17; 110(7):1964-1973. PMID: 39373573.
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Murray KO, Mahoney SA, Ludwig KR, Miyamoto-Ditmon JH, VanDongen NS, Banskota N, Herman AB, Seals DR, Mankowski RT, Rossman MJ, Clayton ZS. Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches. Aging Cell. 2025 Aug; 24(8):e70114. PMID: 40437670.
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Kazmirczak F, Moon R, Vogel NT, Tollison W, Lahti MT, Carney JP, Mendelson JB, Markowski T, Higgins L, Murray K, Guerrero C, Prins KW. Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs. Am J Respir Crit Care Med. 2025 Mar; 211(3):512-515. PMID: 39700526.
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Darvish S, Murray KO, Ludwig KR, Avalani KH, Craighead DH, Freeberg KA, Bevers S, Reisz JA, D'Alessandro A, Moreau KL, Seals DR, Rossman MJ. Preservation of Vascular Endothelial Function in Late-Onset Postmenopausal Women. Circ Res. 2025 Feb 28; 136(5):455-469. PMID: 39886766.
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Narinx N, Marriott RJ, Murray K, Adams RJ, Ballantyne CM, Bauer DC, Bhasin S, Biggs ML, Cawthon PM, Couper DJ, Dobs AS, Flicker L, Hankey GJ, Hannemann A, Wilkening R, Martin SA, Matsumoto AM, Ohlsson C, O'Neill TW, Orwoll ES, Shores MM, Steveling A, Travison TG, Wittert GA, Wu FCW, Antonio L, Vanderschueren D, Yeap BB. Sociodemographic, lifestyle, and medical factors associated with calculated free testosterone concentrations in men: individual participant data meta-analyses. Eur J Endocrinol. 2024 Oct 29; 191(5):523-534. PMID: 39575586.
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Kazmirczak F, Moon R, Vogel NT, Tollison W, T Lahti M, Carney JP, Mendelson JB, Markowski T, Higgins L, Murray K, Guerrero C, Prins KW. Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs. bioRxiv. 2024 Oct 24. PMID: 39484509.
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Clayton ZS, Murray KO. Aerobic Exercise and Obesity-related Insulin Resistance: Using Molecular Patterns to Inform Individualized Prescription. J Clin Endocrinol Metab. 2024 Aug 13; 109(9):e1800-e1801. PMID: 38340335.
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Kruk ME, Mehta S, Murray K, Higgins L, Do K, Johnson JE, Wagner R, Wendt CH, O'Connor JB, Harris JK, Laguna TA, Jagtap PD, Griffin TJ. An integrated metaproteomics workflow for studying host-microbe dynamics in bronchoalveolar lavage samples applied to cystic fibrosis disease. mSystems. 2024 Jul 23; 9(7):e0092923. PMID: 38934598.
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Darvish S, Mahoney SA, Venkatasubramanian R, Rossman MJ, Clayton ZS, Murray KO. Socioeconomic status as a potential mediator of arterial aging in marginalized ethnic and racial groups: current understandings and future directions. J Appl Physiol (1985). 2024 Jul 01; 137(1):194-222. PMID: 38813611.
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Yeap BB, Marriott RJ, Dwivedi G, Adams RJ, Antonio L, Ballantyne CM, Bauer DC, Bhasin S, Biggs ML, Cawthon PM, Couper DJ, Dobs AS, Flicker L, Handelsman DJ, Hankey GJ, Hannemann A, Haring R, Hsu B, Martin SA, Matsumoto AM, Mellström D, Ohlsson C, O'Neill TW, Orwoll ES, Quartagno M, Shores MM, Steveling A, Tivesten Å, Travison TG, Vanderschueren D, Wittert GA, Wu FCW, Murray K. Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men : Individual Participant Data Meta-analyses. Ann Intern Med. 2024 06; 177(6):768-781. PMID: 38739921.
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Avalani KH, Patterson ND, Murray KO. Uterine artery dysfunction in hypoxic pregnancy: a mitochondrial perspective. J Physiol. 2024 May; 602(10):2153-2155. PMID: 38635337.
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Bruzina AS, Raymond-Pope CJ, Murray KJ, Lillquist TJ, Castelli KM, Bijwadia SR, Call JA, Greising SM. Limitations in metabolic plasticity after traumatic injury are only moderately exacerbated by physical activity restriction. NPJ Metab Health Dis. 2024; 2. PMID: 39421399.
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Murray KO, Maurer GS, Gioscia-Ryan RA, Zigler MC, Ludwig KR, D'Alessandro A, Reisz JA, Rossman MJ, Seals DR, Clayton ZS. The plasma metabolome is associated with preservation of physiological function following lifelong aerobic exercise in mice. Geroscience. 2024 06; 46(3):3311-3324. PMID: 38265578.
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Murray KO, Brant JO, Spradlin RA, Thome T, Laitano O, Ryan TE, Riva A, Kladde MP, Clanton TL. Exertional heat stroke causes long-term skeletal muscle epigenetic reprogramming, altered gene expression, and impaired satellite cell function in mice. Am J Physiol Regul Integr Comp Physiol. 2024 02 01; 326(2):R160-R175. PMID: 38047316.
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Gogtay M, Choudhury RS, Williams JP, Mader MJ, Murray KJ, Haro EK, Drum B, O'Brien E, Khosla R, Boyd JS, Bales B, Wetherbee E, Sauthoff H, Schott CK, Basrai Z, Resop D, Lucas BP, Sanchez-Reilly S, Espinosa S, Soni NJ, Nathanson R. Point-of-care ultrasound in geriatrics: a national survey of VA medical centers. BMC Geriatr. 2023 09 27; 23(1):605. PMID: 37759172.
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Marriott RJ, Murray K, Adams RJ, Antonio L, Ballantyne CM, Bauer DC, Bhasin S, Biggs ML, Cawthon PM, Couper DJ, Dobs AS, Flicker L, Handelsman DJ, Hankey GJ, Hannemann A, Haring R, Hsu B, Karlsson M, Martin SA, Matsumoto AM, Mellström D, Ohlsson C, O'Neill TW, Orwoll ES, Quartagno M, Shores MM, Steveling A, Tivesten Å, Travison TG, Vanderschueren D, Wittert GA, Wu FCW, Yeap BB. Factors Associated With Circulating Sex Hormones in Men : Individual Participant Data Meta-analyses. Ann Intern Med. 2023 09; 176(9):1221-1234. PMID: 37639720.
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Peyton MP, Yang TY, Higgins L, Markowski TW, Murray K, Vue C, Parker LL, Lowe DA. Natural aging and ovariectomy induces parallel phosphoproteomic alterations in skeletal muscle of female mice. Aging (Albany NY). 2023 08 14; 15(15):7362-7380. PMID: 37580837.
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Murray KO, Ludwig KR, Darvish S, Coppock ME, Seals DR, Rossman MJ. Chronic mitochondria antioxidant treatment in older adults alters the circulating milieu to improve endothelial cell function and mitochondrial oxidative stress. Am J Physiol Heart Circ Physiol. 2023 07 01; 325(1):H187-H194. PMID: 37326998.
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Schmid R, Heuckeroth S, Korf A, Smirnov A, Myers O, Dyrlund TS, Bushuiev R, Murray KJ, Hoffmann N, Lu M, Sarvepalli A, Zhang Z, Fleischauer M, Dührkop K, Wesner M, Hoogstra SJ, Rudt E, Mokshyna O, Brungs C, Ponomarov K, Mutabd?ija L, Damiani T, Pudney CJ, Earll M, Helmer PO, Fallon TR, Schulze T, Rivas-Ubach A, Bilbao A, Richter H, Nothias LF, Wang M, Ore?ic M, Weng JK, Böcker S, Jeibmann A, Hayen H, Karst U, Dorrestein PC, Petras D, Du X, Pluskal T. Integrative analysis of multimodal mass spectrometry data in MZmine 3. Nat Biotechnol. 2023 04; 41(4):447-449. PMID: 36859716.
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Murray KO, Mahoney SA, Venkatasubramanian R, Seals DR, Clayton ZS. Aging, aerobic exercise, and cardiovascular health: Barriers, alternative strategies and future directions. Exp Gerontol. 2023 03; 173:112105. PMID: 36731386.
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Alzahrani JM, Murray KO, Gambino BJ, Garcia CK, Sheikh LH, Cusack KJ, Laitano O, Clanton TL. Neuromotor deficits and altered physiological responses to repeated exertional heat stroke exposures in mice. Am J Physiol Regul Integr Comp Physiol. 2022 12 01; 323(6):R951-R961. PMID: 36279505.
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Murray KO, Brant JO, Kladde MP, Clanton TL. Long-term epigenetic and metabolomic changes in the mouse ventricular myocardium after exertional heat stroke. Physiol Genomics. 2022 12 01; 54(12):486-500. PMID: 36215393.
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Murray KO, Berryman-Maciel M, Darvish S, Coppock ME, You Z, Chonchol M, Seals DR, Rossman MJ. Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans: A study protocol. Front Physiol. 2022; 13:980783. PMID: 36187760.
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Darvish S, Coppock ME, Murray KO. Age-related impairments in ATP release by red blood cells as an important contributor to declines in skeletal muscle blood flow in older adults. J Physiol. 2022 08; 600(16):3643-3645. PMID: 35818302.
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Murray KO, Clanton TL, Horowitz M. Epigenetic responses to heat: From adaptation to maladaptation. Exp Physiol. 2022 10; 107(10):1144-1158. PMID: 35413138.
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Coppock ME, Freeberg KA, Darvish S, Murray KO. Clinical assessments of cerebrovascular health: is there a neED(D) for cerebral shear-mediated dilatation? J Physiol. 2022 03; 600(6):1287-1289. PMID: 35128665.
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Laitano O, Murray KO, Leon LR. Response to Comment on "Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence vs. Conjecture". Sports Med. 2022 03; 52(3):673-675. PMID: 34626341.
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Laitano O, Pindado J, Valera I, Spradlin RA, Murray KO, Villani KR, Alzahrani JM, Ryan TE, Efron PA, Ferreira LF, Barton ER, Clanton TL. The impact of hindlimb disuse on sepsis-induced myopathy in mice. Physiol Rep. 2021 07; 9(14):e14979. PMID: 34309237.
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Laitano O, Robinson GP, Garcia CK, Mattingly AJ, Sheikh LH, Murray KO, Iwaniec JD, Alzahrani J, Morse D, Hidalgo J, Clanton TL. Skeletal Muscle Interleukin-6 Contributes to the Innate Immune Response in Septic Mice. Shock. 2021 05 01; 55(5):676-685. PMID: 32826815.
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Laitano O, Robinson GP, Murray KO, Garcia CK, Mattingly AJ, Morse D, King MA, Iwaniec JD, Alzahrani JM, Clanton TL. Skeletal muscle fibers play a functional role in host defense during sepsis in mice. Sci Rep. 2021 04 01; 11(1):7316. PMID: 33795743.
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Yeap BB, Marriott RJ, Antonio L, Chan YX, Raj S, Dwivedi G, Reid CM, Anawalt BD, Bhasin S, Dobs AS, Hankey GJ, Matsumoto AM, Norman PE, O'Neill TW, Ohlsson C, Orwoll ES, Vanderschueren D, Wittert GA, Wu FCW, Murray K. Serum Testosterone is Inversely and Sex Hormone-binding Globulin is Directly Associated with All-cause Mortality in Men. J Clin Endocrinol Metab. 2021 01 23; 106(2):e625-e637. PMID: 33059368.
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Murray KO, Brant JO, Iwaniec JD, Sheikh LH, de Carvalho L, Garcia CK, Robinson GP, Alzahrani JM, Riva A, Laitano O, Kladde MP, Clanton TL. Exertional heat stroke leads to concurrent long-term epigenetic memory, immunosuppression and altered heat shock response in female mice. J Physiol. 2021 01; 599(1):119-141. PMID: 33037634.
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Garcia CK, Sheikh LH, Iwaniec JD, Robinson GP, Berlet RA, Mattingly AJ, Murray KO, Laitano O, Clanton TL. Effects of Ibuprofen during Exertional Heat Stroke in Mice. Med Sci Sports Exerc. 2020 09; 52(9):1870-1878. PMID: 32175974.
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Laitano O, Murray KO, Leon LR. Overlapping Mechanisms of Exertional Heat Stroke and Malignant Hyperthermia: Evidence vs. Conjecture. Sports Med. 2020 Sep; 50(9):1581-1592. PMID: 32632746.
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Iwaniec J, Robinson GP, Garcia CK, Murray KO, de Carvalho L, Clanton TL, Laitano O. Acute phase response to exertional heat stroke in mice. Exp Physiol. 2021 01; 106(1):222-232. PMID: 32281170.
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Yeap BB, Marriott RJ, Adams RJ, Antonio L, Ballantyne CM, Bhasin S, Cawthon PM, Couper DJ, Dobs AS, Flicker L, Karlsson M, Martin SA, Matsumoto AM, Mellström D, Norman PE, Ohlsson C, Orwoll ES, O'Neill TW, Shores MM, Travison TG, Vanderschueren D, Wittert GA, Wu FCW, Murray K. Androgens In Men Study (AIMS): protocol for meta-analyses of individual participant data investigating associations of androgens with health outcomes in men. BMJ Open. 2020 05 11; 10(5):e034777. PMID: 32398333.
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Laitano O, Garcia CK, Mattingly AJ, Robinson GP, Murray KO, King MA, Ingram B, Ramamoorthy S, Leon LR, Clanton TL. Delayed metabolic dysfunction in myocardium following exertional heat stroke in mice. J Physiol. 2020 03; 598(5):967-985. PMID: 32026469.
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Laitano O, Sheikh LH, Mattingly AJ, Murray KO, Ferreira LF, Clanton TL. Osmolality Selectively Offsets the Impact of Hyperthermia on Mouse Skeletal Muscle in vitro. Front Physiol. 2018; 9:1496. PMID: 30429796.
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Laitano O, Van Steenbergen D, Mattingly AJ, Garcia CK, Robinson GP, Murray KO, Clanton TL, Nunamaker EA. Xiphoid Surface Temperature Predicts Mortality in a Murine Model of Septic Shock. Shock. 2018 08; 50(2):226-232. PMID: 28957876.
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Crusoe MR, Alameldin HF, Awad S, Boucher E, Caldwell A, Cartwright R, Charbonneau A, Constantinides B, Edvenson G, Fay S, Fenton J, Fenzl T, Fish J, Garcia-Gutierrez L, Garland P, Gluck J, González I, Guermond S, Guo J, Gupta A, Herr JR, Howe A, Hyer A, Härpfer A, Irber L, Kidd R, Lin D, Lippi J, Mansour T, McA'Nulty P, McDonald E, Mizzi J, Murray KD, Nahum JR, Nanlohy K, Nederbragt AJ, Ortiz-Zuazaga H, Ory J, Pell J, Pepe-Ranney C, Russ ZN, Schwarz E, Scott C, Seaman J, Sievert S, Simpson J, Skennerton CT, Spencer J, Srinivasan R, Standage D, Stapleton JA, Steinman SR, Stein J, Taylor B, Trimble W, Wiencko HL, Wright M, Wyss B, Zhang Q, Zyme E, Brown CT. The khmer software package: enabling efficient nucleotide sequence analysis. F1000Res. 2015; 4:900. PMID: 26535114.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2015 | 1 | | 2018 | 2 | | 2020 | 6 | | 2021 | 5 | | 2022 | 6 | | 2023 | 7 | | 2024 | 9 | | 2025 | 7 |
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