Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.

Dmitri Simberg

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOP-Administration
Phone303/724-8241

    Collapse Research 
    Collapse research activities and funding
    R13EB034603     (SIMBERG, DMITRI)Mar 1, 2023 - Feb 29, 2024
    NIH
    Mechanisms and Barriers in Nanomedicine-2023
    Role: Principal Investigator
    R01CA257958     (SIMBERG, DMITRI)Aug 1, 2022 - Jul 31, 2027
    NIH
    Fluorescent Indocarbocyanine PEGylated Lipid Nanoparticles for Understanding and Overcoming Barriers to Drug Delivery in Invasive Glioblastoma
    Role: Principal Investigator
    R13EB021826     (SIMBERG, DIMITRI)Jul 1, 2016 - Jun 30, 2017
    NIH
    Mechanisms and barriers in nanomedicine
    Role: Principal Investigator
    R01AI154959     (SIMBERG, DMITRI)Jun 1, 2016 - Jun 30, 2025
    NIH
    The Alternative Complement Pathway and Hemocompatibility of Nanosurfaces
    Role: Principal Investigator
    R01EB022040     (SIMBERG, DIMITRI)Jun 1, 2016 - Jun 10, 2020
    NIH
    The alternative complement pathway and hemocompatibility of nanosurfaces
    Role: Principal Investigator
    R01CA194058     (SIMBERG, DIMITRI)Dec 15, 2015 - Nov 30, 2021
    NIH
    Painted erythrocyte carriers for therapy of acute myeloid leukemia
    Role: Principal Investigator
    R21CA167524     (SIMBERG, DIMITRI)Apr 1, 2012 - Mar 31, 2016
    NIH
    Photo-assisted targeting of immunotherapy to the bladder
    Role: Principal Investigator
    R21CA164880     (LIU, YU-TSUENG)Mar 1, 2012 - Feb 28, 2014
    NIH
    Non-invasive sampling of DNA markers for pancreatic cancer screening
    Role: Co-Principal Investigator
    R21CA137721     (SIMBERG, DIMITRI)Jun 1, 2009 - May 31, 2012
    NIH
    Isolation of rare circulating tumor cells from blood using microbubbles
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Li Y, Moein Moghimi S, Simberg D. Complement-dependent uptake of nanoparticles by blood phagocytes: brief overview and perspective. Curr Opin Biotechnol. 2024 02; 85:103044. PMID: 38091875.
      View in: PubMed
    2. Haroon HB, Dhillon E, Farhangrazi ZS, Trohopoulos PN, Simberg D, Moghimi SM. Activation of the complement system by nanoparticles and strategies for complement inhibition. Eur J Pharm Biopharm. 2023 Dec; 193:227-240. PMID: 37949325.
      View in: PubMed
    3. Li Y, Jacques S, Gaikwad H, Wang G, Banda NK, Holers VM, Scheinman RI, Tomlinson S, Moghimi SM, Simberg D. Inhibition of acute complement responses towards bolus-injected nanoparticles using targeted short-circulating regulatory proteins. Nat Nanotechnol. 2024 Feb; 19(2):246-254. PMID: 37798566.
      View in: PubMed
    4. Moghimi SM, Haroon HB, Yaghmur A, Hunter AC, Papini E, Farhangrazi ZS, Simberg D, Trohopoulos PN. Perspectives on complement and phagocytic cell responses to nanoparticles: From fundamentals to adverse reactions. J Control Release. 2023 04; 356:115-129. PMID: 36841287.
      View in: PubMed
    5. Moghimi SM, McCullough R, Simberg D. Revisiting nanoparticle transendothelial migration in the liver. Mol Ther. 2023 03 01; 31(3):605-606. PMID: 36754053.
      View in: PubMed
    6. Moghimi SM, Haroon HB, Yaghmur A, Simberg D, Trohopoulos PN. Nanometer- and angstrom-scale characteristics that modulate complement responses to nanoparticles. J Control Release. 2022 11; 351:432-443. PMID: 36152807.
      View in: PubMed
    7. Gaikwad H, Wang G, Li Y, Bourne D, Simberg D. Surface Modification of Erythrocytes with Lipid Anchors: Structure-Activity Relationship for Optimal Membrane Incorporation, in vivo Retention, and Immunocompatibility. Adv Nanobiomed Res. 2022 Aug; 2(8). PMID: 36591390.
      View in: PubMed
    8. Balyasnikova IV, Zannikou M, Wang G, Li Y, Duffy JT, Levine RN, Seblani M, Gaikwad H, Simberg D. Indocarbocyanine nanoparticles extravasate and distribute better than liposomes in brain tumors. J Control Release. 2022 09; 349:413-424. PMID: 35817279.
      View in: PubMed
    9. Gaikwad H, Li Y, Wang G, Li R, Dai S, Rester C, Kedl R, Saba L, Banda NK, Scheinman RI, Patrick C, Mallela KMG, Moghimi SM, Simberg D. Antibody-Dependent Complement Responses toward SARS-CoV-2 Receptor-Binding Domain Immobilized on "Pseudovirus-like" Nanoparticles. ACS Nano. 2022 May 04. PMID: 35507641.
      View in: PubMed
    10. Moghimi SM, Simberg D. Pro-inflammatory concerns with lipid nanoparticles. Mol Ther. 2022 06 01; 30(6):2109-2110. PMID: 35487214.
      View in: PubMed
    11. Li Y, Lofchy L, Wang G, Gaikwad H, Fujita M, Simberg D. PEGylated Liposomes Accumulate in the Areas Relevant to Skin Toxicities via Passive Extravasation across "Leaky" Endothelium. ACS Nano. 2022 Apr 26; 16(4):6349-6358. PMID: 35343675.
      View in: PubMed
    12. Gaikwad H, Li Y, Gifford G, Groman E, Banda NK, Saba L, Scheinman R, Wang G, Simberg D. Correction to "Complement Inhibitors Block Complement C3 Opsonization and Improve Targeting Selectivity of Nanoparticles in Blood". Bioconjug Chem. 2021 Sep 15; 32(9):2128. PMID: 34478264.
      View in: PubMed
    13. Li Y, Wang G, Griffin L, Banda NK, Saba LM, Groman EV, Scheinman R, Moghimi SM, Simberg D. Complement opsonization of nanoparticles: Differences between humans and preclinical species. J Control Release. 2021 10 10; 338:548-556. PMID: 34481928.
      View in: PubMed
    14. Zhang W, Gaikwad H, Groman EV, Purev E, Simberg D, Wang G. Highly aminated iron oxide nanoworms for simultaneous manufacturing and labeling of chimeric antigen receptor T cells. J Magn Magn Mater. 2022 Jan 01; 541. PMID: 34720339.
      View in: PubMed
    15. Wu LP, Ficker M, Christensen JB, Simberg D, Trohopoulos PN, Moghimi SM. Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking. Nat Commun. 2021 08 11; 12(1):4858. PMID: 34381048.
      View in: PubMed
    16. Wang G, Zannikou M, Lofchy L, Li Y, Gaikwad H, Balyasnikova IV, Simberg D. Liposomal Extravasation and Accumulation in Tumors as Studied by Fluorescence Microscopy and Imaging Depend on the Fluorescent Label. ACS Nano. 2021 Jul 27; 15(7):11880-11890. PMID: 34197075.
      View in: PubMed
    17. Catala A, Dzieciatkowska M, Wang G, Gutierrez-Hartmann A, Simberg D, Hansen KC, D'Alessandro A, Catalano CE. Targeted Intracellular Delivery of Trastuzumab Using Designer Phage Lambda Nanoparticles Alters Cellular Programs in Human Breast Cancer Cells. ACS Nano. 2021 Jul 27; 15(7):11789-11805. PMID: 34189924.
      View in: PubMed
    18. Wang G, Gaikwad H, McCarthy MK, Gonzalez-Juarrero M, Li Y, Armstrong M, Reisdorph N, Morrison TE, Simberg D. Lipid nanoparticle formulation of niclosamide (nano NCM) effectively inhibits SARS-CoV-2 replication in vitro. Precis Nanomed. 2021 Apr 17; 4(1):724-737. PMID: 34676370.
      View in: PubMed
    19. Serkova NJ, Glunde K, Haney CR, Farhoud M, De Lille A, Redente EF, Simberg D, Westerly DC, Griffin L, Mason RP. Preclinical Applications of Multi-Platform Imaging in Animal Models of Cancer. Cancer Res. 2021 03 01; 81(5):1189-1200. PMID: 33262127.
      View in: PubMed
    20. Banda NK, Tomlinson S, Scheinman RI, Ho N, Ramirez JR, Mehta G, Wang G, Vu VP, Simberg D, Kulik L, Holers VM. C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice. Front Immunol. 2020; 11:575154. PMID: 33178202.
      View in: PubMed
    21. Ren P, Yang C, Lofchy LA, Wang G, Chen F, Simberg D. Establishing In Situ Closed Circuit Perfusion of Lower Abdominal Organs and Hind Limbs in Mice. J Vis Exp. 2020 08 13; (162). PMID: 32865531.
      View in: PubMed
    22. Yang C, Chen F, Ren P, Lofchy L, Wan C, Shen J, Wang G, Gaikwad H, Ponder J, Jordan CT, Scheinman R, Simberg D. Delivery of a model lipophilic membrane cargo to bone marrow via cell-derived microparticles. J Control Release. 2020 10 10; 326:324-334. PMID: 32682903.
      View in: PubMed
    23. Gaikwad H, Li Y, Gifford G, Groman E, Banda NK, Saba L, Scheinman R, Wang G, Simberg D. Complement Inhibitors Block Complement C3 Opsonization and Improve Targeting Selectivity of Nanoparticles in Blood. Bioconjug Chem. 2020 07 15; 31(7):1844-1856. PMID: 32598839.
      View in: PubMed
    24. Moghimi SM, Simberg D, Papini E, Farhangrazi ZS. Complement activation by drug carriers and particulate pharmaceuticals: Principles, challenges and opportunities. Adv Drug Deliv Rev. 2020; 157:83-95. PMID: 32389761.
      View in: PubMed
    25. Moghimi SM, Simberg D, Anchordoquy TJ. Tuning the Engines of Nanomedicine. Mol Ther. 2020 03 04; 28(3):693-694. PMID: 32032534.
      View in: PubMed
    26. Wang G, Serkova NJ, Groman EV, Scheinman RI, Simberg D. Feraheme (Ferumoxytol) Is Recognized by Proinflammatory and Anti-inflammatory Macrophages via Scavenger Receptor Type AI/II. Mol Pharm. 2019 10 07; 16(10):4274-4281. PMID: 31556296.
      View in: PubMed
    27. Lofchy LA, Vu VP, Banda NK, Ramirez JR, Smith WJ, Gifford G, Gaikwad H, Scheinman RI, Simberg D. Evaluation of Targeting Efficiency of Joints with Anticollagen II Antibodies. Mol Pharm. 2019 06 03; 16(6):2445-2451. PMID: 31091104.
      View in: PubMed
    28. Gaikwad H, Wang G, Smith WJ, Alexander KL, D'Alessandro A, Zhang W, Purev E, Simberg D. Clickable Methyltetrazine-Indocarbocyanine Lipids: A Multicolor Tool Kit for Efficient Modifications of Cell Membranes. Bioconjug Chem. 2019 08 21; 30(8):2106-2114. PMID: 31050882.
      View in: PubMed
    29. Gifford G, Vu VP, Banda NK, Holers VM, Wang G, Groman EV, Backos D, Scheinman R, Moghimi SM, Simberg D. Complement therapeutics meets nanomedicine: overcoming human complement activation and leukocyte uptake of nanomedicines with soluble domains of CD55. J Control Release. 2019 05 28; 302:181-189. PMID: 30974134.
      View in: PubMed
    30. Moghimi SM, Simberg D, Skotland T, Yaghmur A, Hunter AC. The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses. J Pharmacol Exp Ther. 2019 09; 370(3):581-592. PMID: 30940695.
      View in: PubMed
    31. Vu VP, Gifford GB, Chen F, Benasutti H, Wang G, Groman EV, Scheinman R, Saba L, Moghimi SM, Simberg D. Publisher Correction: Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles. Nat Nanotechnol. 2019 Mar; 14(3):298. PMID: 30670872.
      View in: PubMed
    32. Benchimol MJ, Bourne D, Moghimi SM, Simberg D. Pharmacokinetic analysis reveals limitations and opportunities for nanomedicine targeting of endothelial and extravascular compartments of tumours. J Drug Target. 2019 Jun - Jul; 27(5-6):690-698. PMID: 30614276.
      View in: PubMed
    33. Vu VP, Gifford GB, Chen F, Benasutti H, Wang G, Groman EV, Scheinman R, Saba L, Moghimi SM, Simberg D. Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles. Nat Nanotechnol. 2019 03; 14(3):260-268. PMID: 30643271.
      View in: PubMed
    34. Smith WJ, Wang G, Gaikwad H, Vu VP, Groman E, Bourne DWA, Simberg D. Accelerated Blood Clearance of Antibodies by Nanosized Click Antidotes. ACS Nano. 2018 12 26; 12(12):12523-12532. PMID: 30516974.
      View in: PubMed
    35. Szebeni J, Simberg D, Gonz?lez-Fern?ndez ?, Barenholz Y, Dobrovolskaia MA. Roadmap and strategy for overcoming infusion reactions to nanomedicines. Nat Nanotechnol. 2018 12; 13(12):1100-1108. PMID: 30348955.
      View in: PubMed
    36. Moghimi SM, Simberg D. Nanoparticle transport pathways into tumors. J Nanopart Res. 2018; 20(6):169. PMID: 29950922.
      View in: PubMed
    37. Tavano R, Gabrielli L, Lubian E, Fedeli C, Visentin S, Polverino De Laureto P, Arrigoni G, Geffner-Smith A, Chen F, Simberg D, Morgese G, Benetti EM, Wu L, Moghimi SM, Mancin F, Papini E. C1q-Mediated Complement Activation and C3 Opsonization Trigger Recognition of Stealth Poly(2-methyl-2-oxazoline)-Coated Silica Nanoparticles by Human Phagocytes. ACS Nano. 2018 06 26; 12(6):5834-5847. PMID: 29750504.
      View in: PubMed
    38. Moghimi SM, Simberg D. Translational gaps in animal models of human infusion reactions to nanomedicines. Nanomedicine (Lond). 2018 05; 13(9):973-975. PMID: 29790401.
      View in: PubMed
    39. Smith WJ, Tran H, Griffin JI, Jones J, Vu VP, Nilewski L, Gianneschi N, Simberg D. Lipophilic indocarbocyanine conjugates for efficient incorporation of enzymes, antibodies and small molecules into biological membranes. Biomaterials. 2018 04; 161:57-68. PMID: 29421563.
      View in: PubMed
    40. Benasutti H, Wang G, Vu VP, Scheinman R, Groman E, Saba L, Simberg D. Variability of Complement Response toward Preclinical and Clinical Nanocarriers in the General Population. Bioconjug Chem. 2017 11 15; 28(11):2747-2755. PMID: 29090582.
      View in: PubMed
    41. Wang G, Benasutti H, Jones JF, Shi G, Benchimol M, Pingle S, Kesari S, Yeh Y, Hsieh LE, Liu YT, Elias A, Simberg D. Isolation of Breast cancer CTCs with multitargeted buoyant immunomicrobubbles. Colloids Surf B Biointerfaces. 2018 Jan 01; 161:200-209. PMID: 29080504.
      View in: PubMed
    42. Griffin JI, Wang G, Smith WJ, Vu VP, Scheinman R, Stitch D, Moldovan R, Moghimi SM, Simberg D. Revealing Dynamics of Accumulation of Systemically Injected Liposomes in the Skin by Intravital Microscopy. ACS Nano. 2017 11 28; 11(11):11584-11593. PMID: 29045127.
      View in: PubMed
    43. Wu L, Uldahl KB, Chen F, Benasutti H, Logvinski D, Vu V, Banda NK, Peng X, Simberg D, Moghimi SM. Interaction of extremophilic archaeal viruses with human and mouse complement system and viral biodistribution in mice. Mol Immunol. 2017 10; 90:273-279. PMID: 28846925.
      View in: PubMed
    44. Anchordoquy TJ, Simberg D. Watching the gorilla and questioning delivery dogma. J Control Release. 2017 09 28; 262:87-90. PMID: 28713040.
      View in: PubMed
    45. Griffin JI, Cheng SKK, Hayashi T, Carson D, Saraswathy M, Nair DP, Simberg D. Cell-penetrating peptide CGKRK mediates efficient and widespread targeting of bladder mucosa following focal injury. Nanomedicine. 2017 Aug; 13(6):1925-1932. PMID: 28428051.
      View in: PubMed
    46. Moghimi SM, Simberg D. Complement activation turnover on surfaces of nanoparticles. Nano Today. 2017 Aug; 15:8-10. PMID: 29399037.
      View in: PubMed
    47. Wang G, Griffin JI, Inturi S, Brenneman B, Banda NK, Holers VM, Moghimi SM, Simberg D. In Vitro and In Vivo Differences in Murine Third Complement Component (C3) Opsonization and Macrophage/Leukocyte Responses to Antibody-Functionalized Iron Oxide Nanoworms. Front Immunol. 2017; 8:151. PMID: 28239384.
      View in: PubMed
    48. Anchordoquy TJ, Barenholz Y, Boraschi D, Chorny M, Decuzzi P, Dobrovolskaia MA, Farhangrazi ZS, Farrell D, Gabizon A, Ghandehari H, Godin B, La-Beck NM, Ljubimova J, Moghimi SM, Pagliaro L, Park JH, Peer D, Ruoslahti E, Serkova NJ, Simberg D. Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions. ACS Nano. 2017 01 24; 11(1):12-18. PMID: 28068099.
      View in: PubMed
    49. Griffin JI, Benchimol MJ, Simberg D. Longitudinal monitoring of skin accumulation of nanocarriers and biologicals with fiber optic near infrared fluorescence spectroscopy (FONIRS). J Control Release. 2017 02 10; 247:167-174. PMID: 28069552.
      View in: PubMed
    50. Chen F, Wang G, Griffin JI, Brenneman B, Banda NK, Holers VM, Backos DS, Wu L, Moghimi SM, Simberg D. Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo. Nat Nanotechnol. 2017 05; 12(4):387-393. PMID: 27992410.
      View in: PubMed
    51. Wang G, Chen F, Banda NK, Holers VM, Wu L, Moghimi SM, Simberg D. Activation of Human Complement System by Dextran-Coated Iron Oxide Nanoparticles Is Not Affected by Dextran/Fe Ratio, Hydroxyl Modifications, and Crosslinking. Front Immunol. 2016; 7:418. PMID: 27777575.
      View in: PubMed
    52. Simberg D. Iron oxide nanoparticles and the mechanisms of immune recognition of nanomedicines. Nanomedicine (Lond). 2016 Apr; 11(7):741-3. PMID: 26979409.
      View in: PubMed
    53. Inturi S, Wang G, Chen F, Banda NK, Holers VM, Wu L, Moghimi SM, Simberg D. Modulatory Role of Surface Coating of Superparamagnetic Iron Oxide Nanoworms in Complement Opsonization and Leukocyte Uptake. ACS Nano. 2015 Nov 24; 9(11):10758-68. PMID: 26488074.
      View in: PubMed
    54. Simberg D. Opening Windows into Tumors. ACS Nano. 2015 Sep 22; 9(9):8647-50. PMID: 26340308.
      View in: PubMed
    55. Wang G, Inturi S, Serkova NJ, Merkulov S, McCrae K, Russek SE, Banda NK, Simberg D. High-relaxivity superparamagnetic iron oxide nanoworms with decreased immune recognition and long-circulating properties. ACS Nano. 2014 Dec 23; 8(12):12437-49. PMID: 25419856.
      View in: PubMed
    56. Banda NK, Mehta G, Chao Y, Wang G, Inturi S, Fossati-Jimack L, Botto M, Wu L, Moghimi SM, Simberg D. Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum. Part Fibre Toxicol. 2014 Nov 26; 11:64. PMID: 25425420.
      View in: PubMed
    57. Ibsen S, Shi G, Schutt C, Shi L, Suico KD, Benchimol M, Serra V, Simberg D, Berns M, Esener S. The behavior of lipid debris left on cell surfaces from microbubble based ultrasound molecular imaging. Ultrasonics. 2014 Dec; 54(8):2090-8. PMID: 25059435.
      View in: PubMed
    58. Mukthavaram R, Shi G, Kesari S, Simberg D. Targeting and depletion of circulating leukocytes and cancer cells by lipophilic antibody-modified erythrocytes. J Control Release. 2014 Jun 10; 183:146-53. PMID: 24685706.
      View in: PubMed
    59. Ortac I, Simberg D, Yeh YS, Yang J, Messmer B, Trogler WC, Tsien RY, Esener S. Dual-porosity hollow nanoparticles for the immunoprotection and delivery of nonhuman enzymes. Nano Lett. 2014 Jun 11; 14(6):3023-32. PMID: 24471767.
      View in: PubMed
    60. Mukthavaram R, Jiang P, Saklecha R, Simberg D, Bharati IS, Nomura N, Chao Y, Pastorino S, Pingle SC, Fogal V, Wrasidlo W, Makale M, Kesari S. High-efficiency liposomal encapsulation of a tyrosine kinase inhibitor leads to improved in vivo toxicity and tumor response profile. Int J Nanomedicine. 2013; 8:3991-4006. PMID: 24174874.
      View in: PubMed
    61. Shi G, Cui W, Mukthavaram R, Liu YT, Simberg D. Binding and isolation of tumor cells in biological media with perfluorocarbon microbubbles. Methods. 2013 Dec 01; 64(2):102-7. PMID: 23974072.
      View in: PubMed
    62. Shi G, Mukthavaram R, Kesari S, Simberg D. Distearoyl anchor-painted erythrocytes with prolonged ligand retention and circulation properties in vivo. Adv Healthc Mater. 2014 Jan; 3(1):142-8. PMID: 23798381.
      View in: PubMed
    63. Chao Y, Karmali PP, Mukthavaram R, Kesari S, Kouznetsova VL, Tsigelny IF, Simberg D. Direct recognition of superparamagnetic nanocrystals by macrophage scavenger receptor SR-AI. ACS Nano. 2013 May 28; 7(5):4289-98. PMID: 23614696.
      View in: PubMed
    64. Shi G, Cui W, Benchimol M, Liu YT, Mattrey RF, Mukthavaram R, Kesari S, Esener SC, Simberg D. Isolation of rare tumor cells from blood cells with buoyant immuno-microbubbles. PLoS One. 2013; 8(3):e58017. PMID: 23516425.
      View in: PubMed
    65. Chao Y, Makale M, Karmali PP, Sharikov Y, Tsigelny I, Merkulov S, Kesari S, Wrasidlo W, Ruoslahti E, Simberg D. Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains. Bioconjug Chem. 2012 May 16; 23(5):1003-9. PMID: 22515422.
      View in: PubMed
    66. Karmali PP, Chao Y, Park JH, Sailor MJ, Ruoslahti E, Esener SC, Simberg D. Different effect of hydrogelation on antifouling and circulation properties of dextran-iron oxide nanoparticles. Mol Pharm. 2012 Mar 05; 9(3):539-45. PMID: 22243419.
      View in: PubMed
    67. Ibsen S, Benchimol M, Simberg D, Esener S. Ultrasound mediated localized drug delivery. Adv Exp Med Biol. 2012; 733:145-53. PMID: 22101720.
      View in: PubMed
    68. Chao Y, Karmali PP, Simberg D. Role of carbohydrate receptors in the macrophage uptake of dextran-coated iron oxide nanoparticles. Adv Exp Med Biol. 2012; 733:115-23. PMID: 22101717.
      View in: PubMed
    69. Ibsen S, Benchimol M, Simberg D, Schutt C, Steiner J, Esener S. A novel nested liposome drug delivery vehicle capable of ultrasound triggered release of its payload. J Control Release. 2011 Nov 07; 155(3):358-66. PMID: 21745505.
      View in: PubMed
    70. Karmali PP, Simberg D. Interactions of nanoparticles with plasma proteins: implication on clearance and toxicity of drug delivery systems. Expert Opin Drug Deliv. 2011 Mar; 8(3):343-57. PMID: 21291354.
      View in: PubMed
    71. Simberg D, Zhang WM, Merkulov S, McCrae K, Park JH, Sailor MJ, Ruoslahti E. Contact activation of kallikrein-kinin system by superparamagnetic iron oxide nanoparticles in vitro and in vivo. J Control Release. 2009 Dec 16; 140(3):301-5. PMID: 19508879.
      View in: PubMed
    72. Simberg D, Mattrey R. Targeting of perfluorocarbon microbubbles to selective populations of circulating blood cells. J Drug Target. 2009 Jun; 17(5):392-8. PMID: 19505207.
      View in: PubMed
    73. Simberg D, Park JH, Karmali PP, Zhang WM, Merkulov S, McCrae K, Bhatia SN, Sailor M, Ruoslahti E. Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance. Biomaterials. 2009 Aug; 30(23-24):3926-33. PMID: 19394687.
      View in: PubMed
    74. Park JH, von Maltzahn G, Zhang L, Derfus AM, Simberg D, Harris TJ, Ruoslahti E, Bhatia SN, Sailor MJ. Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting. Small. 2009 Mar; 5(6):694-700. PMID: 19263431.
      View in: PubMed
    75. Simberg D, Duza T, Park JH, Essler M, Pilch J, Zhang L, Derfus AM, Yang M, Hoffman RM, Bhatia S, Sailor MJ, Ruoslahti E. Biomimetic amplification of nanoparticle homing to tumors. Proc Natl Acad Sci U S A. 2007 Jan 16; 104(3):932-6. PMID: 17215365.
      View in: PubMed
    76. Khazanov E, Simberg D, Barenholz Y. Lipoplexes prepared from cationic liposomes and mammalian DNA induce CpG-independent, direct cytotoxic effects in cell cultures and in mice. J Gene Med. 2006 Aug; 8(8):998-1007. PMID: 16741997.
      View in: PubMed
    77. Joseph A, Itskovitz-Cooper N, Samira S, Flasterstein O, Eliyahu H, Simberg D, Goldwaser I, Barenholz Y, Kedar E. A new intranasal influenza vaccine based on a novel polycationic lipid--ceramide carbamoyl-spermine (CCS) I. Immunogenicity and efficacy studies in mice. Vaccine. 2006 May 01; 24(18):3990-4006. PMID: 16516356.
      View in: PubMed
    78. Simberg D, Weiss A, Barenholz Y. Reversible mode of binding of serum proteins to DOTAP/cholesterol Lipoplexes: a possible explanation for intravenous lipofection efficiency. Hum Gene Ther. 2005 Sep; 16(9):1087-96. PMID: 16149907.
      View in: PubMed
    79. Simberg D, Weisman S, Talmon Y, Barenholz Y. DOTAP (and other cationic lipids): chemistry, biophysics, and transfection. Crit Rev Ther Drug Carrier Syst. 2004; 21(4):257-317. PMID: 15638468.
      View in: PubMed
    80. Simberg D, Weisman S, Talmon Y, Faerman A, Shoshani T, Barenholz Y. The role of organ vascularization and lipoplex-serum initial contact in intravenous murine lipofection. J Biol Chem. 2003 Oct 10; 278(41):39858-65. PMID: 12869564.
      View in: PubMed
    81. Simberg D, Danino D, Talmon Y, Minsky A, Ferrari ME, Wheeler CJ, Barenholz Y. Phase behavior, DNA ordering, and size instability of cationic lipoplexes. Relevance to optimal transfection activity. J Biol Chem. 2001 Dec 14; 276(50):47453-9. PMID: 11564736.
      View in: PubMed
    Simberg's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (322) concept(s)
    _
    Co-Authors Expand Description
    See all (22) people
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department

    Copyright © 2024 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)