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John E Repine

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Webb Waring Center
Phone303/724-4788

    Collapse Research 
    Collapse research activities and funding
    R01HL028182     (REPINE, JOHN E)Jan 1, 1982 - Dec 31, 1987
    NIH/NHLBI
    NEUTROPHIL AND O2 RADICAL MEDIATED ENDOTHELIAL INJURY
    Role: Principal Investigator
    T35DK007496     (REPINE, JOHN E)May 1, 1985 - Apr 30, 2006
    NIH/NIDDK
    Short-Term Training In Health Professional School
    Role: Principal Investigator
    R01HL034486     (REPINE, JOHN E)Jul 1, 1985 - Jun 30, 1988
    NIH/NHLBI
    MEASUREMENT OF O2 RADICALS IN BIOLOGICAL SYSTEMS
    Role: Principal Investigator
    R01HL035378     (REPINE, JOHN E)Apr 1, 1987 - Mar 31, 1990
    NIH/NHLBI
    ERYTHROCYTE ANTIOXIDANTS AND RESPIRATORY PHYSIOLOGY
    Role: Principal Investigator
    P50HL040784     (REPINE, JOHN E)Dec 1, 1988 - Jun 30, 1999
    NIH/NHLBI
    SCOR IN ACUTE LUNG INJURY
    Role: Principal Investigator
    R01HL045582     (REPINE, JOHN E)Feb 10, 1992 - Dec 31, 2011
    NIH/NHLBI
    Respiratory Endothelial Injury by Xanthine Oxidase
    Role: Principal Investigator
    R25HL108823     (REPINE, JOHN E)May 1, 2011 - Apr 30, 2022
    NIH/NHLBI
    Colorado Summer Research Training for Undergraduate Diversity
    Role: Principal Investigator
    R25ES025476     (BROWN, JARED MICHAEL)Apr 2, 2015 - Mar 31, 2020
    NIH/NIEHS
    Colorado Undergraduate Research in Environmental Health Sciences
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Afshar M, Burnham EL, Joyce C, Gagnon R, Dunn R, Albright JM, Ramirez L, Repine JE, Netzer G, Kovacs EJ. Injury Characteristics and von Willebrand Factor for the Prediction of Acute Respiratory Distress Syndrome in Patients With Burn Injury: Development and Internal Validation. Ann Surg. 2018 Apr 24. PMID: 29697443.
      View in: PubMed
    2. Alhalwani AY, Repine JE, Knowles MK, Huffman JA. Development of a sandwich ELISA with potential for selective quantification of human lactoferrin protein nitrated through disease or environmental exposure. Anal Bioanal Chem. 2018 Feb; 410(4):1389-1396. PMID: 29214534.
      View in: PubMed
    3. Repine JE, Wilson P, Elkins N, Klawitter J, Christians U, Peters B, Smith DM. Inhalation of two putative Gulf War toxins by mice. J Environ Sci Health B. 2016; 51(6):366-73. PMID: 26950528.
      View in: PubMed
    4. Christopher KL, Repine JE. Rebuttal From Drs Christopher and Repine. Chest. 2016 Feb; 149(2):309-310. PMID: 26867831.
      View in: PubMed
    5. Christopher KL, Repine JE. COUNTERPOINT: Does Low-Dose Oxygen Expose Patients With COPD to More Radiation-Like Risks Than Patients Without COPD? No. Chest. 2016 Feb; 149(2):306-308. PMID: 26867829.
      View in: PubMed
    6. Fernandez-Bustamante A, Agazio A, Wilson P, Elkins N, Domaleski L, He Q, Baer KA, Moss AF, Wischmeyer PE, Repine JE. Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in IL-1/LPS-Insufflated Rats. PLoS One. 2015; 10(7):e0130764. PMID: 26147379; PMCID: PMC4493112.
      View in: PubMed, PubMed Central
    7. Fernandez-Bustamante A, Hashimoto S, Serpa Neto A, Moine P, Vidal Melo MF, Repine JE. Perioperative lung protective ventilation in obese patients. BMC Anesthesiol. 2015 May 06; 15:56. PMID: 25907273; PMCID: PMC4491899.
      View in: PubMed, PubMed Central
    8. Fernandez-Bustamante A, Klawitter J, Repine JE, Agazio A, Janocha AJ, Shah C, Moss M, Douglas IS, Tran ZV, Erzurum SC, Christians U, Seres T. Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs. Anesthesiology. 2014 Sep; 121(3):469-81. PMID: 24809976; PMCID: PMC4165799.
      View in: PubMed, PubMed Central
    9. Fernandez-Bustamante A, Repine JE. Chronic inflammatory diseases and the Acute Respiratory Distress Syndrome (ARDS). Curr Pharm Des. 2014; 20(9):1400-8. PMID: 23978096.
      View in: PubMed
    10. Fernandez-Bustamante A, Klawitter J, Wilson P, Elkins ND, Agazio A, Shibata T, Uchida K, Christians U, Repine JE. Early increase in alveolar macrophage prostaglandin 15d-PGJ2 precedes neutrophil recruitment into lungs of cytokine-insufflated rats. Inflammation. 2013 Oct; 36(5):1030-40. PMID: 23616184.
      View in: PubMed
    11. Aruoma OI, Coles LS, Landes B, Repine JE. Functional benefits of ergothioneine and fruit- and vegetable-derived nutraceuticals: overview of the supplemental issue contents. Prev Med. 2012 May; 54 Suppl:S4-8. PMID: 22579240.
      View in: PubMed
    12. Repine JE, Elkins ND. Effect of ergothioneine on acute lung injury and inflammation in cytokine insufflated rats. Prev Med. 2012 May; 54 Suppl:S79-82. PMID: 22197759; PMCID: PMC3355229.
      View in: PubMed, PubMed Central
    13. Repine JJ, Crader KM, Elkins ND, Wilson P, Repine JE. Preventing the acute respiratory distress syndrome. Prev Med. 2012 May; 54 Suppl:S17-9. PMID: 22197762.
      View in: PubMed
    14. Stupic KF, Elkins ND, Pavlovskaya GE, Repine JE, Meersmann T. Effects of pulmonary inhalation on hyperpolarized krypton-83 magnetic resonance T1 relaxation. Phys Med Biol. 2011 Jul 07; 56(13):3731-48. PMID: 21628780; PMCID: PMC3249834.
      View in: PubMed, PubMed Central
    15. Repine JE, Reiss OK, Elkins N, Chughtai AR, Smith DM. Effects of fine carbonaceous particles containing high and low unpaired electron spin densities on lungs of female mice. Transl Res. 2008 Oct; 152(4):185-93. PMID: 18940721.
      View in: PubMed
    16. Cleveland ZI, Pavlovskaya GE, Elkins ND, Stupic KF, Repine JE, Meersmann T. Hyperpolarized 83Kr MRI of lungs. J Magn Reson. 2008 Dec; 195(2):232-7. PMID: 18948043.
      View in: PubMed
    17. Parmley LA, Elkins ND, Fini MA, Liu YE, Repine JE, Wright RM. Alpha-4/beta-1 and alpha-L/beta-2 integrins mediate cytokine induced lung leukocyte-epithelial adhesion and injury. Br J Pharmacol. 2007 Nov; 152(6):915-29. PMID: 17828290; PMCID: PMC2078224.
      View in: PubMed, PubMed Central
    18. Cleveland ZI, Pavlovskaya GE, Stupic KF, Wooten JB, Repine JE, Meersmann T. Detection of tobacco smoke deposition by hyperpolarized krypton-83 MRI. Magn Reson Imaging. 2008 Feb; 26(2):270-8. PMID: 17826938.
      View in: PubMed
    19. Cleveland ZI, Stupic KF, Pavlovskaya GE, Repine JE, Wooten JB, Meersmann T. Hyperpolarized 83Kr and 129Xe NMR relaxation measurements of hydrated surfaces: implications for materials science and pulmonary diagnostics. J Am Chem Soc. 2007 Feb 14; 129(6):1784-92. PMID: 17243679.
      View in: PubMed
    20. Dunn JS, Nayar R, Campos J, Hybertson BM, Zhou Y, Manning MC, Repine JE, Stringer KA. Feasibility of tissue plasminogen activator formulated for pulmonary delivery. Pharm Res. 2005 Oct; 22(10):1700-7. PMID: 16180128; PMCID: PMC2040297.
      View in: PubMed, PubMed Central
    21. Hybertson BM, Chung JH, Fini MA, Lee YM, Allard JD, Hansen BN, Cho OJ, Shibao GN, Repine JE. Aerosol-administered alpha-tocopherol attenuates lung inflammation in rats given lipopolysaccharide intratracheally. Exp Lung Res. 2005 Apr; 31(3):283-94. PMID: 15962709.
      View in: PubMed
    22. Yoon-yub P, Hybertson B, Wright R, Fini M, Elkins N, Repine J. Serum ferritin elevation and acute lung injury in rats subjected to hemorrhage: reduction by mepacrine treatment. Exp Lung Res. 2004 Oct-Nov; 30(7):571-84. PMID: 15371093.
      View in: PubMed
    23. Wright RM, Ginger LA, Kosila N, Elkins ND, Essary B, McManaman JL, Repine JE. Mononuclear phagocyte xanthine oxidoreductase contributes to cytokine-induced acute lung injury. Am J Respir Cell Mol Biol. 2004 Apr; 30(4):479-90. PMID: 14512376.
      View in: PubMed
    24. Hybertson BM, Jepson EK, Allard JD, Cho OJ, Lee YM, Huddleston JR, Weinman JP, Oliva AM, Repine JE. Transforming growth factor beta contributes to lung leak in rats given interleukin-1 intratracheally. Exp Lung Res. 2003 Sep; 29(6):361-73. PMID: 12888449.
      View in: PubMed
    25. Park YY, Hybertson BM, Wright RM, Repine JE. Serum ferritin increases in hemorrhaged rats that develop acute lung injury: effect of an iron-deficient diet. Inflammation. 2003 Aug; 27(4):257-63. PMID: 14527178.
      View in: PubMed
    26. Lee YM, Hybertson BM, Cho HG, Repine JE. Platelet-activating factor induces lung inflammation and leak in rats: hydrogen peroxide production along neutrophil-lung endothelial cell interfaces. J Lab Clin Med. 2002 Nov; 140(5):312-9. PMID: 12434132.
      View in: PubMed
    27. Hybertson BM, Connelly KG, Buser RT, Repine JE. Ferritin and desferrioxamine attenuate xanthine oxidase-dependent leak in isolated perfused rat lungs. Inflammation. 2002 Aug; 26(4):153-9. PMID: 12184628.
      View in: PubMed
    28. Zeiher BG, Matsuoka S, Kawabata K, Repine JE. Neutrophil elastase and acute lung injury: prospects for sivelestat and other neutrophil elastase inhibitors as therapeutics. Crit Care Med. 2002 May; 30(5 Suppl):S281-7. PMID: 12004249.
      View in: PubMed
    29. Taravella MJ, Viega J, Luiszer F, Drexler J, Blackburn P, Hovland P, Repine JE. Respirable particles in the excimer laser plume. J Cataract Refract Surg. 2001 Apr; 27(4):604-7. PMID: 11311631.
      View in: PubMed
    30. Hybertson BM, Lee YM, Cho HG, Cho OJ, Repine JE. Alveolar type II cell abnormalities and peroxide formation in lungs of rats given IL-1 intratracheally. Inflammation. 2000 Aug; 24(4):289-303. PMID: 10850852.
      View in: PubMed
    31. Lee YM, Hybertson BM, Cho HG, Terada LS, Cho O, Repine AJ, Repine JE. Platelet-activating factor contributes to acute lung leak in rats given interleukin-1 intratracheally. Am J Physiol Lung Cell Mol Physiol. 2000 Jul; 279(1):L75-80. PMID: 10893205.
      View in: PubMed
    32. Viña J, Gimeno A, Sastre J, Desco C, Asensi M, Pallardó FV, Cuesta A, Ferrero JA, Terada LS, Repine JE. Mechanism of free radical production in exhaustive exercise in humans and rats; role of xanthine oxidase and protection by allopurinol. IUBMB Life. 2000 Jun; 49(6):539-44. PMID: 11032249.
      View in: PubMed
    33. Abraham E, Matthay MA, Dinarello CA, Vincent JL, Cohen J, Opal SM, Glauser M, Parsons P, Fisher CJ, Repine JE. Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. Crit Care Med. 2000 Jan; 28(1):232-5. PMID: 10667529.
      View in: PubMed
    34. Guidot DM, Kitlowski AD, Hybertson BM, Repine JE. Mitochondrial antioxidant function is a potential mechanism for organ differences in interleukin-1-mediated tolerance to oxidative injury. Am J Med Sci. 1999 Nov; 318(5):308-15. PMID: 10555093.
      View in: PubMed
    35. Faust-Chan R, Hybertson B, Flores SC, Wright RM, Repine JE. Initiation and tolerance to acute lung injury: yin-yang mechanisms involving interleukin-1. Chest. 1999 Jul; 116(1 Suppl):102S-103S. PMID: 10424624.
      View in: PubMed
    36. Sharkey RA, Donnelly SC, Connelly KG, Robertson CE, Haslett C, Repine JE. Initial serum ferritin levels in patients with multiple trauma and the subsequent development of acute respiratory distress syndrome. Am J Respir Crit Care Med. 1999 May; 159(5 Pt 1):1506-9. PMID: 10228118.
      View in: PubMed
    37. Linas SL, Repine JE. Endothelial cells regulate proximal tubule epithelial cell sodium transport. Kidney Int. 1999 Apr; 55(4):1251-8. PMID: 10200988.
      View in: PubMed
    38. Wright RM, Clayton DA, Riley MG, McManaman JL, Repine JE. cDNA cloning, sequencing, and characterization of male and female rat liver aldehyde oxidase (rAOX1). Differences in redox status may distinguish male and female forms of hepatic APX. J Biol Chem. 1999 Feb 05; 274(6):3878-86. PMID: 9920943.
      View in: PubMed
    39. Wright RM, McManaman JL, Repine JE. Alcohol-induced breast cancer: a proposed mechanism. Free Radic Biol Med. 1999 Feb; 26(3-4):348-54. PMID: 9895226.
      View in: PubMed
    40. Stringer KA, Hybertson BM, Cho OJ, Cohen Z, Repine JE. Tissue plasminogen activator (tPA) inhibits interleukin-1 induced acute lung leak. Free Radic Biol Med. 1998 Jul 15; 25(2):184-8. PMID: 9667494.
      View in: PubMed
    41. Hybertson BM, Kitlowski RP, Jepson EK, Repine JE. Supercritical fluid-aerosolized vitamin E pretreatment decreases leak in isolated oxidant-perfused rat lungs. J Appl Physiol (1985). 1998 Jan; 84(1):263-8. PMID: 9451645.
      View in: PubMed
    42. Hybertson BM, Lee YM, Repine JE. Phagocytes and acute lung injury: dual roles for interleukin-1. Ann N Y Acad Sci. 1997 Dec 15; 832:266-73. PMID: 9704053.
      View in: PubMed
    43. Guidot DM, Bursten SL, Rice GC, Chaney RB, Singer JW, Repine AJ, Hybertson BM, Repine JE. Modulating phosphatidic acid metabolism decreases oxidative injury in rat lungs. Am J Physiol. 1997 Nov; 273(5 Pt 1):L957-66. PMID: 9374722.
      View in: PubMed
    44. Wright RM, Repine JE. The human molybdenum hydroxylase gene family: co-conspirators in metabolic free-radical generation and disease. Biochem Soc Trans. 1997 Aug; 25(3):799-804. PMID: 9388549.
      View in: PubMed
    45. Repine JE, Bast A, Lankhorst I. Oxidative stress in chronic obstructive pulmonary disease. Oxidative Stress Study Group. Am J Respir Crit Care Med. 1997 Aug; 156(2 Pt 1):341-57. PMID: 9279209.
      View in: PubMed
    46. Linas SL, Repine JE. Endothelial cells protect vascular smooth muscle cells from H2O2 attack. Am J Physiol. 1997 Jun; 272(6 Pt 2):F767-73. PMID: 9227638.
      View in: PubMed
    47. Wright RM, Weigel LK, Varella-Garcia M, Vaitaitis G, Repine JE. Molecular cloning, refined chromosomal mapping and structural analysis of the human gene encoding aldehyde oxidase (AOX1), a candidate for the ALS2 gene. Redox Rep. 1997 Jun; 3(3):135-44. PMID: 27406959.
      View in: PubMed
    48. Hybertson BM, Jepson EK, Cho OJ, Clarke JH, Lee YM, Repine JE. TNF mediates lung leak, but not neutrophil accumulation, in lungs of rats given IL-1 intratracheally. Am J Respir Crit Care Med. 1997 Jun; 155(6):1972-6. PMID: 9196104.
      View in: PubMed
    49. Lee YM, Hybertson BM, Terada LS, Repine AJ, Cho HG, Repine JE. Mepacrine decreases lung leak in rats given interleukin-1 intratracheally. Am J Respir Crit Care Med. 1997 May; 155(5):1624-8. PMID: 9154867.
      View in: PubMed
    50. Parsons PE, Moss M, Vannice JL, Moore EE, Moore FA, Repine JE. Circulating IL-1ra and IL-10 levels are increased but do not predict the development of acute respiratory distress syndrome in at-risk patients. Am J Respir Crit Care Med. 1997 Apr; 155(4):1469-73. PMID: 9105096.
      View in: PubMed
    51. Terada LS, Hybertson BM, Connelly KG, Weill D, Piermattei D, Repine JE. XO increases neutrophil adherence to endothelial cells by a dual ICAM-1 and P-selectin-mediated mechanism. J Appl Physiol (1985). 1997 Mar; 82(3):866-73. PMID: 9074976.
      View in: PubMed
    52. Terada LS, Repine JE, Piermattei D, Hybertson BM. Endogenous nitric oxide decreases xanthine oxidase-mediated neutrophil adherence: role of P-selectin. J Appl Physiol (1985). 1997 Mar; 82(3):913-7. PMID: 9074982.
      View in: PubMed
    53. Stringer KA, Lindenfeld J, Repine AJ, Cohen Z, Repine JE. Tissue plasminogen activator (tPA) inhibits human neutrophil superoxide anion production in vitro. Inflammation. 1997 Feb; 21(1):27-34. PMID: 9179619.
      View in: PubMed
    54. Connelly KG, Moss M, Parsons PE, Moore EE, Moore FA, Giclas PC, Seligman PA, Repine JE. Serum ferritin as a predictor of the acute respiratory distress syndrome. Am J Respir Crit Care Med. 1997 Jan; 155(1):21-5. PMID: 9001283.
      View in: PubMed
    55. Connelly KG, Repine JE. Markers for predicting the development of acute respiratory distress syndrome. Annu Rev Med. 1997; 48:429-45. PMID: 9046974.
      View in: PubMed
    56. Linas S, Whittenburg D, Repine JE. Nitric oxide prevents neutrophil-mediated acute renal failure. Am J Physiol. 1997 Jan; 272(1 Pt 2):F48-54. PMID: 9039048.
      View in: PubMed
    57. Hybertson BM, Bursten SL, Leff JA, Lee YM, Jepson EK, Dewitt CR, Zagorski J, Cho HG, Repine JE. Lisofylline prevents leak, but not neutrophil accumulation, in lungs of rats given IL-1 intratracheally. J Appl Physiol (1985). 1997 Jan; 82(1):226-32. PMID: 9029220.
      View in: PubMed
    58. Koh Y, Hybertson BM, Jepson EK, Repine JE. Tumor necrosis factor induced acute lung leak in rats: less than with interleukin-1. Inflammation. 1996 Oct; 20(5):461-9. PMID: 8894711.
      View in: PubMed
    59. McManaman JL, Shellman V, Wright RM, Repine JE. Purification of rat liver xanthine oxidase and xanthine dehydrogenase by affinity chromatography on benzamidine-sepharose. Arch Biochem Biophys. 1996 Aug 01; 332(1):135-41. PMID: 8806718.
      View in: PubMed
    60. Guidot DM, Hybertson BM, Kitlowski RP, Repine JE. Inhaled NO prevents IL-1-induced neutrophil accumulation and associated acute edema in isolated rat lungs. Am J Physiol. 1996 Aug; 271(2 Pt 1):L225-9. PMID: 8770060.
      View in: PubMed
    61. Bursten SL, Federighi DA, Parsons P, Harris WE, Abraham E, Moore EE, Moore FA, Bianco JA, Singer JW, Repine JE. An increase in serum C18 unsaturated free fatty acids as a predictor of the development of acute respiratory distress syndrome. Crit Care Med. 1996 Jul; 24(7):1129-36. PMID: 8674324.
      View in: PubMed
    62. Hanley ME, Terada LS, Cheronis JC, Repine JE. Endothelial cell associated anti-elastolytic activity. Inflammation. 1996 Jun; 20(3):327-37. PMID: 8796384.
      View in: PubMed
    63. Shenkar R, Schwartz MD, Terada LS, Repine JE, McCord J, Abraham E. Hemorrhage activates NF-kappa B in murine lung mononuclear cells in vivo. Am J Physiol. 1996 May; 270(5 Pt 1):L729-35. PMID: 8967506.
      View in: PubMed
    64. Linas SL, Whittenburg D, Parsons PE, Repine JE. Ischemia increases neutrophil retention and worsens acute renal failure: role of oxygen metabolites and ICAM 1. Kidney Int. 1995 Nov; 48(5):1584-91. PMID: 8544418.
      View in: PubMed
    65. Wright RM, Vaitaitis GM, Weigel LK, Repine TB, McManaman JL, Repine JE. Identification of the candidate ALS2 gene at chromosome 2q33 as a human aldehyde oxidase gene. Redox Rep. 1995 Nov; 1(5):313-21. PMID: 27405828.
      View in: PubMed
    66. Hybertson BM, Lampey AS, Clarke JH, Koh Y, Repine JE. N-acetylcysteine pretreatment attenuates paraquat-induced lung leak in rats. Redox Rep. 1995 Nov; 1(5):337-42. PMID: 27405831.
      View in: PubMed
    67. Wright RM, Weigel LK, Repine JE. Aldehyde oxidase generates deoxyribonucleic acid single strand nicks in vitro. Redox Rep. 1995 Nov; 1(5):349-55. PMID: 27405833.
      View in: PubMed
    68. Smith D, Kirschenheuter GP, Charlton J, Guidot DM, Repine JE. In vitro selection of RNA-based irreversible inhibitors of human neutrophil elastase. Chem Biol. 1995 Nov; 2(11):741-50. PMID: 9383481.
      View in: PubMed
    69. Koh Y, Hybertson BM, Jepson EK, Cho OJ, Repine JE. Cytokine-induced neutrophil chemoattractant is necessary for interleukin-1-induced lung leak in rats. J Appl Physiol (1985). 1995 Aug; 79(2):472-8. PMID: 7592205.
      View in: PubMed
    70. Guidot DM, Repine JE, Kitlowski AD, Flores SC, Nelson SK, Wright RM, McCord JM. Mitochondrial respiration scavenges extramitochondrial superoxide anion via a nonenzymatic mechanism. J Clin Invest. 1995 Aug; 96(2):1131-6. PMID: 7635949; PMCID: PMC185303.
      View in: PubMed, PubMed Central
    71. Guidot DM, Repine MJ, Hybertson BM, Repine JE. Inhaled nitric oxide prevents neutrophil-mediated, oxygen radical-dependent leak in isolated rat lungs. Am J Physiol. 1995 Jul; 269(1 Pt 1):L2-5. PMID: 7631809.
      View in: PubMed
    72. Shapiro JI, Elkins N, Logan J, Ferstenberg LB, Repine JE. Effects of sodium bicarbonate, disodium carbonate, and a sodium bicarbonate/carbonate mixture on the PCO2 of blood in a closed system. J Lab Clin Med. 1995 Jul; 126(1):65-9. PMID: 7602236.
      View in: PubMed
    73. Schwartz MD, Repine JE, Abraham E. Xanthine oxidase-derived oxygen radicals increase lung cytokine expression in mice subjected to hemorrhagic shock. Am J Respir Cell Mol Biol. 1995 Apr; 12(4):434-40. PMID: 7695923.
      View in: PubMed
    74. Berger R, Mezey E, Clancy KP, Harta G, Wright RM, Repine JE, Brown RH, Brownstein M, Patterson D. Analysis of aldehyde oxidase and xanthine dehydrogenase/oxidase as possible candidate genes for autosomal recessive familial amyotrophic lateral sclerosis. Somat Cell Mol Genet. 1995 Mar; 21(2):121-31. PMID: 7570184.
      View in: PubMed
    75. Hybertson BM, Leff JA, Beehler CJ, Barry PC, Repine JE. Effect of vitamin E deficiency and supercritical fluid aerosolized vitamin E supplementation on interleukin-1-induced oxidative lung injury in rats. Free Radic Biol Med. 1995 Mar; 18(3):537-42. PMID: 9101244.
      View in: PubMed
    76. Abraham E, Bursten S, Shenkar R, Allbee J, Tuder R, Woodson P, Guidot DM, Rice G, Singer JW, Repine JE. Phosphatidic acid signaling mediates lung cytokine expression and lung inflammatory injury after hemorrhage in mice. J Exp Med. 1995 Feb 01; 181(2):569-75. PMID: 7836912; PMCID: PMC2191876.
      View in: PubMed, PubMed Central
    77. Burton LK, Velasco SE, Patt A, Terada LS, Repine JE. Xanthine oxidase contributes to lung leak in rats subjected to skin burn. Inflammation. 1995 Feb; 19(1):31-8. PMID: 7705885.
      View in: PubMed
    78. Patton LM, Saggart BS, Ahmed NK, Leff JA, Repine JE. Interleukin-1 beta-induced neutrophil recruitment and acute lung injury in hamsters. Inflammation. 1995 Feb; 19(1):23-9. PMID: 7705884.
      View in: PubMed
    79. Leff JA, Wilke CP, Furman MJ, Bodman ME, Repine JE. Interleukin-1 pretreatment prevents interleukin-1-induced lung leak in rats. Am J Physiol. 1995 Jan; 268(1 Pt 1):L12-6. PMID: 7840217.
      View in: PubMed
    80. Repine JE. Interleukin-1-mediated acute lung injury and tolerance to oxidative injury. Environ Health Perspect. 1994 Dec; 102 Suppl 10:75-8. PMID: 7705311.
      View in: PubMed
    81. Guidot DM, Linas SL, Repine MJ, Shanley PF, Fisher HS, Repine JE. Interleukin-1 treatment increases neutrophils but not antioxidant enzyme activity or resistance to ischemia-reperfusion injury in rat kidneys. Inflammation. 1994 Oct; 18(5):537-45. PMID: 7843798.
      View in: PubMed
    82. Guidot DM, Repine MJ, Westcott JY, Repine JE. Intrinsic 5-lipoxygenase activity is required for neutrophil responsivity. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8156-9. PMID: 8058773; PMCID: PMC44564.
      View in: PubMed, PubMed Central
    83. Leff JA, Bodman ME, Cho OJ, Rohrbach S, Reiss OK, Vannice JL, Repine JE. Post-insult treatment with interleukin-1 receptor antagonist decreases oxidative lung injury in rats given intratracheal interleukin-1. Am J Respir Crit Care Med. 1994 Jul; 150(1):109-12. PMID: 8025734.
      View in: PubMed
    84. Guidot DM, Stevens EE, Repine MJ, Lucca-Broco AE, Repine JE. Intratracheal but not intravascular interleukin-1 causes acute edematous injury in isolated neutrophil-perfused rat lungs through an oxygen radical-mediated mechanism. J Lab Clin Med. 1994 Apr; 123(4):605-9. PMID: 8145009.
      View in: PubMed
    85. Guidot D, Repine JE. Interleukin-1-induced tolerance to IL-1-induced oxidative lung injury in rats. Chest. 1994 Mar; 105(3 Suppl):86S. PMID: 8131624.
      View in: PubMed
    86. Moores HK, Beehler CJ, Hanley ME, Shanley PF, Stevens EE, Repine JE, Terada LS. Xanthine oxidase promotes neutrophil sequestration but not injury in hyperoxic lungs. J Appl Physiol (1985). 1994 Feb; 76(2):941-5. PMID: 8175609.
      View in: PubMed
    87. Beehler CJ, Ely ME, Rutledge KS, Simchuk ML, Reiss OK, Shanley PF, Repine JE. Toxic effects of dimethylthiourea in rats. J Lab Clin Med. 1994 Jan; 123(1):73-80. PMID: 8288964.
      View in: PubMed
    88. Leff JA, Baer JW, Kirkman JM, Bodman ME, Shanley PF, Cho OJ, Ostro MJ, Repine JE. Liposome-entrapped PGE1 posttreatment decreases IL-1 alpha-induced neutrophil accumulation and lung leak in rats. J Appl Physiol (1985). 1994 Jan; 76(1):151-7. PMID: 8175500.
      View in: PubMed
    89. Leff JA, Baer JW, Bodman ME, Kirkman JM, Shanley PF, Patton LM, Beehler CJ, McCord JM, Repine JE. Interleukin-1-induced lung neutrophil accumulation and oxygen metabolite-mediated lung leak in rats. Am J Physiol. 1994 Jan; 266(1 Pt 1):L2-8. PMID: 8304466.
      View in: PubMed
    90. Guidot DM, McCord JM, Wright RM, Repine JE. Absence of electron transport (Rho 0 state) restores growth of a manganese-superoxide dismutase-deficient Saccharomyces cerevisiae in hyperoxia. Evidence for electron transport as a major source of superoxide generation in vivo. J Biol Chem. 1993 Dec 15; 268(35):26699-703. PMID: 8253804.
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    91. Wright RM, Vaitaitis GM, Wilson CM, Repine TB, Terada LS, Repine JE. cDNA cloning, characterization, and tissue-specific expression of human xanthine dehydrogenase/xanthine oxidase. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10690-4. PMID: 8248161; PMCID: PMC47843.
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    92. Leff JA, Wilke CP, Hybertson BM, Shanley PF, Beehler CJ, Repine JE. Postinsult treatment with N-acetyl-L-cysteine decreases IL-1-induced neutrophil influx and lung leak in rats. Am J Physiol. 1993 Nov; 265(5 Pt 1):L501-6. PMID: 8238538.
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    93. Wright RM, Repine T, Repine JE. Reversible pseudohyphal growth in haploid Saccharomyces cerevisiae is an aerobic process. Curr Genet. 1993 May-Jun; 23(5-6):388-91. PMID: 8319293.
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    94. Leff JA, Burton LK, Berger EM, Anderson BO, Wilke CP, Repine JE. Increased serum catalase activity in rats subjected to thermal skin injury. Inflammation. 1993 Apr; 17(2):199-204. PMID: 8491514.
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    95. Leff JA, Parsons PE, Day CE, Taniguchi N, Jochum M, Fritz H, Moore FA, Moore EE, McCord JM, Repine JE. Serum antioxidants as predictors of adult respiratory distress syndrome in patients with sepsis. Lancet. 1993 Mar 27; 341(8848):777-80. PMID: 8095998.
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    96. Hanley ME, Repine JE. Elastase and oxygen radicals: synergistic interactions. Agents Actions Suppl. 1993; 42:39-47. PMID: 8356930.
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    97. Leff JA, Parsons PE, Day CE, Moore EE, Moore FA, Oppegard MA, Repine JE. Increased serum catalase activity in septic patients with the adult respiratory distress syndrome. Am Rev Respir Dis. 1992 Oct; 146(4):985-9. PMID: 1416429.
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    98. Terada LS, Dormish JJ, Shanley PF, Leff JA, Anderson BO, Repine JE. Circulating xanthine oxidase mediates lung neutrophil sequestration after intestinal ischemia-reperfusion. Am J Physiol. 1992 Sep; 263(3 Pt 1):L394-401. PMID: 1329531.
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    99. Linas SL, Whittenburg D, Parsons PE, Repine JE. Mild renal ischemia activates primed neutrophils to cause acute renal failure. Kidney Int. 1992 Sep; 42(3):610-6. PMID: 1405339.
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    100. Leff JA, Oppegard MA, McCarty EC, Wilke CP, Shanley PF, Day CE, Ahmed NK, Patton LM, Repine JE. Dimethyl sulfoxide decreases lung neutrophil sequestration and lung leak. J Lab Clin Med. 1992 Aug; 120(2):282-9. PMID: 1500826.
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    101. Brown JM, Anderson BO, Repine JE, Shanley PF, White CW, Grosso MA, Banerjee A, Bensard DD, Harken AH. Neutrophils contribute to TNF induced myocardial tolerance to ischaemia. J Mol Cell Cardiol. 1992 May; 24(5):485-95. PMID: 1635073.
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    102. Beehler CJ, Simchuk ML, McCord JM, Repine JE. Effects of dimethylthiourea in hyperoxic injury. J Lab Clin Med. 1992 May; 119(5):508-13. PMID: 1583407.
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    103. Terada LS, Guidot DM, Leff JA, Willingham IR, Hanley ME, Piermattei D, Repine JE. Hypoxia injures endothelial cells by increasing endogenous xanthine oxidase activity. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3362-6. PMID: 1314387; PMCID: PMC48867.
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    104. Repine JE. Scientific perspectives on adult respiratory distress syndrome. Lancet. 1992 Feb 22; 339(8791):466-9. PMID: 1346826.
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    105. Terada LS, Willingham IR, Guidot DM, Shibao GN, Kindt GW, Repine JE. Tungsten treatment prevents tumor necrosis factor-induced injury of brain endothelial cells. Inflammation. 1992 Feb; 16(1):13-9. PMID: 1544679.
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    106. Leff JA, Oppegard MA, Curiel TJ, Brown KS, Schooley RT, Repine JE. Progressive increases in serum catalase activity in advancing human immunodeficiency virus infection. Free Radic Biol Med. 1992; 13(2):143-9. PMID: 1516841.
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    107. Anderson BO, Moore EE, Moore FA, Leff JA, Terada LS, Harken AH, Repine JE. Hypovolemic shock promotes neutrophil sequestration in lungs by a xanthine oxidase-related mechanism. J Appl Physiol (1985). 1991 Nov; 71(5):1862-5. PMID: 1662198.
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    108. Leff JA, Oppegard MA, Terada LS, McCarty EC, Repine JE. Human serum catalase decreases endothelial cell injury from hydrogen peroxide. J Appl Physiol (1985). 1991 Nov; 71(5):1903-6. PMID: 1761490.
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    109. Mulvin DW, Jones DK, Howard RB, Grosso MA, Repine JE, Johnston MR. Extracellular flush solution that contains blood, mannitol, albumin, and prostacyclin protects rat lungs from six hours of ischemia. J Heart Lung Transplant. 1991 Nov-Dec; 10(6):986-9. PMID: 1756165.
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    110. Leff JA, Kennedy DA, Terada LS, Emmett M, McCutchan HJ, Walden DL, Repine JE. Reperfusion of ischemic skeletal muscle causes erythrocyte hemolysis and decreases subsequent oxidant-mediated lung injury. J Lab Clin Med. 1991 Oct; 118(4):352-8. PMID: 1940577.
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    111. Repine JE. Oxidant-antioxidant balance: some observations from studies of ischemia-reperfusion in isolated perfused rat hearts. Am J Med. 1991 Sep 30; 91(3C):45S-53S. PMID: 1928211.
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    112. Yohn JJ, Norris DA, Yrastorza DG, Buno IJ, Leff JA, Hake SS, Repine JE. Disparate antioxidant enzyme activities in cultured human cutaneous fibroblasts, keratinocytes, and melanocytes. J Invest Dermatol. 1991 Sep; 97(3):405-9. PMID: 1875041.
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    113. Repine JE, Beehler CJ. Neutrophils and adult respiratory distress syndrome: two interlocking perspectives in 1991. Am Rev Respir Dis. 1991 Aug; 144(2):251-2. PMID: 1859047.
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    114. Terada LS, Willingham IR, Rosandich ME, Leff JA, Kindt GW, Repine JE. Generation of superoxide anion by brain endothelial cell xanthine oxidase. J Cell Physiol. 1991 Aug; 148(2):191-6. PMID: 1652587.
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    115. Carrea FP, Lesnefsky EJ, Repine JE, Shikes RH, Horwitz LD. Reduction of canine myocardial infarct size by a diffusible reactive oxygen metabolite scavenger. Efficacy of dimethylthiourea given at the onset of reperfusion. Circ Res. 1991 Jun; 68(6):1652-9. PMID: 1709840.
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    116. McDonald RJ, Berger EM, Repine JE. Alveolar macrophage antioxidants prevent hydrogen peroxide-mediated lung damage. Am Rev Respir Dis. 1991 May; 143(5 Pt 1):1088-91. PMID: 2024819.
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    117. Ghezzi P, Dinarello CA, Bianchi M, Rosandich ME, Repine JE, White CW. Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells. Cytokine. 1991 May; 3(3):189-94. PMID: 1883957.
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    118. Linas SL, Whittenburg D, Repine JE. Role of neutrophil derived oxidants and elastase in lipopolysaccharide-mediated renal injury. Kidney Int. 1991 Apr; 39(4):618-23. PMID: 2051718.
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    119. Terada LS, Rubinstein JD, Lesnefsky EJ, Horwitz LD, Leff JA, Repine JE. Existence and participation of xanthine oxidase in reperfusion injury of ischemic rabbit myocardium. Am J Physiol. 1991 Mar; 260(3 Pt 2):H805-10. PMID: 2000975.
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    120. Anderson BO, Bensard DD, Brown JM, Repine JE, Shanley PF, Leff JA, Terada LS, Banerjee A, Harken AH. FNLP injures endotoxin-primed rat lung by neutrophil-dependent and -independent mechanisms. Am J Physiol. 1991 Feb; 260(2 Pt 2):R413-20. PMID: 1847603.
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    121. Terada LS, Leff JA, Guidot DM, Willingham IR, Repine JE. Inactivation of xanthine oxidase by hydrogen peroxide involves site-directed hydroxyl radical formation. Free Radic Biol Med. 1991; 10(1):61-8. PMID: 1646751.
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    122. Walden DL, McCutchan HJ, Enquist EG, Schwappach JR, Shanley PF, Reiss OK, Terada LS, Leff JA, Repine JE. Neutrophils accumulate and contribute to skeletal muscle dysfunction after ischemia-reperfusion. Am J Physiol. 1990 Dec; 259(6 Pt 2):H1809-12. PMID: 2260705.
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    123. Berger EM, Beehler CJ, Harada RN, Repine JE. Human phagocytic cells as oxygen metabolite scavengers. Inflammation. 1990 Oct; 14(5):613-9. PMID: 2249888.
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    124. Brown JM, White CW, Terada LS, Grosso MA, Shanley PF, Mulvin DW, Banerjee A, Whitman GJ, Harken AH, Repine JE. Interleukin 1 pretreatment decreases ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 1990 Jul; 87(13):5026-30. PMID: 2367521; PMCID: PMC54254.
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    125. Lesnefsky EJ, Repine JE, Horwitz LD. Deferoxamine pretreatment reduces canine infarct size and oxidative injury. J Pharmacol Exp Ther. 1990 Jun; 253(3):1103-9. PMID: 2359019.
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    126. McCutchan HJ, Schwappach JR, Enquist EG, Walden DL, Terada LS, Reiss OK, Leff JA, Repine JE. Xanthine oxidase-derived H2O2 contributes to reperfusion injury of ischemic skeletal muscle. Am J Physiol. 1990 May; 258(5 Pt 2):H1415-9. PMID: 2110780.
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    127. Terada LS, Leff JA, Guidot DN, Shibao GA, Repine JE. Metals inhibit riboflavin-catalyzed generation of superoxide anion in vitro. Inflammation. 1990 Apr; 14(2):217-21. PMID: 2157664.
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    128. Mulvin D, Jones K, Howard R, Grosso M, Repine J, Johnston M. The effect of prostacyclin as a constituent of a preservation solution in protecting lungs from ischemic injury because of its vasodilatory properties. Transplantation. 1990 Apr; 49(4):828-30. PMID: 2109380.
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    129. Waintrub ML, Terada LS, Beehler CJ, Anderson BO, Leff JA, Repine JE. Xanthine oxidase is increased and contributes to paraquat-induced acute lung injury. J Appl Physiol (1985). 1990 Apr; 68(4):1755-7. PMID: 2347813.
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    130. Linas SL, Whittenburg D, Repine JE. Role of xanthine oxidase in ischemia/reperfusion injury. Am J Physiol. 1990 Mar; 258(3 Pt 2):F711-6. PMID: 2316673.
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    131. Patt A, Horesh IR, Berger EM, Harken AH, Repine JE. Iron depletion or chelation reduces ischemia/reperfusion-induced edema in gerbil brains. J Pediatr Surg. 1990 Feb; 25(2):224-7; discussion 227-8. PMID: 2303992.
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    132. Adler KB, Holden-Stauffer WJ, Repine JE. Oxygen metabolites stimulate release of high-molecular-weight glycoconjugates by cell and organ cultures of rodent respiratory epithelium via an arachidonic acid-dependent mechanism. J Clin Invest. 1990 Jan; 85(1):75-85. PMID: 2153154; PMCID: PMC296389.
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    133. Leff JA, Repine JE. Blood cells and ischemia-reperfusion injury. Blood Cells. 1990; 16(1):183-91; discussion 191-2. PMID: 2190646.
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    134. Terada LS, Leff JA, Repine JE. Measurement of xanthine oxidase in biological tissues. Methods Enzymol. 1990; 186:651-6. PMID: 2233323.
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    135. McDonald RJ, Bruckner LV, Repine JE. Neutrophil elastase augments acute edematous injury in isolated rat lungs perfused with neutrophil cytoplasts. Am Rev Respir Dis. 1989 Dec; 140(6):1825-7. PMID: 2557789.
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    136. Brown JM, Beehler CJ, Berger EM, Grosso MA, Whitman GJ, Terada LS, Leff JA, Harken AH, Repine JE. Albumin decreases hydrogen peroxide and reperfusion injury in isolated rat hearts. Inflammation. 1989 Oct; 13(5):583-9. PMID: 2807521.
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    137. Beehler CJ, Simchuk ML, Toth KM, Drake SK, Parker NB, White CW, Berger EM, Sanderson RJ, Repine JE. Blood sulfhydryl level increases during hyperoxia: a marker of oxidant lung injury. J Appl Physiol (1985). 1989 Sep; 67(3):1070-5. PMID: 2507503.
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    138. Mulvin DW, Grosso MA, Kruse CA, Howard RB, Repine JE, Johnston MR. The role of toxic oxygen metabolites in interleukin-2-induced vascular leak syndrome. Curr Surg. 1989 Sep-Oct; 46(5):396-8. PMID: 2805781.
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    139. Heffner JE, Repine JE. Pulmonary strategies of antioxidant defense. Am Rev Respir Dis. 1989 Aug; 140(2):531-54. PMID: 2669581.
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    140. Gross MA, Viders DE, Brown JM, Mulvin DW, Miles RH, Brentlinger ER, Velasco SE, Crawford TS, Burton LK, Repine JE, et al. Local skin burn causes systemic (lung and kidney) endothelial cell injury reflected by increased circulating and decreased tissue factor VIII-related antigen. Surgery. 1989 Aug; 106(2):310-6; discussion 316-7. PMID: 2503901.
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    141. Grosso MA, Brown JM, Viders DE, Mulvin DW, Banerjee A, Velasco SE, Repine JE, Harken AH. Xanthine oxidase-derived oxygen radicals induce pulmonary edema via direct endothelial cell injury. J Surg Res. 1989 Apr; 46(4):355-60. PMID: 2495387.
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    142. Brown JM, Grosso MA, Whitman GJ, Banerjee A, Terada LS, Repine JE, Harken AH. The coincidence of myocardial reperfusion injury and hydrogen peroxide production in the isolated rat heart. Surgery. 1989 Apr; 105(4):496-501. PMID: 2928952.
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    143. Brown JM, Grosso MA, Terada LS, Whitman GJ, Banerjee A, White CW, Harken AH, Repine JE. Endotoxin pretreatment increases endogenous myocardial catalase activity and decreases ischemia-reperfusion injury of isolated rat hearts. Proc Natl Acad Sci U S A. 1989 Apr; 86(7):2516-20. PMID: 2648406; PMCID: PMC286944.
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    144. Brown JM, Grosso MA, Banerjee A, Whitman GJ, Repine JE, Harken AH. Erythrocyte catalase decreases cardiac reperfusion injury. Curr Surg. 1989 Mar-Apr; 46(2):122-4. PMID: 2736964.
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    145. White CW, Jackson JH, Abuchowski A, Kazo GM, Mimmack RF, Berger EM, Freeman BA, McCord JM, Repine JE. Polyethylene glycol-attached antioxidant enzymes decrease pulmonary oxygen toxicity in rats. J Appl Physiol (1985). 1989 Feb; 66(2):584-90. PMID: 2540139.
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    146. White CW, Ghezzi P, McMahon S, Dinarello CA, Repine JE. Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia. J Appl Physiol (1985). 1989 Feb; 66(2):1003-7. PMID: 2651381.
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    147. Brown JM, Grosso MA, Terada LS, Beehler CJ, Toth KM, Whitman GJ, Harken AH, Repine JE. Erythrocytes decrease myocardial hydrogen peroxide levels and reperfusion injury. Am J Physiol. 1989 Feb; 256(2 Pt 2):H584-8. PMID: 2916691.
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    148. Toth KM, Harlan JM, Beehler CJ, Berger EM, Parker NB, Linas SL, Repine JE. Dimethylthiourea prevents hydrogen peroxide and neutrophil mediated damage to lung endothelial cells in vitro and disappears in the process. Free Radic Biol Med. 1989; 6(5):457-66. PMID: 2545552.
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    149. Lesnefsky EJ, Repine JE, Horwitz LD. Oxidation and release of glutathione from myocardium during early reperfusion. Free Radic Biol Med. 1989; 7(1):31-5. PMID: 2753394.
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    150. Portz SJ, Lesnefsky EJ, VanBenthuysen KM, Repine JE, Parker NB, McMurtry IF, Horwitz LD. Dimethylthiourea, but not dimethylsulfoxide, reduces canine myocardial infarct size. Free Radic Biol Med. 1989; 7(1):53-8. PMID: 2502484.
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    151. White CW, Jackson JH, McMurtry IF, Repine JE. Hypoxia increases glutathione redox cycle and protects rat lungs against oxidants. J Appl Physiol (1985). 1988 Dec; 65(6):2607-16. PMID: 3215862.
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    152. Brown JM, Terada LS, Grosso MA, Whitman GJ, Velasco SE, Patt A, Harken AH, Repine JE. Hydrogen peroxide mediates reperfusion injury in the isolated rat heart. Mol Cell Biochem. 1988 Dec; 84(2):173-5. PMID: 3148110.
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    153. Terada LS, Beehler CJ, Banerjee A, Brown JM, Grosso MA, Harken AH, McCord JM, Repine JE. Hyperoxia and self- or neutrophil-generated O2 metabolites inactivate xanthine oxidase. J Appl Physiol (1985). 1988 Nov; 65(5):2349-53. PMID: 3209579.
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    154. Berger EM, Shibao GA, Brown SN, Repine JE. Variable effect of toxic shock toxins from different sources on neutrophil function in vitro. Inflammation. 1988 Oct; 12(5):447-53. PMID: 2848768.
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    155. Linas SL, Shanley PF, Whittenburg D, Berger E, Repine JE. Neutrophils accentuate ischemia-reperfusion injury in isolated perfused rat kidneys. Am J Physiol. 1988 Oct; 255(4 Pt 2):F728-35. PMID: 2845813.
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    156. Jackson JH, Berger EM, Repine JE. Thiourea and dimethylthiourea decrease human neutrophil bactericidal function in vitro. Inflammation. 1988 Oct; 12(5):515-24. PMID: 2848772.
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    157. Brown JM, Grosso MA, Whitman GJ, Terada LS, Repine JE, Harken AH. Cardiac oxidase systems mediate oxygen metabolite reperfusion injury. Surgery. 1988 Aug; 104(2):266-71. PMID: 3135626.
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    158. Beckman JS, Minor RL, White CW, Repine JE, Rosen GM, Freeman BA. Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance. J Biol Chem. 1988 May 15; 263(14):6884-92. PMID: 3129432.
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    159. Curtis WE, Muldrow ME, Parker NB, Barkley R, Linas SL, Repine JE. N,N'-dimethylthiourea dioxide formation from N,N'-dimethylthiourea reflects hydrogen peroxide concentrations in simple biological systems. Proc Natl Acad Sci U S A. 1988 May; 85(10):3422-5. PMID: 3130627; PMCID: PMC280223.
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    160. Blaser MJ, Smith PF, Repine JE, Joiner KA. Pathogenesis of Campylobacter fetus infections. Failure of encapsulated Campylobacter fetus to bind C3b explains serum and phagocytosis resistance. J Clin Invest. 1988 May; 81(5):1434-44. PMID: 3366901; PMCID: PMC442575.
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    161. Morel DR, Lowenstein E, Nguyenduy T, Robinson DR, Repine JE, Chenoweth DE, Zapol WM. Acute pulmonary vasoconstriction and thromboxane release during protamine reversal of heparin anticoagulation in awake sheep. Evidence for the role of reactive oxygen metabolites following nonimmunological complement activation. Circ Res. 1988 May; 62(5):905-15. PMID: 3129208.
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    162. Brown JM, Terada LS, Grosso MA, Whitmann GJ, Velasco SE, Patt A, Harken AH, Repine JE. Xanthine oxidase produces hydrogen peroxide which contributes to reperfusion injury of ischemic, isolated, perfused rat hearts. J Clin Invest. 1988 Apr; 81(4):1297-301. PMID: 3127425; PMCID: PMC329662.
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    163. Berger EM, Murphy K, Shibao GA, Repine JE. Small increases in pH decrease uptake of Escherichia coli by human neutrophils in vitro. Inflammation. 1988 Apr; 12(2):161-7. PMID: 2839421.
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    164. Rodell TC, Cheronis JC, Repine JE. Endothelial cell xanthine oxidase-derived toxic oxygen metabolites contribute to acute lung injury from neutrophil elastase. Chest. 1988 Mar; 93(3 Suppl):146S. PMID: 3342692.
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    165. Rodell TC, Cheronis JC, Ohnemus CL, Piermattei DJ, Repine JE. Xanthine oxidase mediates elastase-induced injury to isolated lungs and endothelium. J Appl Physiol (1985). 1987 Nov; 63(5):2159-63. PMID: 2826385.
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    166. Stelzner TJ, Welsh CH, Berger E, McCullough RG, Morris K, Repine JE, Weil JV. Antiarrhythmic agents diminish thiourea-induced pulmonary vascular protein leak in rats. J Appl Physiol (1985). 1987 Nov; 63(5):1877-83. PMID: 3121576.
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    167. Linas SL, Whittenburg D, Repine JE. O2 metabolites cause reperfusion injury after short but not prolonged renal ischemia. Am J Physiol. 1987 Oct; 253(4 Pt 2):F685-91. PMID: 3116859.
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    168. Linas SL, Shanley PF, White CW, Parker NP, Repine JE. O2 metabolite-mediated injury in perfused kidneys is reflected by consumption of DMTU and glutathione. Am J Physiol. 1987 Oct; 253(4 Pt 2):F692-701. PMID: 2821829.
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    169. Repine JE, Cheronis JC, Rodell TC, Linas SL, Patt A. Pulmonary oxygen toxicity and ischemia-reperfusion injury. A mechanism in common involving xanthine oxidase and neutrophils. Am Rev Respir Dis. 1987 Aug; 136(2):483-5. PMID: 3619213.
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    170. Brigham KL, Meyrick B, Berry LC, Repine JE. Antioxidants protect cultured bovine lung endothelial cells from injury by endotoxin. J Appl Physiol (1985). 1987 Aug; 63(2):840-50. PMID: 3654444.
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    171. Bolli R, Zhu WX, Hartley CJ, Michael LH, Repine JE, Hess ML, Kukreja RC, Roberts R. Attenuation of dysfunction in the postischemic 'stunned' myocardium by dimethylthiourea. Circulation. 1987 Aug; 76(2):458-68. PMID: 3111744.
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    172. White CW, Ghezzi P, Dinarello CA, Caldwell SA, McMurtry IF, Repine JE. Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia. J Clin Invest. 1987 Jun; 79(6):1868-73. PMID: 3495553; PMCID: PMC424531.
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    173. Patt A, Rutherford RB, Pearce WH, Repine JE. Cerebral ischemia-reperfusion injury in the gerbil. J Surg Res. 1987 May; 42(5):462-6. PMID: 3586621.
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    174. McDonald RJ, Berger EM, Repine JE. Neutrophil-derived oxygen metabolites stimulate thromboxane release, pulmonary artery pressure increases, and weight gains in isolated perfused rat lungs. Am Rev Respir Dis. 1987 Apr; 135(4):957-9. PMID: 3565946.
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    175. Heffner JE, Sahn SA, Repine JE. The role of platelets in the adult respiratory distress syndrome. Culprits or bystanders? Am Rev Respir Dis. 1987 Feb; 135(2):482-92. PMID: 3813208.
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    176. Baird BR, Cheronis JC, Sandhaus RA, Berger EM, White CW, Repine JE. O2 metabolites and neutrophil elastase synergistically cause edematous injury in isolated rat lungs. J Appl Physiol (1985). 1986 Dec; 61(6):2224-9. PMID: 3643211.
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    177. Berger EM, Lockey JE, Aldrich VH, Repine JE. Increased incidence of menstruation-associated bactericidal defects in neutrophils from women who have recovered from toxic shock syndrome. Inflammation. 1986 Dec; 10(4):471-80. PMID: 3025096.
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    178. Berger EM, Beehler CJ, Repine JE. Persistent bactericidal defect in neutrophils from a young woman who recovered from toxic shock syndrome. Inflammation. 1986 Dec; 10(4):463-9. PMID: 3025095.
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    179. Toth KM, Berger EM, Beehler CJ, Repine JE. Erythrocytes from cigarette smokers contain more glutathione and catalase and protect endothelial cells from hydrogen peroxide better than do erythrocytes from nonsmokers. Am Rev Respir Dis. 1986 Aug; 134(2):281-4. PMID: 3740654.
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    180. Jackson JH, White CW, McMurtry IF, Berger EM, Repine JE. Dimethylthiourea decreases acute lung edema in phorbol myristate acetate-treated rabbits. J Appl Physiol (1985). 1986 Jul; 61(1):353-60. PMID: 3090013.
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    181. Douvas GS, Berger EM, Repine JE, Crowle AJ. Natural mycobacteriostatic activity in human monocyte-derived adherent cells. Am Rev Respir Dis. 1986 Jul; 134(1):44-8. PMID: 3014936.
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    182. White CW, Mimmack RF, Repine JE. Accumulation of lung tissue oxidized glutathione (GSSG) as a marker of oxidant induced lung injury. Chest. 1986 Mar; 89(3 Suppl):111S-113S. PMID: 3948571.
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    183. Jackson JH, White CW, Parker NB, Ryan JW, Repine JE. Dimethylthiourea consumption reflects H2O2 concentrations and severity of acute lung injury. J Appl Physiol (1985). 1985 Dec; 59(6):1995-8. PMID: 3001019.
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    184. Antony VB, Sahn SA, Antony AC, Repine JE. Bacillus Calmette-Guérin-stimulated neutrophils release chemotaxins for monocytes in rabbit pleural spaces and in vitro. J Clin Invest. 1985 Oct; 76(4):1514-21. PMID: 3902892; PMCID: PMC424118.
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    185. McDonald RJ, Berger EM, White CW, White JG, Freeman BA, Repine JE. Effect of superoxide dismutase encapsulated in liposomes or conjugated with polyethylene glycol on neutrophil bactericidal activity in vitro and bacterial clearance in vivo. Am Rev Respir Dis. 1985 Apr; 131(4):633-7. PMID: 3994159.
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    186. Bowman CM, Berger EM, Butler EN, Toth KM, Repine JE. HEPES may stimulate cultured endothelial cells to make growth-retarding oxygen metabolites. In Vitro Cell Dev Biol. 1985 Mar; 21(3 Pt 1):140-2. PMID: 4008430.
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    187. Harada RN, Repine JE. Pulmonary host defense mechanisms. Chest. 1985 Feb; 87(2):247-52. PMID: 3881229.
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    188. White CW, Repine JE. Pulmonary antioxidant defense mechanisms. Exp Lung Res. 1985; 8(2-3):81-96. PMID: 3928342.
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    189. Parker NB, Berger EM, Curtis WE, Muldrow ME, Linas SL, Repine JE. Hydrogen peroxide causes dimethylthiourea consumption while hydroxyl radical causes dimethyl sulfoxide consumption in vitro. J Free Radic Biol Med. 1985; 1(5-6):415-9. PMID: 3018065.
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    190. Tate RM, Morris HG, Schroeder WR, Repine JE. Oxygen metabolites stimulate thromboxane production and vasoconstriction in isolated saline-perfused rabbit lungs. J Clin Invest. 1984 Aug; 74(2):608-13. PMID: 6547730; PMCID: PMC370513.
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    191. Toth KM, Clifford DP, Berger EM, White CW, Repine JE. Intact human erythrocytes prevent hydrogen peroxide-mediated damage to isolated perfused rat lungs and cultured bovine pulmonary artery endothelial cells. J Clin Invest. 1984 Jul; 74(1):292-5. PMID: 6330176; PMCID: PMC425212.
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    192. Harada RN, Vatter AE, Repine JE. Macrophage effector function in pulmonary oxygen toxicity: hyperoxia damages and stimulates alveolar macrophages to make and release chemotaxins for polymorphonuclear leukocytes. J Leukoc Biol. 1984 Apr; 35(4):373-83. PMID: 6584527.
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    193. Berger EM, Harada RN, Vatter AE, Bowman CM, Repine JE. Cyclical abnormalities in the bactericidal function, superoxide production, and lysozyme activity of neutrophils obtained from a healthy woman during menstruation: reversal by pretreatment with aspirin. J Infect Dis. 1984 Mar; 149(3):413-9. PMID: 6325550.
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    194. Clifford DP, Rasp FL, Repine JE. Simultaneous measurement of adherence and chemiluminescence by polymorphonuclear leukocytes. Inflammation. 1984 Mar; 8(1):101-6. PMID: 6715029.
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    195. Repine JE, Johansen KS, Berger EM. Hydroxyl radical scavengers produce similar decreases in the chemiluminescence responses and bactericidal activities of neutrophils. Infect Immun. 1984 Jan; 43(1):435-7. PMID: 6317572; PMCID: PMC263455.
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    196. Clifford DP, Repine JE. Measurement of oxidizing radicals by polymorphonuclear leukocytes. Methods Enzymol. 1984; 105:393-8. PMID: 6328192.
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    197. Shoemaker SA, Heffner JE, Canham EM, Tate RM, Morris HG, McMurtry IF, Repine JE. Staphylococcus aureus and human platelets cause pulmonary hypertension and thromboxane generation in isolated saline-perfused rabbit lungs. Am Rev Respir Dis. 1984 Jan; 129(1):92-5. PMID: 6703490.
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    198. Johansen KS, Berger EM, Repine JE. Effect of temperature on polymorphonuclear leukocyte function. Acta Pathol Microbiol Immunol Scand C. 1983 Dec; 91(6):355-9. PMID: 6324534.
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    199. Bowman CM, Harada RN, Repine JE. Hyperoxia stimulates alveolar macrophages to produce and release a factor which increases neutrophil adherence. Inflammation. 1983 Dec; 7(4):331-8. PMID: 6360888.
      View in: PubMed
    200. Antony VB, Sahn SA, Repine JE. Dimethyl sulfoxide inhibits phagocyte influx into infected pleural spaces and phagocyte locomotion in vitro. Inflammation. 1983 Dec; 7(4):377-85. PMID: 6654475.
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    201. Fox RB, Harada RN, Tate RM, Repine JE. Prevention of thiourea-induced pulmonary edema by hydroxyl-radical scavengers. J Appl Physiol Respir Environ Exerc Physiol. 1983 Nov; 55(5):1456-9. PMID: 6417079.
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    202. Harada RN, Vatter AE, Repine JE. Oxygen radical scavengers protect alveolar macrophages from hyperoxic injury in vitro. Am Rev Respir Dis. 1983 Oct; 128(4):761-2. PMID: 6414352.
      View in: PubMed
    203. Bowman CM, Butler EN, Repine JE. Hyperoxia damages cultured endothelial cells causing increased neutrophil adherence. Am Rev Respir Dis. 1983 Sep; 128(3):469-72. PMID: 6614640.
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    204. Tate RM, Repine JE. Neutrophils and the adult respiratory distress syndrome. Am Rev Respir Dis. 1983 Sep; 128(3):552-9. PMID: 6351681.
      View in: PubMed
    205. Repine JE, Tate RM. Oxygen radicals and lung edema. Physiologist. 1983 Jun; 26(3):177-81. PMID: 6351124.
      View in: PubMed
    206. Heffner JE, Shoemaker SA, Canham EM, Patel M, McMurtry IF, Morris HG, Repine JE. Platelet-induced pulmonary hypertension and edema. A mechanism involving acetyl glyceryl ether phosphorylcholine and thromboxane A2. Chest. 1983 May; 83(5 Suppl):78S-79S. PMID: 6839854.
      View in: PubMed
    207. Bowman CM, Butler EN, Vatter AE, Repine JE. Hyperoxia injuries endothelial cells in culture and causes increased neutrophil adherence. Chest. 1983 May; 83(5 Suppl):33S-35S. PMID: 6839844.
      View in: PubMed
    208. Tate RM, Repine JE. Hydrogen peroxide causes permeability edema and hypertension in isolated salt-perfused rabbit lungs. Chest. 1983 May; 83(5 Suppl):48S-50S. PMID: 6687708.
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    209. Antony VB, Repine JE, Harada RN, Good JT, Sahn SA. Inflammatory responses in experimental tuberculosis pleurisy. Acta Cytol. 1983 May-Jun; 27(3):355-61. PMID: 6346774.
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    210. Canham EM, Shoemaker SA, Tate RM, Harada RN, McMurtry IF, Repine JE. Mepacrine but not methylprednisolone decreases acute edematous lung injury after injection of phorbol myristate acetate in rabbits. Am Rev Respir Dis. 1983 May; 127(5):594-8. PMID: 6846941.
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    211. Antony VB, Sahn SA, Harada RN, Repine JE. Lung repair and granuloma formation. Tubercle bacilli stimulated neutrophils release chemotactic factors for monocytes. Chest. 1983 May; 83(5 Suppl):95S-96S. PMID: 6340989.
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    212. Heffner JE, Shoemaker SA, Canham EM, Patel M, McMurtry IF, Morris HG, Repine JE. Acetyl glyceryl ether phosphorylcholine-stimulated human platelets cause pulmonary hypertension and edema in isolated rabbit lungs. Role of thromboxane A2. J Clin Invest. 1983 Feb; 71(2):351-7. PMID: 6822668; PMCID: PMC436874.
      View in: PubMed, PubMed Central
    213. Repine JE, Fox RB, Berger EM. Effect of dimethyl sulfoxide on the bactericidal function of polymorphonuclear leukocytes. Ann N Y Acad Sci. 1983; 411:11-3. PMID: 6576687.
      View in: PubMed
    214. Antony VB, Sahn SA, Repine JE. Effect of dimethyl sulfoxide on chemotaxis of phagocytic cells. Ann N Y Acad Sci. 1983; 411:321-3. PMID: 6576705.
      View in: PubMed
    215. Clifford DP, Repine JE. Hydrogen peroxide mediated killing of bacteria. Mol Cell Biochem. 1982 Dec 10; 49(3):143-9. PMID: 6298593.
      View in: PubMed
    216. Tate RM, Vanbenthuysen KM, Shasby DM, McMurtry IF, Repine JE. Oxygen-radical-mediated permeability edema and vasoconstriction in isolated perfused rabbit lungs. Am Rev Respir Dis. 1982 Nov; 126(5):802-6. PMID: 7149444.
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    217. Davies SF, Clifford DP, Hoidal JR, Repine JE. Opsonic requirements for the uptake of Cryptococcus neoformans by human polymorphonuclear leukocytes and monocytes. J Infect Dis. 1982 Jun; 145(6):870-4. PMID: 7045251.
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    218. Shasby DM, Fox RB, Harada RN, Repine JE. Reduction of the edema of acute hyperoxic lung injury by granulocyte depletion. J Appl Physiol Respir Environ Exerc Physiol. 1982 May; 52(5):1237-44. PMID: 7096148.
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    219. Smith CM, Tukey DP, Mundshenk D, Krivit W, White JG, Repine JE, Hoidal JR. Filtration deformability of rabbit pulmonary macrophage. J Lab Clin Med. 1982 Apr; 99(4):568-79. PMID: 7038013.
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    220. Shasby DM, Vanbenthuysen KM, Tate RM, Shasby SS, McMurtry I, Repine JE. Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicals. Am Rev Respir Dis. 1982 Apr; 125(4):443-7. PMID: 7073114.
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    221. Johansen KS, Borregaard N, Koch C, Taudorf E, Wandall JH, Repine JE. Chronic granulomatous disease presenting as xanthogranulomatous pyelonephritis in late childhood. J Pediatr. 1982 Jan; 100(1):98-100. PMID: 6799633.
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    222. Shasby DM, Shasby SS, Bowman CM, Fox RB, Harada RM, Tate RM, Repine JE. Angiotensin converting enzyme concentrations in the lung lavage of normal rabbits and rabbits treated with nitrogen mustard exposed to hyperoxia. Am Rev Respir Dis. 1981 Aug; 124(2):202-3. PMID: 6266299.
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    223. Hof DG, Repine JE, Giebink GS, Hoidal JR. Production of opsonins that facilitate phagocytosis of Streptococcus pneumoniae by human alveolar macrophages or neutrophils after vaccination with pneumococcal polysaccharide. Am Rev Respir Dis. 1981 Aug; 124(2):193-5. PMID: 7258831.
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    224. Repine JE, Fox RB, Berger EM. Hydrogen peroxide kills Staphylococcus aureus by reacting with staphylococcal iron to form hydroxyl radical. J Biol Chem. 1981 Jul 25; 256(14):7094-6. PMID: 6265438.
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    225. Repine JE, Fox RB, Berger EM, Vatter A, Shasby DM, Bowman CM, Harada RN. Potential mechanisms of lung injury from hydroxyl radical. Chest. 1981 Jul; 80(1 Suppl):45-8. PMID: 6265148.
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    226. Fox RB, Shasby DM, Harada RN, Repine JE. A novel mechanism for pulmonary oxygen toxicity: phagocyte mediated lung injury. Chest. 1981 Jul; 80(1 Suppl):3-4. PMID: 7249731.
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    227. Rasp FL, Sarosi GA, Repine JE. Serum from patients with invasive fungal infections inhibits the adherence of polymorphonuclear leukocytes and alveolar macrophages. Am Rev Respir Dis. 1981 Jun; 123(6):636-9. PMID: 7271060.
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    228. Rasp FL, Clawson CC, Repine JE. Platelets increase neutrophil adherence in vitro to nylon fiber. J Lab Clin Med. 1981 Jun; 97(6):812-9. PMID: 7229512.
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    229. Fox RB, Hoidal JR, Brown DM, Repine JE. Pulmonary inflammation due to oxygen toxicity: involvement of chemotactic factors and polymorphonuclear leukocytes. Am Rev Respir Dis. 1981 May; 123(5):521-3. PMID: 7235375.
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    230. Repine JE, Fox RB, Berger EM, Harada RN. Effect of staphylococcal iron content on the killing of Staphylococcus aureus by polymorphonuclear leukocytes. Infect Immun. 1981 Apr; 32(1):407-10. PMID: 7216492; PMCID: PMC350637.
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    231. Repine JE, Pfenninger OW, Talmage DW, Berger EM, Pettijohn DE. Dimethyl sulfoxide prevents DNA nicking mediated by ionizing radiation or iron/hydrogen peroxide-generated hydroxyl radical. Proc Natl Acad Sci U S A. 1981 Feb; 78(2):1001-3. PMID: 6940118; PMCID: PMC319933.
      View in: PubMed, PubMed Central
    232. Repine JE, Fox RB, Berger EM. Dimethyl sulfoxide inhibits killing of Staphylococcus aureus by polymorphonuclear leukocytes. Infect Immun. 1981 Jan; 31(1):510-3. PMID: 6260668; PMCID: PMC351813.
      View in: PubMed, PubMed Central
    233. Hoidal JR, Fox RB, LeMarbe PA, Perri R, Repine JE. Altered oxidative metabolic responses in vitro of alveolar macrophages from asymptomatic cigarette smokers. Am Rev Respir Dis. 1981 Jan; 123(1):85-9. PMID: 6257154.
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    234. Repine JE, Clawson CC, Goetz FC. Bactericidal function of neutrophils from patients with acute bacterial infections and from diabetics. J Infect Dis. 1980 Dec; 142(6):869-75. PMID: 7007524.
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    235. Hoidal JR, Fox RB, LeMarbre PA, Takiff HE, Repine JE. Oxidative metabolism of alveolar macrophages from young asymptomatic cigarette smokers. Increased superoxide anion release and its potential consequences. Chest. 1980 Feb; 77(2 Suppl):270-1. PMID: 6244133.
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    236. Hof DG, Repine JE, Peterson PK, Hoidal JR. Phagocytosis by human alveolar macrophages and neutrophils: qualitative differences in the opsonic requirements for uptake of Staphylococcus aureus and Streptococcus pneumoniae in vitro. Am Rev Respir Dis. 1980 Jan; 121(1):65-71. PMID: 7352714.
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    237. Repine JE, Eaton JW, Anders MW, Hoidal JR, Fox RB. Generation of hydroxyl radical by enzymes, chemicals, and human phagocytes in vitro. Detection with the anti-inflammatory agent, dimethyl sulfoxide. J Clin Invest. 1979 Dec; 64(6):1642-51. PMID: 500830; PMCID: PMC371318.
      View in: PubMed, PubMed Central
    238. Hoidal JR, Beall GD, Repine JE. Production of hydroxyl radical by human alveolar macrophages. Infect Immun. 1979 Dec; 26(3):1088-92. PMID: 528049; PMCID: PMC414731.
      View in: PubMed, PubMed Central
    239. Clawson CC, Nesbit ME, White JG, Repine JE. Quantitation of chemotaxis and maximal bactericidal capacity of mature neutrophils in chronic myelogenous leukemia. J Reticuloendothel Soc. 1979 Nov; 26(5):515-23. PMID: 292792.
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    240. Hoidal JR, Fox RB, Repine JE. Defective oxidative metabolic responses in vitro of alveolar macrophages in chronic granulomatous disease. Am Rev Respir Dis. 1979 Sep; 120(3):613-8. PMID: 484935.
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    241. Hoidal JR, White JG, Repine JE. Influence of cationic local anesthetics on the metabolism and ultrastructure of human alveolar macrophages. J Lab Clin Med. 1979 May; 93(5):857-66. PMID: 219125.
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    242. Repine JE, Rasmussen B, White JG. An improved nitroblue tetrazolium test using phorbol myristate acetate-coated coverslips. Am J Clin Pathol. 1979 May; 71(5):582-5. PMID: 453076.
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    243. Clawson CC, Repine JE, White JG. The Chediak-Higashi syndrome: quantitation of a deficiency in maximal bactericidal capacity. Am J Pathol. 1979 Mar; 94(3):539-47. PMID: 106731; PMCID: PMC2042259.
      View in: PubMed, PubMed Central
    244. Repine JE, Davies SF, Hoidal JR, Friend PS. Effect of C2-deficiency on the bactericidal activity and chemiluminescence responses of human neutrophils in vitro. Chest. 1979 Feb; 75(2 Suppl):252-4. PMID: 374014.
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    245. Hoidal JR, White JG, Repine JE. Impairment of human alveolar macrophage oxygen consumption, and superoxide anion production by local anesthetics used in bronchoscopy. Chest. 1979 Feb; 75(2 Suppl):243-6. PMID: 219995.
      View in: PubMed
    246. Rasp FL, Clawson CC, Hoidal JR, Repine JE. Quantitation and scanning electron microscopic comparison of human alveolar macrophage and polymorphonuclear leukocyte adherence to nylon fibers in vitro. J Reticuloendothel Soc. 1979 Jan; 25(1):101-9. PMID: 430466.
      View in: PubMed
    247. Rasp FL, Clawson CC, Hoidal JR, Repine JE. Reversible impairment of the adherence of alveolar macrophages from cigarette smokers. Am Rev Respir Dis. 1978 Dec; 118(6):979-86. PMID: 742762.
      View in: PubMed
    248. Hoidal JR, Beall GD, Rasp FL, Holmes B, White JG, Repine JE. Comparison of the metabolism of alveolar macrophages from humans, rats, and rabbits: phorbol myristate acetate. J Lab Clin Med. 1978 Nov; 92(5):787-94. PMID: 712210.
      View in: PubMed
    249. Clawson CC, White JG, Repine JE. The Chédiak-Higashi syndrome. Evidence that defective leukotaxis is primarily due to an impediment by giant granules. Am J Pathol. 1978 Sep; 92(3):745-53. PMID: 686156; PMCID: PMC2018262.
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    250. Repine JE, Clawson CC. Influence of surface proteins and separation techniques on neutrophil unstimulated and stimulated locomotion in vitro. J Reticuloendothel Soc. 1978 Sep; 24(3):217-26. PMID: 366132.
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    251. Repine JE, Clawson CC, Rasp FL, Sarosi GA, Roidal JR. Defective neutrophil locomotion in human blastomycosis: evidence for a serum inhibitor. Am Rev Respir Dis. 1978 Aug; 118(2):325-34. PMID: 697183.
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    252. Hoidal JR, Repine JE, Beall GD, Rasp FL, White JG. The effect of phorbol myristate acetate on the metabolism and ultrastructure of human alveolar macrophages. Am J Pathol. 1978 Jun; 91(3):469-82. PMID: 207188; PMCID: PMC2018315.
      View in: PubMed, PubMed Central
    253. White JG, Repine JE. Fine structural alterations induced in erythocytes by phorbol myristate acetate. Am J Pathol. 1978 Jun; 91(3):571-80. PMID: 655263; PMCID: PMC2018318.
      View in: PubMed, PubMed Central
    254. Repine JE, Rao G, Beall GD, White JG. Inhibition of human neutrophil oxidative metabolism and degranulation in vitro by nitroblue tetrazolium and vitamin E. Am J Pathol. 1978 Mar; 90(3):659-74. PMID: 629327; PMCID: PMC2018253.
      View in: PubMed, PubMed Central
    255. Repine JE, Douglas SD. Effect of levamisole on morphology, bactericidal activity, and metabolism of human neutrophils in vitro. Proc Soc Exp Biol Med. 1977 Dec; 156(3):527-30. PMID: 594083.
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    256. Repine JE, Clawson CC. Quantitative measurement of the bactericidal capability of neutrophils from patients and carriers of chronic granulomatous disease. J Lab Clin Med. 1977 Sep; 90(3):522-8. PMID: 408453.
      View in: PubMed
    257. Beall GD, Repine JE, Hoidal JR, Rasp FL. Chemiluminescence by human alveolar macrophages: stimulation with heat-killed bacteria or phorobol myristate acetate. Infect Immun. 1977 Jul; 17(1):117-20. PMID: 885610; PMCID: PMC421090.
      View in: PubMed, PubMed Central
    258. Repine JE, Clawson CC, Friend PS. Influence of a deficiency of the second component of complement on the bactericidal activity of neutrophils in vitro. J Clin Invest. 1977 May; 59(5):802-9. PMID: 323290; PMCID: PMC372288.
      View in: PubMed, PubMed Central
    259. Repine JE, Clawson CC, Brunning RD. Abnormal pattern of bactericidal activity of neutrophils deficient in granules, myeloperoxidase, and alkaline phosphatase. J Lab Clin Med. 1976 Nov; 88(5):788-95. PMID: 185307.
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    260. Repine JE, Clawson CC, Burchell HB, White JG. Reversible neutrophil defect in patients with bacterial endocarditis. J Lab Clin Med. 1976 Nov; 88(5):780-7. PMID: 978041.
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    261. Repine JE, Clawson CC, Brunning RD. Primary leucocyte alkaline phosphatase deficiency in an adult with repeated infections. Br J Haematol. 1976 Sep; 34(1):87-94. PMID: 952772.
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    262. Clawson CC, Repine JE. Quantitation of maximal bactericidal capability in human neutrophils. J Lab Clin Med. 1976 Aug; 88(2):316-27. PMID: 956687.
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    263. Friend P, Repine JE, Clawson CC, Michael AF. Deficiency of the second component of complement (C2) with chronic vasculitis. Ann Intern Med. 1975 Dec; 83(6):813-6. PMID: 1200526.
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    264. Repine JE, Clawson CC, White JG, Holmes B. Spectrum of function of neutrophils from carriers of sex-linked chronic granulomatous disease. J Pediatr. 1975 Dec; 87(6 Pt 1):901-7. PMID: 1185391.
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    265. Clawson CC, Repine JE. Proceedings: Products of platelet aggregation and release as a chemotactic factor for human leucocytes. Thromb Diath Haemorrh. 1975 Nov 15; 34(2):603. PMID: 1198526.
      View in: PubMed
    266. Repine JE, White JG, Clawson CC, Holmes BH. The influence of phorbol myristate acetate on the metabolism of neutrophils from carriers of sex-linked chronic granulomatous disease. J Lab Clin Med. 1975 Jan; 85(1):82-6. PMID: 1141733.
      View in: PubMed
    267. Repine JE, White JG, Clawson CC, Holmes BM. Effects of phorbol myristate acetate on the metabolism and ultrastructure of neutrophils in chronic granulomatous disease. J Clin Invest. 1974 Jul; 54(1):83-90. PMID: 4366245; PMCID: PMC301526.
      View in: PubMed, PubMed Central
    268. Repine JE, White JG, Clawson CC, Holmes BM. The influence of phorbol myristate acetate on oxygen consumption by polymorphonuclear leukocytes. J Lab Clin Med. 1974 Jun; 83(6):911-20. PMID: 4421315.
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