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Krishna MG Mallela

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOP-Administration
Phone303/724-3576
ORCID ORCID Icon0000-0001-8308-5318 Additional info

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Patrick C, Upadhyay V, Lucas A, Mallela KMG. Biophysical Fitness Landscape of the SARS-CoV-2 Delta Variant Receptor Binding Domain. J Mol Biol. 2022 Jul 15; 434(13):167622. PMID: 35533762.
      View in: PubMed
    2. Upadhyay V, Patrick C, Lucas A, Mallela KMG. Convergent Evolution of Multiple Mutations Improves the Viral Fitness of SARS-CoV-2 Variants by Balancing Positive and Negative Selection. Biochemistry. 2022 06 07; 61(11):963-980. PMID: 35511584.
      View in: PubMed
    3. Srivastava A, Mallela KMG, Deorkar N, Brophy G. Manufacturing Challenges and Rational Formulation Development for AAV Viral Vectors. J Pharm Sci. 2021 07; 110(7):2609-2624. PMID: 33812887.
      View in: PubMed
    4. Her C, Tanenbaum LM, Bandi S, Randolph TW, Thirumangalathu R, Mallela KMG, Carpenter JF, Elias Y. Effects of Tubing Type, Operating Parameters, and Surfactants on Particle Formation During Peristaltic Filling Pump Processing of a mAb Formulation. J Pharm Sci. 2020 04; 109(4):1439-1448. PMID: 31954724.
      View in: PubMed
    5. Bandi S, Singh SM, Shah DD, Upadhyay V, Mallela KMG. 2D NMR Analysis of the Effect of Asparagine Deamidation Versus Methionine Oxidation on the Structure, Stability, Aggregation, and Function of a Therapeutic Protein. Mol Pharm. 2019 11 04; 16(11):4621-4635. PMID: 31483994.
      View in: PubMed
    6. Shah DD, Singh SM, Mallela KMG. Effect of Chemical Oxidation on the Higher Order Structure, Stability, Aggregation, and Biological Function of Interferon Alpha-2a: Role of Local Structural Changes Detected by 2D NMR. Pharm Res. 2018 Oct 15; 35(12):232. PMID: 30324266.
      View in: PubMed
    7. Shah DD, Zhang J, Hsieh MC, Sundaram S, Maity H, Mallela KMG. Effect of Peroxide- Versus Alkoxyl-Induced Chemical Oxidation on the Structure, Stability, Aggregation, and Function of a Therapeutic Monoclonal Antibody. J Pharm Sci. 2018 11; 107(11):2789-2803. PMID: 30075161.
      View in: PubMed
    8. Shah DD, Zhang J, Maity H, Mallela KMG. Effect of photo-degradation on the structure, stability, aggregation, and function of an IgG1 monoclonal antibody. Int J Pharm. 2018 Aug 25; 547(1-2):438-449. PMID: 29883793.
      View in: PubMed
    9. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 17322530.
      View in: PubMed
    10. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 16690080.
      View in: PubMed
    11. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 15774579.
      View in: PubMed
    12. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 15657118.
      View in: PubMed
    13. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 15476824.
      View in: PubMed
    14. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 15283915.
      View in: PubMed
    15. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 22275054.
      View in: PubMed
    16. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 15877373.
      View in: PubMed
    17. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 16142911.
      View in: PubMed
    18. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 24628267.
      View in: PubMed
    19. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 24678640.
      View in: PubMed
    20. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 26288220.
      View in: PubMed
    21. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 28443334.
      View in: PubMed
    22. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 9356133.
      View in: PubMed
    23. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 11524670.
      View in: PubMed
    24. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 11352271.
      View in: PubMed
    25. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 32064376.
      View in: PubMed
    26. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 34543625.
      View in: PubMed
    27. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 35507641.
      View in: PubMed
    28. Shah DD, Singh SM, Dzieciatkowska M, Mallela KMG. Biophysical analysis of the effect of chemical modification by 4-oxononenal on the structure, stability, and function of binding immunoglobulin protein (BiP). PLoS One. 2017; 12(9):e0183975. PMID: 28886061.
      View in: PubMed
    29. Singh SM, Bandi S, Jones DNM, Mallela KMG. Effect of Polysorbate 20 and Polysorbate 80 on the Higher-Order Structure of a Monoclonal Antibody and Its Fab and Fc Fragments Probed Using 2D Nuclear Magnetic Resonance Spectroscopy. J Pharm Sci. 2017 12; 106(12):3486-3498. PMID: 28843351.
      View in: PubMed
    30. Singh SM, Bandi S, Mallela KM. The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains. Biochemistry. 2015 Nov 24; 54(46):6942-50. PMID: 26516677.
      View in: PubMed
    31. Singh SM, Bandi S, Shah DD, Armstrong G, Mallela KM. Missense mutation Lys18Asn in dystrophin that triggers X-linked dilated cardiomyopathy decreases protein stability, increases protein unfolding, and perturbs protein structure, but does not affect protein function. PLoS One. 2014; 9(10):e110439. PMID: 25340340.
      View in: PubMed
    32. Bis RL, Singh SM, Cabello-Villegas J, Mallela KM. Role of benzyl alcohol in the unfolding and aggregation of interferon a-2a. J Pharm Sci. 2015 Feb; 104(2):407-15. PMID: 25100180.
      View in: PubMed
    33. Bis RL, Mallela KM. Antimicrobial preservatives induce aggregation of interferon alpha-2a: the order in which preservatives induce protein aggregation is independent of the protein. Int J Pharm. 2014 Sep 10; 472(1-2):356-61. PMID: 24974985.
      View in: PubMed
    34. Bis RL, Stauffer TM, Singh SM, Lavoie TB, Mallela KM. High yield soluble bacterial expression and streamlined purification of recombinant human interferon a-2a. Protein Expr Purif. 2014 Jul; 99:138-46. PMID: 24794500.
      View in: PubMed
    35. Hutchings RL, Singh SM, Cabello-Villegas J, Mallela KM. Effect of antimicrobial preservatives on partial protein unfolding and aggregation. J Pharm Sci. 2013 Feb; 102(2):365-76. PMID: 23169345.
      View in: PubMed
    36. Singh SM, Mallela KM. The N-terminal actin-binding tandem calponin-homology (CH) domain of dystrophin is in a closed conformation in solution and when bound to F-actin. Biophys J. 2012 Nov 07; 103(9):1970-8. PMID: 23199925.
      View in: PubMed
    37. Singh SM, Hutchings RL, Mallela KM. Mechanisms of m-cresol-induced protein aggregation studied using a model protein cytochrome c. J Pharm Sci. 2011 May; 100(5):1679-89. PMID: 21229618.
      View in: PubMed
    38. Singh SM, Cabello-Villegas J, Hutchings RL, Mallela KM. Role of partial protein unfolding in alcohol-induced protein aggregation. Proteins. 2010 Sep; 78(12):2625-37. PMID: 20597088.
      View in: PubMed
    39. Singh SM, Kongari N, Cabello-Villegas J, Mallela KM. Missense mutations in dystrophin that trigger muscular dystrophy decrease protein stability and lead to cross-beta aggregates. Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34):15069-74. PMID: 20696926.
      View in: PubMed
    40. Bédard S, Krishna MM, Mayne L, Englander SW. Protein folding: independent unrelated pathways or predetermined pathway with optional errors. Proc Natl Acad Sci U S A. 2008 May 20; 105(20):7182-7. PMID: 18480257.
      View in: PubMed
    41. Englander SW, Mayne L, Krishna MM. Protein folding and misfolding: mechanism and principles. Q Rev Biophys. 2007 Nov; 40(4):287-326. PMID: 18405419.
      View in: PubMed
    42. Krishna MM, Maity H, Rumbley JN, Englander SW. Branching in the sequential folding pathway of cytochrome c. Protein Sci. 2007 Sep; 16(9):1946-56. PMID: 17660254.
      View in: PubMed
    43. Krishna MM, Lin Y, Mayne L, Englander SW. Intimate view of a kinetic protein folding intermediate: residue-resolved structure, interactions, stability, folding and unfolding rates, homogeneity. J Mol Biol. 2003 Nov 28; 334(3):501-13. PMID: 14623190.
      View in: PubMed
    44. Hoang L, Maity H, Krishna MM, Lin Y, Englander SW. Folding units govern the cytochrome c alkaline transition. J Mol Biol. 2003 Aug 01; 331(1):37-43. PMID: 12875834.
      View in: PubMed
    45. Krishna MM, Lin Y, Rumbley JN, Englander SW. Cooperative omega loops in cytochrome c: role in folding and function. J Mol Biol. 2003 Aug 01; 331(1):29-36. PMID: 12875833.
      View in: PubMed
    46. Hoang L, Bedard S, Krishna MM, Lin Y, Englander SW. Cytochrome c folding pathway: kinetic native-state hydrogen exchange. Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19):12173-8. PMID: 12196629.
      View in: PubMed
    47. Krishna MM, Periasamy N. Location and orientation of DODCI in lipid bilayer membranes: effects of lipid chain length and unsaturation. Biochim Biophys Acta. 1999 Nov 09; 1461(1):58-68. PMID: 10556488.
      View in: PubMed
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