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Liping Yu

TitleAssoc Professor-Research
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Barbara Davis Center
Phone303/724-6808

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gu Y, Zhao Z, Miao D, High H, Yang T, Yu L. Electrochemiluminescence Assays for Human Islet Autoantibodies. J Vis Exp. 2018 03 23; (133). PMID: 29630056.
      View in: PubMed
    2. Gu Y, Zhao Z, High H, Yang T, Yu L. Islet Autoantibody Detection by Electrochemiluminescence (ECL) Assay. J Clin Cell Immunol. 2017; 8(6). PMID: 29487479.
      View in: PubMed
    3. Abbott JK, Huoh YS, Reynolds PR, Yu L, Rewers M, Reddy M, Anderson MS, Hur S, Gelfand EW. Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE). J Autoimmun. 2018 Mar; 88:114-120. PMID: 29129473.
      View in: PubMed
    4. Yu L, Zhao Z, Steck AK. T1D Autoantibodies: room for improvement? Curr Opin Endocrinol Diabetes Obes. 2017 Aug; 24(4):285-291. PMID: 28509692.
      View in: PubMed
    5. Zhao Z, Miao D, Waugh K, Taki I, Dong F, Liu E, Rewers M, Liu Y, Yu L. Higher Sensitivity and Earlier Identification of Celiac Disease Autoimmunity by a Nonradioactive Assay for Transglutaminase Autoantibodies. J Immunol Res. 2016; 2016:2904563. PMID: 28127566.
      View in: PubMed
    6. Michels AW, Landry LG, McDaniel KA, Yu L, Campbell-Thompson M, Kwok WW, Jones KL, Gottlieb PA, Kappler JW, Tang Q, Roep BO, Atkinson MA, Mathews CE, Nakayama M. Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes. Diabetes. 2017 03; 66(3):722-734. PMID: 27920090.
      View in: PubMed
    7. Zhao Z, Yu L. High-Throughput Screening in General Population for Type 1 Diabetes. Diabetes Technol Ther. 2016 11; 18(11):674-676. PMID: 27860497.
      View in: PubMed
    8. Fouts A, Pyle L, Yu L, Miao D, Michels A, Krischer J, Sosenko J, Gottlieb P, Steck AK. Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects? Diabetes Care. 2016 10; 39(10):1738-44. PMID: 27456836; PMCID: PMC5033080 [Available on 10/01/17].
      View in: PubMed, PubMed Central
    9. Steck AK, Dong F, Waugh K, Frohnert BI, Yu L, Norris JM, Rewers MJ. Predictors of slow progression to diabetes in children with multiple islet autoantibodies. J Autoimmun. 2016 08; 72:113-7. PMID: 27255734.
      View in: PubMed
    10. Steck AK, Fouts A, Miao D, Zhao Z, Dong F, Sosenko J, Gottlieb P, Rewers MJ, Yu L. ECL-IAA and ECL-GADA Can Identify High-Risk Single Autoantibody-Positive Relatives in the TrialNet Pathway to Prevention Study. Diabetes Technol Ther. 2016 07; 18(7):410-4. PMID: 26991969; PMCID: PMC4931768 [Available on 07/01/17].
      View in: PubMed, PubMed Central
    11. Zhao Z, Miao D, Michels A, Steck A, Dong F, Rewers M, Yu L. A multiplex assay combining insulin, GAD, IA-2 and transglutaminase autoantibodies to facilitate screening for pre-type 1 diabetes and celiac disease. J Immunol Methods. 2016 Mar; 430:28-32. PMID: 26809048.
      View in: PubMed
    12. Yu L. Islet Autoantibody Detection by Electrochemiluminescence (ECL) Assay. Methods Mol Biol. 2016; 1433:85-91. PMID: 26659802.
      View in: PubMed
    13. Yu L, Raj R. On the thermodynamically stable amorphous phase of polymer-derived silicon oxycarbide. Sci Rep. 2015 Sep 30; 5:14550. PMID: 26419962; PMCID: PMC4588588.
      View in: PubMed, PubMed Central
    14. Gesualdo PD, Bautista KA, Waugh KC, Yu L, Norris JM, Rewers MJ, Baxter J. Feasibility of screening for T1D and celiac disease in a pediatric clinic setting. Pediatr Diabetes. 2016 09; 17(6):441-8. PMID: 26251221.
      View in: PubMed
    15. Shah VN, Yu L. Comment on Liu et al. Latent autoimmune diabetes in adults with low-titer GAD antibodies: similar disease progression with type 2 diabetes: a nationwide, multicenter prospective study (LADA China Study 3). Diabetes Care 2015;38:16-21. Diabetes Care. 2015 Mar; 38(3):e43. PMID: 25715424.
      View in: PubMed
    16. Miao D, Steck AK, Zhang L, Guyer KM, Jiang L, Armstrong T, Muller SM, Krischer J, Rewers M, Yu L. Electrochemiluminescence assays for insulin and glutamic acid decarboxylase autoantibodies improve prediction of type 1 diabetes risk. Diabetes Technol Ther. 2015 Feb; 17(2):119-27. PMID: 25562486; PMCID: PMC4321773.
      View in: PubMed, PubMed Central
    17. Yu L, Zunger A. A polarity-induced defect mechanism for conductivity and magnetism at polar-nonpolar oxide interfaces. Nat Commun. 2014 Oct 13; 5:5118. PMID: 25307265.
      View in: PubMed
    18. Liu E, McDaniel K, Case S, Yu L, Gerhartz B, Ostermann N, Fankhauser G, Hungerford V, Zou C, Luyten M, Seidl KJ, Michels AW. Exploring T cell reactivity to gliadin in young children with newly diagnosed celiac disease. Autoimmune Dis. 2014; 2014:927190. PMID: 24724018; PMCID: PMC3958769.
      View in: PubMed, PubMed Central
    19. Miao D, Guyer KM, Dong F, Jiang L, Steck AK, Rewers M, Eisenbarth GS, Yu L. GAD65 autoantibodies detected by electrochemiluminescence assay identify high risk for type 1 diabetes. Diabetes. 2013 Dec; 62(12):4174-8. PMID: 23974918; PMCID: PMC3837058.
      View in: PubMed, PubMed Central
    20. Yu L, Dong F, Miao D, Fouts AR, Wenzlau JM, Steck AK. Proinsulin/Insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity. Diabetes Care. 2013 Aug; 36(8):2266-70. PMID: 23423694.
      View in: PubMed
    21. Baker PR, Nanduri P, Gottlieb PA, Yu L, Klingensmith GJ, Eisenbarth GS, Barker JM. Predicting the onset of Addison's disease: ACTH, renin, cortisol and 21-hydroxylase autoantibodies. Clin Endocrinol (Oxf). 2012 May; 76(5):617-24. PMID: 22066755; PMCID: PMC4963152.
      View in: PubMed, PubMed Central
    22. Yu L, Boulware DC, Beam CA, Hutton JC, Wenzlau JM, Greenbaum CJ, Bingley PJ, Krischer JP, Sosenko JM, Skyler JS, Eisenbarth GS, Mahon JL. Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. Diabetes Care. 2012 Jun; 35(6):1213-8. PMID: 22446173.
      View in: PubMed
    23. Yu L, Miao D, Scrimgeour L, Johnson K, Rewers M, Eisenbarth GS. Distinguishing persistent insulin autoantibodies with differential risk: nonradioactive bivalent proinsulin/insulin autoantibody assay. Diabetes. 2012 Jan; 61(1):179-86. PMID: 22124462; PMCID: PMC3237666.
      View in: PubMed, PubMed Central
    24. Yu L, Herold K, Krause-Steinrauf H, McGee PL, Bundy B, Pugliese A, Krischer J, Eisenbarth GS. Rituximab selectively suppresses specific islet antibodies. Diabetes. 2011 Oct; 60(10):2560-5. PMID: 21831969; PMCID: PMC3178300.
      View in: PubMed, PubMed Central
    25. Steck AK, Johnson K, Barriga KJ, Miao D, Yu L, Hutton JC, Eisenbarth GS, Rewers MJ. Age of islet autoantibody appearance and mean levels of insulin, but not GAD or IA-2 autoantibodies, predict age of diagnosis of type 1 diabetes: diabetes autoimmunity study in the young. Diabetes Care. 2011 Jun; 34(6):1397-9. PMID: 21562325; PMCID: PMC3114355.
      View in: PubMed, PubMed Central
    26. Dang M, Rockell J, Wagner R, Wenzlau JM, Yu L, Hutton JC, Gottlieb PA, Davidson HW. Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8. J Immunol. 2011 May 15; 186(10):6056-63. PMID: 21471440; PMCID: PMC3088514.
      View in: PubMed, PubMed Central
    27. Yu L, Liu Y, Miao D, Wenzlau J, Davidson H, Hutton J, Eisenbarth GS. Triple chimeric islet autoantigen IA2-ZnT8WR to facilitate islet autoantibody determination. J Immunol Methods. 2010 Feb 28; 353(1-2):20-3. PMID: 20035758.
      View in: PubMed
    28. Triolo TM, Baschal EE, Armstrong TK, Toews CS, Fain PR, Rewers MJ, Yu L, Miao D, Eisenbarth GS, Gottlieb PA, Barker JM. Homozygosity of the polymorphism MICA5.1 identifies extreme risk of progression to overt adrenal insufficiency among 21-hydroxylase antibody-positive patients with type 1 diabetes. J Clin Endocrinol Metab. 2009 Nov; 94(11):4517-23. PMID: 19820007; PMCID: PMC2775653.
      View in: PubMed, PubMed Central
    29. Li M, Yu L, Tiberti C, Bonamico M, Taki I, Miao D, Murray JA, Rewers MJ, Hoffenberg EJ, Agardh D, Mueller P, Stern M, Bonifacio E, Liu E. A report on the International Transglutaminase Autoantibody Workshop for Celiac Disease. Am J Gastroenterol. 2009 Jan; 104(1):154-63. PMID: 19098864; PMCID: PMC2904747.
      View in: PubMed, PubMed Central
    30. Wenzlau JM, Moua O, Sarkar SA, Yu L, Rewers M, Eisenbarth GS, Davidson HW, Hutton JC. SlC30A8 is a major target of humoral autoimmunity in type 1 diabetes and a predictive marker in prediabetes. Ann N Y Acad Sci. 2008 Dec; 1150:256-9. PMID: 19120307.
      View in: PubMed
    31. Wenzlau JM, Liu Y, Yu L, Moua O, Fowler KT, Rangasamy S, Walters J, Eisenbarth GS, Davidson HW, Hutton JC. A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes. Diabetes. 2008 Oct; 57(10):2693-7. PMID: 18591387; PMCID: PMC2551679.
      View in: PubMed, PubMed Central
    32. Zhang L, Gianani R, Nakayama M, Liu E, Kobayashi M, Baschal E, Yu L, Babu S, Dawson A, Johnson K, Jahromi M, Aly T, Fain P, Barker J, Rewers M, Eisenbarth GS. Type 1 diabetes: chronic progressive autoimmune disease. Novartis Found Symp. 2008; 292:85-94; discussion 94-8, 122-9, 202-3. PMID: 19203094.
      View in: PubMed
    33. Wenzlau JM, Juhl K, Yu L, Moua O, Sarkar SA, Gottlieb P, Rewers M, Eisenbarth GS, Jensen J, Davidson HW, Hutton JC. The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):17040-5. PMID: 17942684; PMCID: PMC2040407.
      View in: PubMed, PubMed Central
    34. Yu L, Wang J, O'Dell JR, Oates J, Arend WP, Eisenbarth GS. Anti-dsDNA antibody assay: high specificity and sensitivity with a filtration radioassay in comparison to low specificity with the standard ELISA. J Rheumatol. 2007 Apr; 34(4):734-9. PMID: 17407230.
      View in: PubMed
    35. Aly TA, Ide A, Humphrey K, Barker JM, Steck A, Erlich HA, Yu L, Miao D, Redondo MJ, McFann K, Roberts CM, Babu SR, Norris JM, Eisenbarth GS, Rewers MJ. Genetic prediction of autoimmunity: initial oligogenic prediction of anti-islet autoimmunity amongst DR3/DR4-DQ8 relatives of patients with type 1A diabetes. J Autoimmun. 2005; 25 Suppl:40-5. PMID: 16242305.
      View in: PubMed
    36. Nakayama M, Abiru N, Moriyama H, Babaya N, Liu E, Miao D, Yu L, Wegmann DR, Hutton JC, Elliott JF, Eisenbarth GS. Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature. 2005 May 12; 435(7039):220-3. PMID: 15889095; PMCID: PMC1364531.
      View in: PubMed, PubMed Central
    37. Barker JM, Yu J, Yu L, Wang J, Miao D, Bao F, Hoffenberg E, Nelson JC, Gottlieb PA, Rewers M, Eisenbarth GS. Autoantibody "subspecificity" in type 1 diabetes: risk for organ-specific autoimmunity clusters in distinct groups. Diabetes Care. 2005 Apr; 28(4):850-5. PMID: 15793184.
      View in: PubMed
    38. Devendra D, Paronen J, Liu E, Moriyama H, Miao D, Yu L, Eisenbarth GS. Differential immune induction with subcutaneous versus oral administration of a diabetogenic insulin peptide in the NOD mouse. Ann N Y Acad Sci. 2004 Dec; 1029:328-30. PMID: 15681772.
      View in: PubMed
    39. Devendra D, Paronen J, Liu E, Moriyama H, Taylor R, Miao D, Yu L, Eisenbarth G. Comparative study of oral versus subcutaneous B:9-23 insulin peptide in Balb/c mice as an experimental model for autoimmune diabetes. Ann N Y Acad Sci. 2004 Dec; 1029:331-3. PMID: 15681773.
      View in: PubMed
    40. Redondo MJ, Fain PR, Krischer JP, Yu L, Cuthbertson D, Winter WE, Eisenbarth GS. Expression of beta-cell autoimmunity does not differ between potential dizygotic twins and siblings of patients with type 1 diabetes. J Autoimmun. 2004 Nov; 23(3):275-9. PMID: 15501398.
      View in: PubMed
    41. Barker JM, Ide A, Hostetler C, Yu L, Miao D, Fain PR, Eisenbarth GS, Gottlieb PA. Endocrine and immunogenetic testing in individuals with type 1 diabetes and 21-hydroxylase autoantibodies: Addison's disease in a high-risk population. J Clin Endocrinol Metab. 2005 Jan; 90(1):128-34. PMID: 15483092.
      View in: PubMed
    42. Barker JM, Barriga KJ, Yu L, Miao D, Erlich HA, Norris JM, Eisenbarth GS, Rewers M. Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). J Clin Endocrinol Metab. 2004 Aug; 89(8):3896-902. PMID: 15292324.
      View in: PubMed
    43. Paronen J, Liu E, Moriyama H, Devendra D, Ide A, Taylor R, Yu L, Miao D, Melanitou E, Eisenbarth GS. Genetic differentiation of poly I:C from B:9-23 peptide induced experimental autoimmune diabetes. J Autoimmun. 2004 Jun; 22(4):307-13. PMID: 15120754.
      View in: PubMed
    44. Aly T, Devendra D, Barker J, Liu E, Yu L, Eisenbarth GS. Heterophile antibodies masquerade as interferon-alpha in subjects with new-onset type 1 diabetes. Diabetes Care. 2004 May; 27(5):1205-6. PMID: 15111547.
      View in: PubMed
    45. Devendra D, Yu L, Eisenbarth GS. Endocrine autoantibodies. Clin Lab Med. 2004 Mar; 24(1):275-303. PMID: 15157566.
      View in: PubMed
    46. Stanley HM, Norris JM, Barriga K, Hoffman M, Yu L, Miao D, Erlich HA, Eisenbarth GS, Rewers M. Is presence of islet autoantibodies at birth associated with development of persistent islet autoimmunity? The Diabetes Autoimmunity Study in the Young (DAISY). Diabetes Care. 2004 Feb; 27(2):497-502. PMID: 14747235.
      View in: PubMed
    47. Yu L, Eisenbarth GS. Humoral autoimmunity. Adv Exp Med Biol. 2004; 552:247-67. PMID: 15622967.
      View in: PubMed
    48. Liu E, Yu L, Moriyama H, Eisenbarth GS. Animal models of insulin-dependent diabetes. Methods Mol Med. 2004; 102:195-212. PMID: 15286387.
      View in: PubMed
    49. Yu L, Eisenbarth G, Bonifacio E, Thomas J, Atkinson M, Wasserfall C. The second murine autoantibody workshop: remarkable interlaboratory concordance for radiobinding assays to identify insulin autoantibodies in nonobese diabetic mice. Ann N Y Acad Sci. 2003 Nov; 1005:1-12. PMID: 14679035.
      View in: PubMed
    50. Melanitou E, Liu E, Miao D, Yu L, Glimcher LH, Eisenbarth G. Absence of the T-bet gene coding for the Th1-related transcription factor does not affect diabetes-associated phenotypes in Balb/c mice. Ann N Y Acad Sci. 2003 Nov; 1005:187-91. PMID: 14679057.
      View in: PubMed
    51. Liu E, Moriyama H, Paronen J, Abiru N, Miao D, Yu L, Taylor RM, Eisenbarth GS. Nondepleting anti-CD4 monoclonal antibody prevents diabetes and blocks induction of insulin autoantibodies following insulin peptide B:9-23 immunization in the NOD mouse. J Autoimmun. 2003 Nov; 21(3):213-9. PMID: 14599846.
      View in: PubMed
    52. Liu E, Moriyama H, Abiru N, Miao D, Yu L, Taylor RM, Finkelman FD, Eisenbarth GS. Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23. J Clin Invest. 2002 Oct; 110(7):1021-7. PMID: 12370280; PMCID: PMC151146.
      View in: PubMed, PubMed Central
    53. Eisenbarth GS, Moriyama H, Robles DT, Liu E, Yu L, Babu S, Redondo MJ, Redondo M, Gottlieb P, Wegmann D, Rewers M. Insulin autoimmunity: prediction/precipitation/prevention type 1A diabetes. Autoimmun Rev. 2002 May; 1(3):139-45. PMID: 12849007.
      View in: PubMed
    54. Moriyama H, Wen L, Abiru N, Liu E, Yu L, Miao D, Gianani R, Wong FS, Eisenbarth GS. Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide. Proc Natl Acad Sci U S A. 2002 Apr 16; 99(8):5539-44. PMID: 11943868; PMCID: PMC122805.
      View in: PubMed, PubMed Central
    55. Yu L, Cuthbertson DD, Eisenbarth GS, Krischer JP. Diabetes Prevention Trial 1: prevalence of GAD and ICA512 (IA-2) autoantibodies by relationship to proband. Ann N Y Acad Sci. 2002 Apr; 958:254-8. PMID: 12021118.
      View in: PubMed
    56. Robles DT, Eisenbarth GS, Wang T, Erlich HA, Bugawan TL, Babu SR, Barriga K, Norris JM, Hoffman M, Klingensmith G, Yu L, Rewers M. Millennium award recipient contribution. Identification of children with early onset and high incidence of anti-islet autoantibodies. Clin Immunol. 2002 Mar; 102(3):217-24. PMID: 11890708.
      View in: PubMed
    57. Miao D, Yu L, Tiberti C, Cuthbertson DD, Rewers M, di Mario U, Eisenbarth GS, Dotta F. ICA512(IA-2) epitope specific assays distinguish transient from diabetes associated autoantibodies. J Autoimmun. 2002 Mar; 18(2):191-6. PMID: 11908951.
      View in: PubMed
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