 Nicotinic Antagonists
"Nicotinic Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
| Descriptor ID |
D018733
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| MeSH Number(s) |
D27.505.519.625.120.200.700 D27.505.696.577.120.200.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nicotinic Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Nicotinic Antagonists".
This graph shows the total number of publications written about "Nicotinic Antagonists" by people in this website by year, and whether "Nicotinic Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 1 | 2 | | 2010 | 0 | 2 | 2 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 2 | 3 | | 2013 | 0 | 2 | 2 | | 2017 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nicotinic Antagonists" by people in Profiles.
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Williams BM, Steed ND, Woolley JT, Moedl AA, Nelson CA, Jones GC, Burris MD, Arias HR, Kim OH, Jang EY, Hone AJ, McIntosh JM, Yorgason JT, Steffensen SC. Catharanthine Modulates Mesolimbic Dopamine Transmission and Nicotine Psychomotor Effects via Inhibition of a6-Nicotinic Receptors and Dopamine Transporters. ACS Chem Neurosci. 2024 05 01; 15(9):1738-1754.
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Rahman MM, Teng J, Worrell BT, Noviello CM, Lee M, Karlin A, Stowell MHB, Hibbs RE. Structure of the Native Muscle-type Nicotinic Receptor and Inhibition by Snake Venom Toxins. Neuron. 2020 06 17; 106(6):952-962.e5.
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Bai X, Stitzel JA, Bai A, Zambrano CA, Phillips M, Marrack P, Chan ED. Nicotine Impairs Macrophage Control of Mycobacterium tuberculosis. Am J Respir Cell Mol Biol. 2017 09; 57(3):324-333.
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Hall BJ, Abreu-Villa?a Y, Cauley M, Junaid S, White H, Kiany A, Levin ED. The ventral hippocampal muscarinic cholinergic system plays a key role in sexual dimorphisms of spatial working memory in rats. Neuropharmacology. 2017 05 01; 117:106-113.
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Ghasemi M, Hadipour-Niktarash A. Pathologic role of neuronal nicotinic acetylcholine receptors in epileptic disorders: implication for pharmacological interventions. Rev Neurosci. 2015; 26(2):199-223.
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Wang Y, Lee JW, Oh G, Grady SR, McIntosh JM, Brunzell DH, Cannon JR, Drenan RM. Enhanced synthesis and release of dopamine in transgenic mice with gain-of-function a6* nAChRs. J Neurochem. 2014 Apr; 129(2):315-27.
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Soll LG, Grady SR, Salminen O, Marks MJ, Tapper AR. A role for a4(non-a6)* nicotinic acetylcholine receptors in motor behavior. Neuropharmacology. 2013 Oct; 73:19-30.
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Tammim?ki A, Herder P, Li P, Esch C, Laughlin JR, Akk G, Stitzel JA. Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by a3?4a5 nicotinic acetylcholine receptors. Neuropharmacology. 2012 Nov; 63(6):1002-11.
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McClure-Begley TD, Wageman CR, Grady SR, Marks MJ, McIntosh JM, Collins AC, Whiteaker P. A novel a-conotoxin MII-sensitive nicotinic acetylcholine receptor modulates [(3) H]-GABA release in the superficial layers of the mouse superior colliculus. J Neurochem. 2012 Jul; 122(1):48-57.
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Ortiz NC, O'Neill HC, Marks MJ, Grady SR. Varenicline blocks ?2*-nAChR-mediated response and activates ?4*-nAChR-mediated responses in mice in vivo. Nicotine Tob Res. 2012 Jun; 14(6):711-9.
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