 Oligonucleotides
"Oligonucleotides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed)
| Descriptor ID |
D009841
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| MeSH Number(s) |
D13.695.578.424
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oligonucleotides".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotides".
This graph shows the total number of publications written about "Oligonucleotides" by people in this website by year, and whether "Oligonucleotides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 1 | 3 | | 1994 | 0 | 1 | 1 | | 1995 | 2 | 2 | 4 | | 1996 | 1 | 1 | 2 | | 1997 | 1 | 1 | 2 | | 1998 | 1 | 2 | 3 | | 1999 | 2 | 2 | 4 | | 2000 | 3 | 1 | 4 | | 2001 | 1 | 2 | 3 | | 2002 | 1 | 3 | 4 | | 2003 | 4 | 1 | 5 | | 2004 | 1 | 5 | 6 | | 2005 | 0 | 5 | 5 | | 2006 | 0 | 4 | 4 | | 2007 | 1 | 3 | 4 | | 2008 | 3 | 3 | 6 | | 2009 | 2 | 1 | 3 | | 2010 | 2 | 4 | 6 | | 2011 | 1 | 3 | 4 | | 2012 | 1 | 2 | 3 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 3 | 4 | | 2015 | 4 | 2 | 6 | | 2016 | 0 | 2 | 2 | | 2017 | 4 | 0 | 4 | | 2018 | 5 | 0 | 5 | | 2019 | 3 | 0 | 3 | | 2020 | 6 | 1 | 7 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oligonucleotides" by people in Profiles.
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Le BT, Paul S, Jastrzebska K, Langer H, Caruthers MH, Veedu RN. Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2207956119.
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Kumar P, Caruthers MH. DNA Analogues Modified at the Nonlinking Positions of Phosphorus. Acc Chem Res. 2020 10 20; 53(10):2152-2166.
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Han X, Fairbanks BD, Sinha J, Bowman CN. Sequence-Controlled Synthesis of Advanced Clickable Synthetic Oligonucleotides. Macromol Rapid Commun. 2020 Aug; 41(16):e2000327.
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Moshe-Lilie O, Visser A, Chahin N, Ragole T, Dimitrova D, Karam C. Nusinersen in adult patients with spinal muscular atrophy: Observations from a single center. Neurology. 2020 07 28; 95(4):e413-e416.
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Lowey B, Whiteley AT, Keszei AFA, Morehouse BR, Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P, Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY, Kranzusch PJ. CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection. Cell. 2020 07 09; 182(1):38-49.e17.
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Weaver JJ, Hallam DK, Chick JFB, Vaidya S, Shin DS, Natarajan N, Rad N, Reis J, Koo KSH, Shivaram GM, Thibodeau A, Apkon S, Monroe EJ. Transforaminal intrathecal delivery of nusinersen for older children and adults with spinal muscular atrophy and complex spinal anatomy: an analysis of 200 consecutive injections. J Neurointerv Surg. 2021 Jan; 13(1):75-78.
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Feldman AG, Parsons JA, Dutmer CM, Veerapandiyan A, Hafberg E, Maloney N, Mack CL. Subacute Liver Failure Following Gene Replacement Therapy for Spinal Muscular Atrophy Type 1. J Pediatr. 2020 10; 225:252-258.e1.
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Harguindey A, Culver HR, Sinha J, Bowman CN, Cha JN. Efficient cellular uptake of click nucleic acid modified proteins. Chem Commun (Camb). 2020 May 02; 56(35):4820-4823.
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Krishna H, Jastrzebska K, Caruthers M. Exploring site-specific activation of bis-N,N'-dialkylaminophosphordiamidites and the synthesis of morpholinophosphoramidate oligonucleotides. FEBS Lett. 2019 07; 593(13):1459-1467.
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Traeger JC, Lamberty Z, Schwartz DK. Influence of Oligonucleotide Grafting Density on Surface-Mediated DNA Transport and Hybridization. ACS Nano. 2019 07 23; 13(7):7850-7859.
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