 Acetaminophen
"Acetaminophen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
| Descriptor ID |
D000082
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| MeSH Number(s) |
D02.065.199.092.040 D02.092.146.113.092.040
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| Concept/Terms |
Acetaminophen- Acetaminophen
- Acetominophen
- Hydroxyacetanilide
- APAP
- p-Acetamidophenol
- p-Hydroxyacetanilide
- Paracetamol
- N-(4-Hydroxyphenyl)acetanilide
- Acetamidophenol
- N-Acetyl-p-aminophenol
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Below are MeSH descriptors whose meaning is more general than "Acetaminophen".
Below are MeSH descriptors whose meaning is more specific than "Acetaminophen".
This graph shows the total number of publications written about "Acetaminophen" by people in this website by year, and whether "Acetaminophen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1994 | 0 | 2 | 2 | | 1995 | 1 | 1 | 2 | | 1996 | 2 | 0 | 2 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 3 | 5 | | 2004 | 3 | 0 | 3 | | 2005 | 3 | 0 | 3 | | 2006 | 1 | 1 | 2 | | 2007 | 6 | 1 | 7 | | 2008 | 2 | 2 | 4 | | 2009 | 3 | 1 | 4 | | 2010 | 9 | 0 | 9 | | 2011 | 8 | 1 | 9 | | 2012 | 6 | 1 | 7 | | 2013 | 3 | 2 | 5 | | 2014 | 6 | 0 | 6 | | 2015 | 3 | 0 | 3 | | 2016 | 7 | 0 | 7 | | 2017 | 6 | 3 | 9 | | 2018 | 8 | 4 | 12 | | 2019 | 8 | 0 | 8 | | 2020 | 4 | 2 | 6 | | 2021 | 12 | 5 | 17 | | 2022 | 5 | 0 | 5 |
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Below are the most recent publications written about "Acetaminophen" by people in Profiles.
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Arnold CG, Dylla L, Monte AA, Heard K, Heard S, D'Alessandro A, Reynolds K, Dart R, Rumack B, Sonn B. Metabolomic Evaluation of N-Acetyl-p-Benzoquinone Imine Protein Adduct Formation with Therapeutic Acetaminophen Administration: Sex-based Physiologic Differences. J Med Toxicol. 2022 Oct; 18(4):297-310.
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McCulley DJ, Jensen EA, Sucre JMS, McKenna S, Sherlock LG, Dobrinskikh E, Wright CJ. Racing against time: leveraging preclinical models to understand pulmonary susceptibility to perinatal acetaminophen exposures. Am J Physiol Lung Cell Mol Physiol. 2022 07 01; 323(1):L1-L13.
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Wright CJ, Jensen EA. EBNEO Commentary: Paracetamol/acetaminophen to avoid PDA ligation: How to interpret impact on 18- to 24-month outcomes. Acta Paediatr. 2022 04; 111(4):901-902.
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Sherlock LG, Balasubramaniyan D, Zheng L, Grayck M, McCarthy WC, De Dios RC, Zarate MA, Orlicky DJ, De Dios R, Wright CJ. APAP-Induced I?Bß/NF?B Signaling Drives Hepatic Il6 Expression and Associated Sinusoidal Dilation. Toxicol Sci. 2022 01 24; 185(2):158-169.
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Akakpo JY, Ramachandran A, Curry SC, Rumack BH, Jaeschke H. Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose. Arch Toxicol. 2022 02; 96(2):453-465.
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Link SL, Rampon G, Osmon S, Scalzo AJ, Rumack BH. Reply to Comments on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series. Clin Toxicol (Phila). 2022 05; 60(5):668-669.
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Mudan A, Lebin JA, Wu AHB, Livshits Z. Serum iron concentrations in non-iron induced acute liver injury. Clin Chim Acta. 2022 Jan 15; 525:12-14.
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Lebin JA, Mudan A. Comment on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series. Clin Toxicol (Phila). 2022 05; 60(5):665.
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Pourbagher-Shahri AM, Schimmel J, Shirazi FM, Nakhaee S, Mehrpour O. Use of fomepizole (4-methylpyrazole) for acetaminophen poisoning: A scoping review. Toxicol Lett. 2022 Feb 01; 355:47-61.
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Mehrpour O, Saeedi F, Hadianfar A, Mégarbane B, Hoyte C. Prognostic factors of acetaminophen exposure in the United States: An analysis of 39,000 patients. Hum Exp Toxicol. 2021 Dec; 40(12_suppl):S814-S825.
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