 Acetaminophen
"Acetaminophen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
| Descriptor ID |
D000082
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| MeSH Number(s) |
D02.065.199.092.040 D02.092.146.113.092.040
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| Concept/Terms |
Acetaminophen- Acetaminophen
- Acetominophen
- Hydroxyacetanilide
- APAP
- p-Acetamidophenol
- p-Hydroxyacetanilide
- Paracetamol
- N-(4-Hydroxyphenyl)acetanilide
- Acetamidophenol
- N-Acetyl-p-aminophenol
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Below are MeSH descriptors whose meaning is more general than "Acetaminophen".
Below are MeSH descriptors whose meaning is more specific than "Acetaminophen".
This graph shows the total number of publications written about "Acetaminophen" by people in this website by year, and whether "Acetaminophen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 0 | 2 | 2 | | 1995 | 1 | 1 | 2 | | 1996 | 2 | 0 | 2 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 3 | 5 | | 2004 | 3 | 0 | 3 | | 2005 | 3 | 0 | 3 | | 2006 | 2 | 1 | 3 | | 2007 | 6 | 0 | 6 | | 2008 | 2 | 2 | 4 | | 2009 | 3 | 1 | 4 | | 2010 | 10 | 0 | 10 | | 2011 | 8 | 1 | 9 | | 2012 | 6 | 1 | 7 | | 2013 | 4 | 2 | 6 | | 2014 | 5 | 0 | 5 | | 2015 | 3 | 0 | 3 | | 2016 | 6 | 1 | 7 | | 2017 | 3 | 3 | 6 | | 2018 | 5 | 3 | 8 | | 2019 | 7 | 0 | 7 | | 2020 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Acetaminophen" by people in Profiles.
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Akakpo JY, Ramachandran A, Orhan H, Curry SC, Rumack BH, Jaeschke H. 4-methylpyrazole protects against acetaminophen-induced acute kidney injury. Toxicol Appl Pharmacol. 2020 12 15; 409:115317.
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Buckles TC, Ziemba BP, Djukovic D, Falke JJ. Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating. PLoS One. 2020; 15(5):e0233012.
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Mutsaers A, Sivilotti MLA, Yarema MC, Green JP, Johnson DW, Rumack BH. Letter in response to the Letter to the Editor by Harmouche. Clin Toxicol (Phila). 2020 03; 58(3):221-222.
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Sandoval J, Orlicky DJ, Allawzi A, Butler B, Ju C, Phan CT, Toston R, De Dios R, Nguyen L, McKenna S, Nozik-Grayck E, Wright CJ. Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung. Oxid Med Cell Longev. 2019; 2019:7595126.
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KhabazianZadeh F, Kazemi T, Nakhaee S, Ng PC, Mehrpour O. Acetaminophen poisoning-induced heart injury: a case-based review. Daru. 2019 Dec; 27(2):839-851.
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Akakpo JY, Ramachandran A, Duan L, Schaich MA, Jaeschke MW, Freudenthal BD, Ding WX, Rumack BH, Jaeschke H. Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase. Toxicol Sci. 2019 07 01; 170(1):57-68.
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Kaminsky O, Fortier MA, Jenkins BN, Stevenson RS, Gold JI, Zuk J, Golianu B, Kaplan SH, Kain ZN. Children and their parents' assessment of postoperative surgical pain: Agree or disagree? Int J Pediatr Otorhinolaryngol. 2019 Aug; 123:84-92.
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Hoyte C, Dart RC. Transition to two-bag intravenous acetylcysteine for acetaminophen overdose: a poison center's experience. Clin Toxicol (Phila). 2019 03; 57(3):217-218.
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Mutsaers A, Green JP, Sivilotti MLA, Yarema MC, Tucker D, Johnson DW, Spyker DA, Rumack BH. Changing nomogram risk zone classification with serial testing after acute acetaminophen overdose: a retrospective database analysis. Clin Toxicol (Phila). 2019 06; 57(6):380-386.
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Stremming JE, Wright CJ, Brown LD. Is paracetamol as effective as indomethacin or ibuprofen in closing a hemodynamically significant patent ductus arteriosus in preterm infants? Acta Paediatr. 2018 10; 107(10):1836.
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