 Acetaminophen
"Acetaminophen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
| Descriptor ID |
D000082
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| MeSH Number(s) |
D02.065.199.092.040 D02.092.146.113.092.040
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| Concept/Terms |
Acetaminophen- Acetaminophen
- Acetominophen
- Hydroxyacetanilide
- APAP
- p-Acetamidophenol
- p-Hydroxyacetanilide
- Paracetamol
- N-(4-Hydroxyphenyl)acetanilide
- Acetamidophenol
- N-Acetyl-p-aminophenol
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Below are MeSH descriptors whose meaning is more general than "Acetaminophen".
Below are MeSH descriptors whose meaning is more specific than "Acetaminophen".
This graph shows the total number of publications written about "Acetaminophen" by people in this website by year, and whether "Acetaminophen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 0 | 2 | 2 | | 1995 | 1 | 1 | 2 | | 1996 | 2 | 0 | 2 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 3 | 5 | | 2004 | 3 | 0 | 3 | | 2005 | 3 | 0 | 3 | | 2006 | 2 | 1 | 3 | | 2007 | 6 | 1 | 7 | | 2008 | 2 | 2 | 4 | | 2009 | 4 | 1 | 5 | | 2010 | 8 | 0 | 8 | | 2011 | 8 | 1 | 9 | | 2012 | 6 | 1 | 7 | | 2013 | 4 | 2 | 6 | | 2014 | 5 | 0 | 5 | | 2015 | 3 | 0 | 3 | | 2016 | 6 | 1 | 7 | | 2017 | 3 | 3 | 6 | | 2018 | 5 | 3 | 8 | | 2019 | 7 | 0 | 7 | | 2020 | 3 | 1 | 4 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetaminophen" by people in Profiles.
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Dobrinskikh E, Sherlock LG, Orlicky DJ, Zheng L, De Dios R, Balasubramaniyan D, Sizemore T, Butler B, Wright CJ. The developing murine lung is susceptible to acetaminophen toxicity. Am J Physiol Lung Cell Mol Physiol. 2021 05 01; 320(5):L969-L978.
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Akakpo JY, Ramachandran A, Orhan H, Curry SC, Rumack BH, Jaeschke H. 4-methylpyrazole protects against acetaminophen-induced acute kidney injury. Toxicol Appl Pharmacol. 2020 12 15; 409:115317.
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Buckles TC, Ziemba BP, Djukovic D, Falke JJ. Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating. PLoS One. 2020; 15(5):e0233012.
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Gao RY, Wang M, Liu Q, Feng D, Wen Y, Xia Y, Colgan SP, Eltzschig HK, Ju C. Hypoxia-Inducible Factor-2a Reprograms Liver Macrophages to Protect Against Acute Liver Injury Through the Production of Interleukin-6. Hepatology. 2020 06; 71(6):2105-2117.
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Wong A, Heard K, Graudins A, Dart R, Sivilotti MLA. Adducts Post Acetaminophen Overdose Treated with a 12-Hour vs 20-Hour Acetylcysteine Infusion. J Med Toxicol. 2020 04; 16(2):188-194.
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Mutsaers A, Sivilotti MLA, Yarema MC, Green JP, Johnson DW, Rumack BH. Letter in response to the Letter to the Editor by Harmouche. Clin Toxicol (Phila). 2020 03; 58(3):221-222.
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Sandoval J, Orlicky DJ, Allawzi A, Butler B, Ju C, Phan CT, Toston R, De Dios R, Nguyen L, McKenna S, Nozik-Grayck E, Wright CJ. Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung. Oxid Med Cell Longev. 2019; 2019:7595126.
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Kang AM, Padilla-Jones A, Fisher ES, Akakpo JY, Jaeschke H, Rumack BH, Gerkin RD, Curry SC. The Effect of 4-Methylpyrazole on Oxidative Metabolism of Acetaminophen in Human Volunteers. J Med Toxicol. 2020 04; 16(2):169-176.
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KhabazianZadeh F, Kazemi T, Nakhaee S, Ng PC, Mehrpour O. Acetaminophen poisoning-induced heart injury: a case-based review. Daru. 2019 Dec; 27(2):839-851.
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Akakpo JY, Ramachandran A, Duan L, Schaich MA, Jaeschke MW, Freudenthal BD, Ding WX, Rumack BH, Jaeschke H. Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase. Toxicol Sci. 2019 07 01; 170(1):57-68.
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