 Antidotes
"Antidotes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents counteracting or neutralizing the action of POISONS.
| Descriptor ID |
D000931
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| MeSH Number(s) |
D27.505.696.706.037 D27.720.799.037
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Antidotes".
Below are MeSH descriptors whose meaning is more specific than "Antidotes".
This graph shows the total number of publications written about "Antidotes" by people in this website by year, and whether "Antidotes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 1 | 1 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2004 | 1 | 1 | 2 | | 2009 | 2 | 2 | 4 | | 2010 | 2 | 1 | 3 | | 2011 | 0 | 1 | 1 | | 2012 | 5 | 0 | 5 | | 2013 | 1 | 0 | 1 | | 2014 | 6 | 1 | 7 | | 2015 | 5 | 1 | 6 | | 2016 | 7 | 1 | 8 | | 2017 | 4 | 1 | 5 | | 2018 | 6 | 1 | 7 | | 2019 | 4 | 1 | 5 | | 2020 | 4 | 0 | 4 | | 2021 | 6 | 3 | 9 | | 2022 | 2 | 1 | 3 | | 2023 | 0 | 3 | 3 | | 2024 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Antidotes" by people in Profiles.
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Bateman DN, Dart RC, Dear JW, Prescott LF, Rumack BH. Fifty years of paracetamol (acetaminophen) poisoning: the development of risk assessment and treatment 1973-2023 with particular focus on contributions published from Edinburgh and Denver. Clin Toxicol (Phila). 2023 Dec; 61(12):1020-1031.
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Nick HJ, Johnson CA, Stewart AR, Christeson SE, Bloomquist LA, Appel AS, Donkor AB, Veress LA, Logue BA, Bratcher PE, White CW. Mesna Improves Outcomes of Sulfur Mustard Inhalation Toxicity in an Acute Rat Model. J Pharmacol Exp Ther. 2024 01 17; 388(2):576-585.
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Akakpo JY, Ramachandran A, Rumack BH, Wallace DP, Jaeschke H. Lack of mitochondrial Cyp2E1 drives acetaminophen-induced ER stress-mediated apoptosis in mouse and human kidneys: Inhibition by 4-methylpyrazole but not N-acetylcysteine. Toxicology. 2023 12; 500:153692.
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Amaducci AM, Campleman SL, Li S, Karshenas DL, Spyres MB, Farrugia LA, Kang AM, Culbreth RE, Wax PM, Brent J, Aldy K. The Toxicology Investigators Consortium 2022 Annual Report. J Med Toxicol. 2023 10; 19(4):313-340.
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Bebarta VS, Shi X, Zheng S, Hendry-Hofer TB, Severance CC, Behymer MM, Boss GR, Mahon S, Brenner M, Knipp GT, Davisson VJ, Peterson RT, MacRae CA, Rutter J, Gerszten RE, Nath AK. Intramuscular administration of glyoxylate rescues swine from lethal cyanide poisoning and ameliorates the biochemical sequalae of cyanide intoxication. Toxicol Sci. 2023 01 31; 191(1):90-105.
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Bhadra S, Chan A, Hendry-Hofer TB, Boss GR, Bebarta VS, Logue BA. Analysis of bisaminotetrazole cobinamide, a next-generation antidote for cyanide, hydrogen sulfide and methanethiol poisoning, in swine plasma by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Oct 01; 1208:123392.
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Sudanagunta S, Camarena-Michel A, Pennington S, Leonard J, Hoyte C, Wang GS. Comparison of Two-Bag Versus Three-Bag N-Acetylcysteine Regimens for Pediatric Acetaminophen Toxicity. Ann Pharmacother. 2023 01; 57(1):36-43.
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Akakpo JY, Ramachandran A, Curry SC, Rumack BH, Jaeschke H. Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose. Arch Toxicol. 2022 02; 96(2):453-465.
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Link SL, Rampon G, Osmon S, Scalzo AJ, Rumack BH. Reply to Comments on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series. Clin Toxicol (Phila). 2022 05; 60(5):668-669.
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Lebin JA, Mudan A. Comment on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series. Clin Toxicol (Phila). 2022 05; 60(5):665.
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