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Soluble Guanylyl Cyclase

"Soluble Guanylyl Cyclase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A mammalian enzyme composed of a heterodimer of alpha and beta subunits. Each subunit consists of four domains; N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four domains are homologous proteins with a similar conformation of functional domains. Soluble guanylate cyclase catalyzes the formation of cyclic GMP from GTP, and is a key enzyme of the nitric oxide signaling pathway involved in the regulation of a variety of biological and physiological processes in mammals.


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This graph shows the total number of publications written about "Soluble Guanylyl Cyclase" by people in this website by year, and whether "Soluble Guanylyl Cyclase" was a major or minor topic of these publications.
Bar chart showing 9 publications over 6 distinct years, with a maximum of 4 publications in 2014
To see the data from this visualization as text, click here.

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