 Receptors, Lysophosphatidic Acid
"Receptors, Lysophosphatidic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subfamily of lysophospholipid receptors with specificity for LYSOPHOSPHATIDIC ACIDS.
| Descriptor ID |
D049368
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| MeSH Number(s) |
D12.776.543.750.695.420.249
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| Concept/Terms |
Receptors, Lysophosphatidic Acid- Receptors, Lysophosphatidic Acid
- Acid Receptors, Lysophosphatidic
- Lysophosphatidic Acid Receptors
- Lysophosphatidic Acid Receptor
- Acid Receptor, Lysophosphatidic
- LPA Receptors
- Receptors, LPA
- Receptor, Lysophosphatidic Acid
LPA2 Receptor- LPA2 Receptor
- Receptor, LPA2
- Edg-4 Receptor
- Edg 4 Receptor
- Receptor, Edg-4
- Edg4 Protein
LPA3 Receptor- LPA3 Receptor
- Receptor, LPA3
- Edg-7 Receptor
- Edg 7 Receptor
- Receptor, Edg-7
- EDG7 Protein
LPA1 Receptor- LPA1 Receptor
- Receptor, LPA1
- vzg-1 Receptor
- Receptor, vzg-1
- vzg 1 Receptor
- LPA-1 Receptor
- LPA 1 Receptor
- Edg2 Protein
- edg-2 Receptor
- Receptor, edg-2
- edg 2 Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptors, Lysophosphatidic Acid".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Lysophosphatidic Acid".
This graph shows the total number of publications written about "Receptors, Lysophosphatidic Acid" by people in this website by year, and whether "Receptors, Lysophosphatidic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 1 | 2 | | 2022 | 2 | 1 | 3 | | 2023 | 0 | 3 | 3 |
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Below are the most recent publications written about "Receptors, Lysophosphatidic Acid" by people in Profiles.
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Turner JA, Fredrickson MA, D'Antonio M, Katsnelson E, MacBeth M, Van Gulick R, Chimed TS, McCarter M, D'Alessandro A, Robinson WA, Couts KL, Pelanda R, Klarquist J, Tobin RP, Torres RM. Lysophosphatidic acid modulates CD8 T cell immunosurveillance and metabolism to impair anti-tumor immunity. Nat Commun. 2023 06 03; 14(1):3214.
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Liu Q, Zhou Y, Cogan JD, Mitchell DB, Sheng Q, Zhao S, Bai Y, Ciombor KK, Sabusap CM, Malabanan MM, Markin CR, Douglas K, Ding G, Banovich NE, Nickerson DA, Blue EE, Bamshad MJ, Brown KK, Schwartz DA, Phillips JA, Martinez-Barricarte R, Salisbury ML, Shyr Y, Loyd JE, Kropski JA, Blackwell TS. The Genetic Landscape of Familial Pulmonary Fibrosis. Am J Respir Crit Care Med. 2023 05 15; 207(10):1345-1357.
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Torres RM, Turner JA, D'Antonio M, Pelanda R, Kremer KN. Regulation of CD8 T-cell signaling, metabolism, and cytotoxic activity by extracellular lysophosphatidic acid. Immunol Rev. 2023 08; 317(1):203-222.
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Axelsson Raja A, Wakimoto H, DeLaughter DM, Reichart D, Gorham J, Conner DA, Lun M, Probst CK, Sakai N, Knipe RS, Montesi SB, Shea B, Adam LP, Leinwand LA, Wan W, Choi ES, Lindberg EL, Patone G, Noseda M, H?bner N, Seidman CE, Tager AM, Seidman JG, Ho CY. Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model. Proc Natl Acad Sci U S A. 2022 07 12; 119(28):e2204174119.
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Heinzelmann K, Hu Q, Hu Y, Dobrinskikh E, Ansari M, Melo-Narv?ez MC, Ulke HM, Leavitt C, Mirita C, Trudeau T, Saal ML, Rice P, Gao B, Janssen WJ, Yang IV, Schiller HB, Vladar EK, Lehmann M, K?nigshoff M. Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis. Eur Respir J. 2022 06; 59(6).
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Kremer KN, Buser A, Thumkeo D, Narumiya S, Jacobelli J, Pelanda R, Torres RM. LPA suppresses T cell function by altering the cytoskeleton and disrupting immune synapse formation. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2118816119.
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Corte TJ, Lancaster L, Swigris JJ, Maher TM, Goldin JG, Palmer SM, Suda T, Ogura T, Minnich A, Zhan X, Tirucherai GS, Elpers B, Xiao H, Watanabe H, Smith RA, Charles ED, Fischer A. Phase 2 trial design of BMS-986278, a lysophosphatidic acid receptor 1 (LPA1) antagonist, in patients with idiopathic pulmonary fibrosis (IPF) or progressive fibrotic interstitial lung disease (PF-ILD). BMJ Open Respir Res. 2021 Dec; 8(1).
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Mathew D, Torres RM. Lysophosphatidic Acid Is an Inflammatory Lipid Exploited by Cancers for Immune Evasion via Mechanisms Similar and Distinct From CTLA-4 and PD-1. Front Immunol. 2020; 11:531910.
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Mathew D, Kremer KN, Strauch P, Tigyi G, Pelanda R, Torres RM. LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling. Front Immunol. 2019; 10:1159.
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Hu J, Oda SK, Shotts K, Donovan EE, Strauch P, Pujanauski LM, Victorino F, Al-Shami A, Fujiwara Y, Tigyi G, Oravecz T, Pelanda R, Torres RM. Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response. J Immunol. 2014 Jul 01; 193(1):85-95.
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