 Guanosine
"Guanosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purine nucleoside that has guanine linked by its N9 nitrogen to the C1 carbon of ribose. It is a component of ribonucleic acid and its nucleotides play important roles in metabolism. (From Dorland, 28th ed)
| Descriptor ID |
D006151
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| MeSH Number(s) |
D03.633.100.759.590.454 D13.570.583.454 D13.570.800.453
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Guanosine".
Below are MeSH descriptors whose meaning is more specific than "Guanosine".
This graph shows the total number of publications written about "Guanosine" by people in this website by year, and whether "Guanosine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 | | 1996 | 2 | 1 | 3 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 | | 2019 | 0 | 1 | 1 | | 2020 | 2 | 1 | 3 | | 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Guanosine" by people in Profiles.
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Gentry RC, Ide NA, Comunale VM, Hartwick EW, Kinz-Thompson CD, Gonzalez RL. The mechanism of mRNA cap recognition. Nature. 2025 Jan; 637(8046):736-743.
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Miller LG, Kim W, Schowe S, Taylor K, Han R, Jain V, Park R, Sherman M, Fang J, Ramirez H, Ellington A, Tamamis P, Resendiz MJE, Zhang YJ, Contreras L. Selective 8-oxo-rG stalling occurs in the catalytic core of polynucleotide phosphorylase (PNPase) during degradation. Proc Natl Acad Sci U S A. 2024 Nov 12; 121(46):e2317865121.
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Skinner A, Yang CH, Hincks K, Wang H, Resendiz MJE. Experimental and theoretical rationalization for the base pairing abilities of inosine, guanosine, adenosine, and their corresponding 8-oxo-7,8-dihydropurine, and 8-bromopurine analogues within A-form duplexes of RNA. Biopolymers. 2020 Dec; 111(12):e23410.
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Glennon MM, Skinner A, Krutsinger M, Resendiz MJE. Translesion synthesis by AMV, HIV, and MMLVreverse transcriptases using RNA templates containing inosine, guanosine, and their 8-oxo-7,8-dihydropurine derivatives. PLoS One. 2020; 15(8):e0235102.
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Kiggins C, Skinner A, Resendiz MJE. 7,8-Dihydro-8-oxoguanosine Lesions Inhibit the Theophylline Aptamer or Change Its Selectivity. Chembiochem. 2020 05 04; 21(9):1347-1355.
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Yanas A, Liu KF. RNA modifications and the link to human disease. Methods Enzymol. 2019; 626:133-146.
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Herbert C, Dzowo YK, Urban A, Kiggins CN, Resendiz MJE. Reactivity and Specificity of RNase T1, RNase A, and RNase H toward Oligonucleotides of RNA Containing 8-Oxo-7,8-dihydroguanosine. Biochemistry. 2018 05 22; 57(20):2971-2983.
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D'Alessandro A, Reisz JA, Culp-Hill R, Korsten H, van Bruggen R, de Korte D. Metabolic effect of alkaline additives and guanosine/gluconate in storage solutions for red blood cells. Transfusion. 2018 08; 58(8):1992-2002.
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Heischmann S, Christians U. Validation of the cell line LS180 as a model for study of the gastrointestinal toxicity of mycophenolic acid. Xenobiotica. 2018 May; 48(5):433-441.
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Jimmerson LC, Bushman LR, Ray ML, Anderson PL, Kiser JJ. A LC-MS/MS Method for Quantifying Adenosine, Guanosine and Inosine Nucleotides in Human Cells. Pharm Res. 2017 01; 34(1):73-83.
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