Hepatocyte Nuclear Factor 1
"Hepatocyte Nuclear Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor and homeodomain protein that regulates the expression of a large set of hepatic proteins including SERUM ALBUMIN; beta-fibrinogen; and ALPHA 1-ANTITRYPSIN. It is composed of hetero- or homo-dimers of HEPATOCYTE NUCLEAR FACTOR 1-ALPHA and HEPATOCYTE NUCLEAR FACTOR 1-BETA.
Descriptor ID |
D051537
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MeSH Number(s) |
D12.776.260.262.500 D12.776.260.400.218 D12.776.660.352.500 D12.776.930.318.500
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Concept/Terms |
Hepatocyte Nuclear Factor 1- Hepatocyte Nuclear Factor 1
- Hepatic Nuclear Factor 1
- HNF-1 Protein
- HNF 1 Protein
- HNF1 Transcription Factor
- Transcription Factor, HNF1
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Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 1".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 1" by people in this website by year, and whether "Hepatocyte Nuclear Factor 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 | 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 1" by people in Profiles.
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Bosse T, van Wering HM, Gielen M, Dowling LN, Fialkovich JJ, Piaseckyj CM, Gonzalez FJ, Akiyama TE, Montgomery RK, Grand RJ, Krasinski SD. Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo. Am J Physiol Gastrointest Liver Physiol. 2006 May; 290(5):G1016-24.
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Zhang DM, Zhou ZG, Weng JP, Li LR, Deng H, Zhang C, Jin P, Huang G, Peng J, Xiu LL, Wang JP, Yang L. [Etiological dissection in common anti-islet autoantibody-negative patients with type 1 diabetes]. Zhonghua Yi Xue Za Zhi. 2004 Aug 02; 84(15):1247-51.
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van Wering HM, Bosse T, Musters A, de Jong E, de Jong N, Hogen Esch CE, Boudreau F, Swain GP, Dowling LN, Montgomery RK, Grand RJ, Krasinski SD. Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4. Am J Physiol Gastrointest Liver Physiol. 2004 Oct; 287(4):G899-909.
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