 RNA Interference
"RNA Interference" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
| Descriptor ID |
D034622
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| MeSH Number(s) |
G05.308.203.374.790
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| Concept/Terms |
RNA Interference- RNA Interference
- Interference, RNA
- Gene Silencing, Post-Transcriptional
- Gene Silencing, Post Transcriptional
- RNA Silencing
- Post-Transcriptional Gene Silencing
- Post Transcriptional Gene Silencing
- Post-Transcriptional Gene Silencings
- Silencing, Post-Transcriptional Gene
- RNAi
- Posttranscriptional Gene Silencing
- Gene Silencing, Posttranscriptional
- Gene Silencings, Posttranscriptional
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Below are MeSH descriptors whose meaning is more general than "RNA Interference".
Below are MeSH descriptors whose meaning is more specific than "RNA Interference".
This graph shows the total number of publications written about "RNA Interference" by people in this website by year, and whether "RNA Interference" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 0 | 10 | 10 | | 2004 | 1 | 8 | 9 | | 2005 | 4 | 8 | 12 | | 2006 | 0 | 15 | 15 | | 2007 | 1 | 12 | 13 | | 2008 | 1 | 18 | 19 | | 2009 | 3 | 22 | 25 | | 2010 | 2 | 16 | 18 | | 2011 | 3 | 20 | 23 | | 2012 | 3 | 23 | 26 | | 2013 | 4 | 31 | 35 | | 2014 | 5 | 24 | 29 | | 2015 | 1 | 16 | 17 | | 2016 | 3 | 28 | 31 | | 2017 | 0 | 15 | 15 | | 2018 | 0 | 9 | 9 | | 2019 | 2 | 9 | 11 | | 2020 | 0 | 4 | 4 |
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Below are the most recent publications written about "RNA Interference" by people in Profiles.
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Ali A, Swanepoel CM, Winger QA, Rozance PJ, Anthony RV. Chorionic somatomammotropin RNA interference alters fetal liver glucose utilization. J Endocrinol. 2020 12; 247(3):251-262.
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Morrison JH, Miller C, Bankers L, Crameri G, Wang LF, Poeschla EM. A Potent Postentry Restriction to Primate Lentiviruses in a Yinpterochiropteran Bat. mBio. 2020 09 15; 11(5).
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Holers VM, Borodovsky A, Scheinman RI, Ho N, Ramirez JR, Dobó J, Gál P, Lindenberger J, Hansen AG, Desai D, Pihl R, Thiel S, Banda NK. Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D. Front Immunol. 2020; 11:201.
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Pires Da Silva J, Monceaux K, Guilbert A, Gressette M, Piquereau J, Novotova M, Ventura-Clapier R, Garnier A, Lemaire C. SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy. Cells. 2020 02 12; 9(2).
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Zhou X, Nair GG, Russ HA, Belair CD, Li ML, Shveygert M, Hebrok M, Blelloch R. LIN28B Impairs the Transition of hESC-Derived ß Cells from the Juvenile to Adult State. Stem Cell Reports. 2020 01 14; 14(1):9-20.
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Rao DM, Shackleford MT, Bordeaux EK, Sottnik JL, Ferguson RL, Yamamoto TM, Wellberg EA, Bitler BG, Sikora MJ. Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine O-acyltransferase or Wnt secretion. J Biol Chem. 2019 12 27; 294(52):19950-19966.
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Hinz TK, Kleczko EK, Singleton KR, Calhoun J, Marek LA, Kim J, Tan AC, Heasley LE. Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines. Mol Pharmacol. 2019 12; 96(6):862-870.
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Wade AK, Liu Y, Bethea MM, Toren E, Tse HM, Hunter CS. LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet ß-cell function. J Biol Chem. 2019 08 02; 294(31):11728-11740.
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Myat MM, Louis D, Mavrommatis A, Collins L, Mattis J, Ledru M, Verghese S, Su TT. Regulators of cell movement during development and regeneration in Drosophila. Open Biol. 2019 05 31; 9(5):180245.
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George LF, Pradhan SJ, Mitchell D, Josey M, Casey J, Belus MT, Fedder KN, Dahal GR, Bates EA. Ion Channel Contributions to Wing Development in Drosophila melanogaster. G3 (Bethesda). 2019 04 09; 9(4):999-1008.
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