 Mice, Inbred mdx
"Mice, Inbred mdx" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.
| Descriptor ID |
D018101
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| MeSH Number(s) |
B01.050.050.199.520.520.420.500 B01.050.150.900.649.313.992.635.505.500.400.420.500 B01.050.150.900.649.313.992.635.505.500.550.265
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| Concept/Terms |
Mice, Inbred mdx- Mice, Inbred mdx
- Inbred mdx Mice
- Mouse, Inbred mdx
- Inbred mdx Mouse
- Mice, mdx
- mdx Mice
- Mouse, mdx
- mdx Mouse
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Below are MeSH descriptors whose meaning is more general than "Mice, Inbred mdx".
- Organisms [B]
- Eukaryota [B01]
- Animals [B01.050]
- Animal Population Groups [B01.050.050]
- Animals, Laboratory [B01.050.050.199]
- Animals, Inbred Strains [B01.050.050.199.520]
- Mice, Inbred Strains [B01.050.050.199.520.520]
- Mice, Inbred C57BL [B01.050.050.199.520.520.420]
- Mice, Inbred mdx [B01.050.050.199.520.520.420.500]
- Chordata [B01.050.150]
- Vertebrates [B01.050.150.900]
- Mammals [B01.050.150.900.649]
- Eutheria [B01.050.150.900.649.313]
- Rodentia [B01.050.150.900.649.313.992]
- Muridae [B01.050.150.900.649.313.992.635]
- Murinae [B01.050.150.900.649.313.992.635.505]
- Mice [B01.050.150.900.649.313.992.635.505.500]
- Mice, Inbred Strains [B01.050.150.900.649.313.992.635.505.500.400]
- Mice, Inbred C57BL [B01.050.150.900.649.313.992.635.505.500.400.420]
- Mice, Inbred mdx [B01.050.150.900.649.313.992.635.505.500.400.420.500]
- Mice, Mutant Strains [B01.050.150.900.649.313.992.635.505.500.550]
- Mice, Inbred mdx [B01.050.150.900.649.313.992.635.505.500.550.265]
Below are MeSH descriptors whose meaning is more specific than "Mice, Inbred mdx".
This graph shows the total number of publications written about "Mice, Inbred mdx" by people in this website by year, and whether "Mice, Inbred mdx" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Mice, Inbred mdx" by people in Profiles.
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Mitani Y, Vagnozzi RJ, Millay DP. In vivo myomaker-mediated heterologous fusion and nuclear reprogramming. FASEB J. 2017 01; 31(1):400-411.
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Reyes NL, Banks GB, Tsang M, Margineantu D, Gu H, Djukovic D, Chan J, Torres M, Liggitt HD, Hirenallur-S DK, Hockenbery DM, Raftery D, Iritani BM. Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):424-9.
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Garbe CS, Buttgereit A, Schürmann S, Friedrich O. Automated multiscale morphometry of muscle disease from second harmonic generation microscopy using tensor-based image processing. IEEE Trans Biomed Eng. 2012 Jan; 59(1):39-44.
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Shi H, Boadu E, Mercan F, Le AM, Flach RJ, Zhang L, Tyner KJ, Olwin BB, Bennett AM. MAP kinase phosphatase-1 deficiency impairs skeletal muscle regeneration and exacerbates muscular dystrophy. FASEB J. 2010 Aug; 24(8):2985-97.
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Dabertrand F, Mironneau J, Henaff M, Macrez N, Morel JL. Comparison between gentamycin and exon skipping treatments to restore ryanodine receptor subtype 2 functions in mdx mouse duodenum myocytes. Eur J Pharmacol. 2010 Feb 25; 628(1-3):36-41.
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Morel JL, Dabertrand F, Fritz N, Henaff M, Mironneau J, Macrez N. The decrease of expression of ryanodine receptor sub-type 2 is reversed by gentamycin sulphate in vascular myocytes from mdx mice. J Cell Mol Med. 2009 Sep; 13(9B):3122-30.
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Peter AK, Marshall JL, Crosbie RH. Sarcospan reduces dystrophic pathology: stabilization of the utrophin-glycoprotein complex. J Cell Biol. 2008 Nov 03; 183(3):419-27.
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Deasy BM, Corsi KA, Huard J. [The sex of muscle stem cells: must it be taken into account?]. Med Sci (Paris). 2007 Oct; 23(10):798-800.
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Peter AK, Crosbie RH. Hypertrophic response of Duchenne and limb-girdle muscular dystrophies is associated with activation of Akt pathway. Exp Cell Res. 2006 Aug 01; 312(13):2580-91.
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Payne TR, Oshima H, Sakai T, Ling Y, Gharaibeh B, Cummins J, Huard J. Regeneration of dystrophin-expressing myocytes in the mdx heart by skeletal muscle stem cells. Gene Ther. 2005 Aug; 12(16):1264-74.
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