 Receptors, Antigen, T-Cell, alpha-beta
"Receptors, Antigen, T-Cell, alpha-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules.
| Descriptor ID |
D016693
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| MeSH Number(s) |
D12.776.543.750.705.816.824.825
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| Concept/Terms |
Receptors, Antigen, T-Cell, alpha-beta- Receptors, Antigen, T-Cell, alpha-beta
- Antigen Receptors, T-Cell, alpha-beta
- TcR alpha-beta
- TcR alpha beta
- alpha-beta, TcR
- T-Cell Receptor, alpha-beta
- T Cell Receptor, alpha beta
- alpha-beta T-Cell Receptor
- T-Cell Receptors, alpha-beta
- alpha-beta T-Cell Receptors
- Receptors, Antigen, T Cell, alpha beta
- T Cell Receptors, alpha beta
Antigen T Cell Receptor, beta Chain- Antigen T Cell Receptor, beta Chain
- T-Cell Receptors beta-Chain
- T Cell Receptors beta Chain
- beta-Chain, T-Cell Receptors
- T-Cell Receptor beta-Chain
- T Cell Receptor beta Chain
- beta-Chain, T-Cell Receptor
T-Cell Receptors alpha-Chain- T-Cell Receptors alpha-Chain
- T Cell Receptors alpha Chain
- alpha-Chain, T-Cell Receptors
- Antigen T Cell Receptor, alpha Chain
- T-Cell Receptor alpha-Chain
- T Cell Receptor alpha Chain
- alpha-Chain, T-Cell Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, T-Cell, alpha-beta".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Antigen [D12.776.543.750.705.816]
- Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]
- Receptors, Antigen, T-Cell, alpha-beta [D12.776.543.750.705.816.824.825]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, T-Cell, alpha-beta".
This graph shows the total number of publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in this website by year, and whether "Receptors, Antigen, T-Cell, alpha-beta" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1996 | 3 | 2 | 5 | | 1997 | 3 | 2 | 5 | | 1998 | 5 | 4 | 9 | | 1999 | 4 | 9 | 13 | | 2000 | 3 | 4 | 7 | | 2001 | 1 | 2 | 3 | | 2002 | 2 | 4 | 6 | | 2003 | 1 | 5 | 6 | | 2004 | 0 | 1 | 1 | | 2005 | 3 | 3 | 6 | | 2006 | 0 | 2 | 2 | | 2007 | 2 | 3 | 5 | | 2008 | 6 | 2 | 8 | | 2009 | 6 | 3 | 9 | | 2010 | 0 | 1 | 1 | | 2011 | 5 | 1 | 6 | | 2012 | 8 | 1 | 9 | | 2013 | 1 | 3 | 4 | | 2014 | 5 | 3 | 8 | | 2015 | 1 | 1 | 2 | | 2016 | 6 | 2 | 8 | | 2017 | 2 | 4 | 6 | | 2018 | 2 | 0 | 2 | | 2019 | 2 | 2 | 4 | | 2020 | 2 | 0 | 2 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 1 | 2 | | 2023 | 0 | 3 | 3 | | 2024 | 2 | 1 | 3 | | 2025 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in Profiles.
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Valen?a-Pereira F, Sheridan RM, Riemondy KA, Thornton T, Fang Q, Barret B, Paludo G, Thompson C, Collins P, Santiago M, Oltz E, Rincon M. Inactivation of GSK3? by Ser389 phosphorylation prevents thymocyte necroptosis and impacts Tcr repertoire diversity. Cell Death Differ. 2025 May; 32(5):880-898.
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Gonzalez NM, Zou D, Zeng Z, Feng FX, Zhang X, Sannes C, Gu A, Zu Y, Chen W. Transient Anti-TCR? mAb Treatment Induces CD4 + T Cell Exhaustion and Prolongs Survival in a Mouse Model of Systemic Lupus Erythematosus. Immunology. 2025 02; 174(2):239-246.
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Brown AJ, White J, Shaw L, Gross J, Slabodkin A, Kushner E, Greiff V, Matsuda J, Gapin L, Scott-Browne J, Kappler J, Marrack P. MHC heterozygosity limits T cell receptor variability in CD4 T cells. Sci Immunol. 2024 07 12; 9(97):eado5295.
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Danielson SM, Lefferts AR, Norman E, Regner EH, Schulz HM, Sansone-Poe D, Orlicky DJ, Kuhn KA. Myeloid Cells and Sphingosine-1-Phosphate Are Required for TCRa? Intraepithelial Lymphocyte Recruitment to the Colon Epithelium. J Immunol. 2024 Jun 01; 212(11):1843-1854.
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Kaneko S, Noguchi Y, Hatano M, Shimbo A, Irabu H, Furuno K, Iwata N, Fujimura J, Akamine K, Kobayashi A, Endo T, Morio T, Shimizu M. Clinical Usefulness of T-Cell Receptor V? Repertoire Analysis for Differentiating Multisystem Inflammatory Syndrome in Japanese Children From Toxic Shock Syndrome and Kawasaki Disease. Pediatr Infect Dis J. 2024 Apr 01; 43(4):e125-e127.
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Nishida J, Cristea S, Bodapati S, Puleo J, Bai G, Patel A, Hughes M, Snow C, Borges V, Ruddy KJ, Collins LC, Feeney AM, Slowik K, Bossuyt V, Dillon D, Lin NU, Partridge AH, Michor F, Polyak K. Peripheral blood TCR clonotype diversity as an age-associated marker of breast cancer progression. Proc Natl Acad Sci U S A. 2023 Dec 05; 120(49):e2316763120.
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Palmer WH, Leaton LA, Campos Codo A, Crute B, Roest J, Zhu S, Petersen J, Tobin RP, Hume PS, Stone M, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, Vivian JP, Trowsdale J, Getahun A, Rossjohn J, Cambier J, Loh L, Norman PJ. Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells. Sci Immunol. 2023 06 30; 8(84):eade5343.
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Mitchell AM, Baschal EE, McDaniel KA, Simmons KM, Pyle L, Waugh K, Steck AK, Yu L, Gottlieb PA, Rewers MJ, Nakayama M, Michels AW. Temporal development of T cell receptor repertoires during childhood in health and disease. JCI Insight. 2022 09 22; 7(18).
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Wang Y, Tsitsiklis A, Devoe S, Gao W, Chu HH, Zhang Y, Li W, Wong WK, Deane CM, Neau D, Slansky JE, Thomas PG, Robey EA, Dai S. Peptide Centric V? Specific Germline Contacts Shape a Specialist T Cell Response. Front Immunol. 2022; 13:847092.
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Born WK, O'Brien RL. Becoming aware of ?d T cells. Adv Immunol. 2022; 153:91-117.
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