 Receptors, Antigen, T-Cell, alpha-beta
"Receptors, Antigen, T-Cell, alpha-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules.
| Descriptor ID |
D016693
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| MeSH Number(s) |
D12.776.543.750.705.816.824.825
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| Concept/Terms |
Receptors, Antigen, T-Cell, alpha-beta- Receptors, Antigen, T-Cell, alpha-beta
- Antigen Receptors, T-Cell, alpha-beta
- TcR alpha-beta
- TcR alpha beta
- alpha-beta, TcR
- T-Cell Receptor, alpha-beta
- T Cell Receptor, alpha beta
- alpha-beta T-Cell Receptor
- T-Cell Receptors, alpha-beta
- alpha-beta T-Cell Receptors
- Receptors, Antigen, T Cell, alpha beta
- T Cell Receptors, alpha beta
Antigen T Cell Receptor, beta Chain- Antigen T Cell Receptor, beta Chain
- T-Cell Receptors beta-Chain
- T Cell Receptors beta Chain
- beta-Chain, T-Cell Receptors
- T-Cell Receptor beta-Chain
- T Cell Receptor beta Chain
- beta-Chain, T-Cell Receptor
T-Cell Receptors alpha-Chain- T-Cell Receptors alpha-Chain
- T Cell Receptors alpha Chain
- alpha-Chain, T-Cell Receptors
- Antigen T Cell Receptor, alpha Chain
- T-Cell Receptor alpha-Chain
- T Cell Receptor alpha Chain
- alpha-Chain, T-Cell Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, T-Cell, alpha-beta".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Antigen [D12.776.543.750.705.816]
- Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]
- Receptors, Antigen, T-Cell, alpha-beta [D12.776.543.750.705.816.824.825]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, T-Cell, alpha-beta".
This graph shows the total number of publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in this website by year, and whether "Receptors, Antigen, T-Cell, alpha-beta" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 1 | 2 | | 1993 | 1 | 4 | 5 | | 1994 | 4 | 1 | 5 | | 1995 | 1 | 0 | 1 | | 1996 | 4 | 1 | 5 | | 1997 | 4 | 2 | 6 | | 1998 | 3 | 4 | 7 | | 1999 | 2 | 9 | 11 | | 2000 | 3 | 3 | 6 | | 2001 | 1 | 3 | 4 | | 2002 | 1 | 2 | 3 | | 2003 | 1 | 2 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 5 | 2 | 7 | | 2009 | 6 | 2 | 8 | | 2010 | 0 | 2 | 2 | | 2011 | 4 | 1 | 5 | | 2012 | 8 | 2 | 10 | | 2013 | 1 | 2 | 3 | | 2014 | 4 | 2 | 6 | | 2015 | 1 | 1 | 2 | | 2016 | 3 | 0 | 3 | | 2017 | 2 | 4 | 6 | | 2019 | 2 | 2 | 4 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in Profiles.
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Brown IK, Dyjack N, Miller MM, Krovi H, Rios C, Woolaver R, Harmacek L, Tu TH, O'Connor BP, Danhorn T, Vestal B, Gapin L, Pinilla C, Seibold MA, Scott-Browne J, Santos RG, Reinhardt RL. Single cell analysis of host response to helminth infection reveals the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4+ T cell repertoire. PLoS Pathog. 2021 06; 17(6):e1009602.
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Loh L, Gherardin NA, Sant S, Grzelak L, Crawford JC, Bird NL, Koay HF, van de Sandt CE, Moreira ML, Lappas M, Allen EK, Crowe J, Loudovaris T, Flanagan KL, Quinn KM, Rossjohn J, Thomas PG, Eckle SBG, McCluskey J, Godfrey DI, Kedzierska K. Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRaß Clonotypes with Potent Antimicrobial Responses. J Immunol. 2020 03 01; 204(5):1119-1133.
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Marrack P. Obsessive-Compulsive Behavior Isn't Necessarily a Bad Thing. Annu Rev Immunol. 2020 04 26; 38:1-21.
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Krovi SH, Kappler JW, Marrack P, Gapin L. Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules. Proc Natl Acad Sci U S A. 2019 10 29; 116(44):22252-22261.
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Pan RY, Chu MT, Wang CW, Lee YS, Lemonnier F, Michels AW, Schutte R, Ostrov DA, Chen CB, Phillips EJ, Mallal SA, Mockenhaupt M, Bellón T, Tassaneeyakul W, White KD, Roujeau JC, Chung WH, Hung SI. Identification of drug-specific public TCR driving severe cutaneous adverse reactions. Nat Commun. 2019 08 08; 10(1):3569.
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Yusko E, Vignali M, Wilson RK, Mardis ER, Hodi FS, Horak C, Chang H, Woods DM, Robins H, Weber J. Association of Tumor Microenvironment T-cell Repertoire and Mutational Load with Clinical Outcome after Sequential Checkpoint Blockade in Melanoma. Cancer Immunol Res. 2019 03; 7(3):458-465.
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Nguyen THO, Sant S, Bird NL, Grant EJ, Clemens EB, Koutsakos M, Valkenburg SA, Gras S, Lappas M, Jaworowski A, Crowe J, Loh L, Kedzierska K. Perturbed CD8+ T cell immunity across universal influenza epitopes in the elderly. J Leukoc Biol. 2018 02; 103(2):321-339.
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Park CO, Fu X, Jiang X, Pan Y, Teague JE, Collins N, Tian T, O'Malley JT, Emerson RO, Kim JH, Jung Y, Watanabe R, Fuhlbrigge RC, Carbone FR, Gebhardt T, Clark RA, Lin CP, Kupper TS. Staged development of long-lived T-cell receptor aß TH17 resident memory T-cell population to Candida albicans after skin infection. J Allergy Clin Immunol. 2018 08; 142(2):647-662.
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Mitchell AM, Kaiser Y, Falta MT, Munson DJ, Landry LG, Eklund A, Nakayama M, Slansky JE, Grunewald J, Fontenot AP. Shared aß TCR Usage in Lungs of Sarcoidosis Patients with Löfgren's Syndrome. J Immunol. 2017 10 01; 199(7):2279-2290.
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Van Rhijn I, Iwany SK, Fodran P, Cheng TY, Gapin L, Minnaard AJ, Moody DB. CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails. Eur J Immunol. 2017 09; 47(9):1525-1534.
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