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Christopher Peter Calderon

TitleAsst Professor Adjunct
InstitutionUniversity of Colorado Boulder
DepartmentChemical & Biological Engin

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Greenblott DN, Zhang J, Calderon CP, Randolph TW. Machine learning approaches to root cause analysis, characterization, and monitoring of subvisible particles in monoclonal antibody formulations. Biotechnol Bioeng. 2022 12; 119(12):3596-3611. PMID: 36124935.
      View in: PubMed
    2. Thite NG, Ghazvini S, Wallace N, Feldman N, Calderon CP, Randolph TW. Machine Learning Analysis Provides Insight into Mechanisms of Protein Particle Formation Inside Containers During Mechanical Agitation. J Pharm Sci. 2022 10; 111(10):2730-2744. PMID: 35835184.
      View in: PubMed
    3. Calderon CP, Krhac Levacic A, Helbig C, Wuchner K, Menzen T. Combining Machine Learning and Backgrounded Membrane Imaging: A Case Study in Comparing and Classifying Different Types of Biopharmaceutically Relevant Particles. J Pharm Sci. 2022 09; 111(9):2422-2434. PMID: 35661758.
      View in: PubMed
    4. Calderon CP, Ripple DC, Srinivasan C, Ma Y, Carrier MJ, Randolph TW, O'Connor TF. Testing Precision Limits of Neural Network-Based Quality Control Metrics in High-Throughput Digital Microscopy. Pharm Res. 2022 Feb; 39(2):263-279. PMID: 35080706.
      View in: PubMed
    5. Movafaghi S, Daniels AL, Kelly MD, Witeof AE, Calderon CP, Randolph TW, Goodwin AP. Hydrogel Coatings on Container Surfaces Reduce Protein Aggregation Caused by Mechanical Stress and Cavitation. ACS Appl Bio Mater. 2021 09 20; 4(9):6946-6953. PMID: 35006994.
      View in: PubMed
    6. Sarfati R, Calderon CP, Schwartz DK. Enhanced Diffusive Transport in Fluctuating Porous Media. ACS Nano. 2021 04 27; 15(4):7392-7398. PMID: 33793204.
      View in: PubMed
    7. Witeof AE, Daniels AL, Rea LT, Movafaghi S, Kurtz K, Davis M, Eveland RW, Calderon CP, Randolph TW. Machine Learning and Accelerated Stress Approaches to Differentiate Potential Causes of Aggregation in Polyclonal Antibody Formulations During Shipping. J Pharm Sci. 2021 07; 110(7):2743-2752. PMID: 33647275.
      View in: PubMed
    8. Coscia BJ, Calderon CP, Shirts MR. Statistical Inference of Transport Mechanisms and Long Time Scale Behavior from Time Series of Solute Trajectories in Nanostructured Membranes. J Phys Chem B. 2020 09 17; 124(37):8110-8123. PMID: 32790365.
      View in: PubMed
    9. Daniels AL, Calderon CP, Randolph TW. Machine learning and statistical analyses for extracting and characterizing "fingerprints" of antibody aggregation at container interfaces from flow microscopy images. Biotechnol Bioeng. 2020 11; 117(11):3322-3335. PMID: 32667683.
      View in: PubMed
    10. Calderon CP, Daniels AL, Randolph TW. Deep Convolutional Neural Network Analysis of Flow Imaging Microscopy Data to Classify Subvisible Particles in Protein Formulations. J Pharm Sci. 2018 04; 107(4):999-1008. PMID: 29269269.
      View in: PubMed
    11. Calderon CP. Motion blur filtering: A statistical approach for extracting confinement forces and diffusivity from a single blurred trajectory. Phys Rev E. 2016 May; 93(5):053303. PMID: 27301001.
      View in: PubMed
    12. Calderon CP, Bloom K. Inferring Latent States and Refining Force Estimates via Hierarchical Dirichlet Process Modeling in Single Particle Tracking Experiments. PLoS One. 2015; 10(9):e0137633. PMID: 26384324.
      View in: PubMed
    13. Calderon CP. Correction: Calderon, C.P. Data-Driven Techniques for Detecting Dynamical State Changes in Noisily Measured 3D Single-Molecule Trajectories. Molecules 19, 18381-18398. Molecules. 2015 Feb 09; 20(2):2828-30. PMID: 25671332.
      View in: PubMed
    14. Calderon CP. Data-driven techniques for detecting dynamical state changes in noisily measured 3D single-molecule trajectories. Molecules. 2014 Nov 12; 19(11):18381-98. PMID: 25397733.
      View in: PubMed
    15. Calderon CP, Weiss LE, Moerner WE. Robust hypothesis tests for detecting statistical evidence of two-dimensional and three-dimensional interactions in single-molecule measurements. Phys Rev E Stat Nonlin Soft Matter Phys. 2014 May; 89(5):052705. PMID: 25353827.
      View in: PubMed
    16. Calderon CP, Thompson MA, Casolari JM, Paffenroth RC, Moerner WE. Quantifying transient 3D dynamical phenomena of single mRNA particles in live yeast cell measurements. J Phys Chem B. 2013 Dec 12; 117(49):15701-13. PMID: 24015725.
      View in: PubMed
    17. Calderon CP. Correcting for bias of molecular confinement parameters induced by small-time-series sample sizes in single-molecule trajectories containing measurement noise. Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Jul; 88(1):012707. PMID: 23944492.
      View in: PubMed
    18. Calderon CP. Estimation and Inference of Diffusion Coefficients in Complex Biomolecular Environments. J Chem Theory Comput. 2011 Feb 08; 7(2):280-90. PMID: 26596151.
      View in: PubMed
    19. Calderon CP. Detection of subtle dynamical changes induced by unresolved "conformational coordinates" in single-molecule trajectories via goodness-of-fit tests. J Phys Chem B. 2010 Mar 11; 114(9):3242-53. PMID: 20148536.
      View in: PubMed
    20. Calderon CP, Martinez JG, Carroll RJ, Sorensen DC. P-SPLINES USING DERIVATIVE INFORMATION. Multiscale Model Simul. 2010; 8(4):1562-1580. PMID: 21691592.
      View in: PubMed
    21. Calderon CP. Data-driven approach to decomposing complex enzyme kinetics with surrogate models. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Dec; 80(6 Pt 1):061118. PMID: 20365129.
      View in: PubMed
    22. Calderon CP, Harris NC, Kiang CH, Cox DD. Analyzing single-molecule manipulation experiments. J Mol Recognit. 2009 Sep-Oct; 22(5):356-62. PMID: 19479747.
      View in: PubMed
    23. Calderon CP, Arora K. Extracting Kinetic and Stationary Distribution Information from Short MD Trajectories via a Collection of Surrogate Diffusion Models. J Chem Theory Comput. 2009 Aug 11; 5(8):2192. PMID: 26613159.
      View in: PubMed
    24. Calderon CP, Janosi L, Kosztin I. Using stochastic models calibrated from nanosecond nonequilibrium simulations to approximate mesoscale information. J Chem Phys. 2009 Apr 14; 130(14):144908. PMID: 19368472.
      View in: PubMed
    25. Calderon CP, Chen WH, Lin KJ, Harris NC, Kiang CH. Quantifying DNA melting transitions using single-molecule force spectroscopy. J Phys Condens Matter. 2009 Jan 21; 21(3):34114. PMID: 20046972.
      View in: PubMed
    26. Calderon CP, Harris NC, Kiang CH, Cox DD. Quantifying multiscale noise sources in single-molecule time series. J Phys Chem B. 2009 Jan 08; 113(1):138-48. PMID: 19072043.
      View in: PubMed
    27. Calderon CP, Arora K. Extracting Kinetic and Stationary Distribution Information from Short MD Trajectories via a Collection of Surrogate Diffusion Models. J Chem Theory Comput. 2009 Jan 01; 5(1):47-58. PMID: 20046947.
      View in: PubMed
    28. Calderon CP, Chelli R. Approximating nonequilibrium processes using a collection of surrogate diffusion models. J Chem Phys. 2008 Apr 14; 128(14):145103. PMID: 18412481.
      View in: PubMed
    29. Calderon CP. On the use of local diffusion models for path ensemble averaging in potential of mean force computations. J Chem Phys. 2007 Feb 28; 126(8):084106. PMID: 17343439.
      View in: PubMed
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