Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Jefferson Matthew Taliaferro

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BioChem&Molecular Genetics

    Collapse Research 
    Collapse research activities and funding
    R01NS122911     (TALIAFERRO, JEFFERSON MATTHEW)Sep 19, 2023 - Aug 31, 2028
    NIH
    Mechanistic analysis of TDP-43-mediated RNA localization in neurons and its misregulation in ALS
    Role: Principal Investigator
    R35GM133385     (TALIAFERRO, JEFFERSON MATTHEW)Aug 15, 2019 - Jul 31, 2029
    NIH
    Understanding the regulatory language of RNA localization
    Role: Principal Investigator
    F32GM109562     (TALIAFERRO, JEFFERSON MATTHEW)Jan 1, 2014 - Dec 31, 2016
    NIH
    Genome-wide identification of mRNA localization motifs and factors
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Lo HG, Goering R, Kocere A, Lo J, Pockalny MC, White LK, Ramirez H, Martinez A, Jacobson S, Spitale RC, Pearson CG, Resendiz MJE, Mosimann C, Taliaferro JM. Quantification of subcellular RNA localization through direct detection of RNA oxidation. Nucleic Acids Res. 2025 Feb 27; 53(5). PMID: 40037712.
      View in: PubMed
    2. Lo HG, Goering R, Kocere A, Lo J, Pockalny MC, White LK, Ramirez H, Martinez A, Jacobson S, Spitale RC, Pearson CG, Resendiz MJE, Mosimann C, Taliaferro JM. Quantification of subcellular RNA localization through direct detection of RNA oxidation. bioRxiv. 2024 Nov 12. PMID: 39605352.
      View in: PubMed
    3. Lo J, Vaeth KF, Bhardwaj G, Mukherjee N, Russ HA, Moore JK, Taliaferro JM. The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites. bioRxiv. 2024 Aug 26. PMID: 39253515.
      View in: PubMed
    4. Chalivendra S, Shi S, Li X, Kuang Z, Giovinazzo J, Zhang L, Rossi J, Wang J, Saviola AJ, Welty R, Liu S, Vaeth KF, Zhou ZH, Hansen KC, Taliaferro JM, Zhao R. Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast. RNA. 2024 07 16; 30(8):1070-1088. PMID: 38688558.
      View in: PubMed
    5. Lo HG, Pearson CG, Taliaferro JM. Differential subcellular localization of ASPM RNA and protein. MicroPubl Biol. 2024; 2024. PMID: 38344067.
      View in: PubMed
    6. Eiler DR, Wimberly BT, Bilodeau DY, Taliaferro JM, Reigan P, Rissland OS, Kieft JS. The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure. 2024 Apr 04; 32(4):400-410.e4. PMID: 38242118.
      View in: PubMed
    7. Goering R, Arora A, Pockalny MC, Taliaferro JM. RNA localization mechanisms transcend cell morphology. Elife. 2023 03 03; 12. PMID: 36867563.
      View in: PubMed
    8. Espinosa S, De Bortoli F, Li X, Rossi J, Wagley ME, Lo HG, Taliaferro JM, Zhao R. Human PRPF39 is an alternative splicing factor recruiting U1 snRNP to weak 5' splice sites. RNA. 2022 Oct 31. PMID: 36316087.
      View in: PubMed
    9. Arora A, Castro-Gutierrez R, Moffatt C, Eletto D, Becker R, Brown M, Moor AE, Russ HA, Taliaferro JM. High-throughput identification of RNA localization elements in neuronal cells. Nucleic Acids Res. 2022 10 14; 50(18):10626-10642. PMID: 36107770.
      View in: PubMed
    10. Lee S, Chen YC, Gillen AE, Taliaferro JM, Deplancke B, Li H, Lai EC. Diverse cell-specific patterns of alternative polyadenylation in Drosophila. Nat Commun. 2022 09 13; 13(1):5372. PMID: 36100597.
      View in: PubMed
    11. Lo HG, Engel KL, Goering R, Li Y, Spitale RC, Taliaferro JM. Halo-seq: An RNA Proximity Labeling Method for the Isolation and Analysis of Subcellular RNA Populations. Curr Protoc. 2022 May; 2(5):e424. PMID: 35532287.
      View in: PubMed
    12. Engel KL, Lo HG, Goering R, Li Y, Spitale RC, Taliaferro JM. Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq. Nucleic Acids Res. 2022 02 28; 50(4):e24. PMID: 34875090.
      View in: PubMed
    13. Arora A, Goering R, Lo HYG, Lo J, Moffatt C, Taliaferro JM. The Role of Alternative Polyadenylation in the Regulation of Subcellular RNA Localization. Front Genet. 2021; 12:818668. PMID: 35096024.
      View in: PubMed
    14. Taliaferro JM. Transcriptome-scale methods for uncovering subcellular RNA localization mechanisms. Biochim Biophys Acta Mol Cell Res. 2022 04; 1869(4):119202. PMID: 34998919.
      View in: PubMed
    15. Arora A, Goering R, Velez PT, Taliaferro JM. Visualization and Quantification of Subcellular RNA Localization Using Single-Molecule RNA Fluorescence In Situ Hybridization. Methods Mol Biol. 2022; 2404:247-266. PMID: 34694613.
      View in: PubMed
    16. Goering R, Engel KL, Gillen AE, Fong N, Bentley DL, Taliaferro JM. LABRAT reveals association of alternative polyadenylation with transcript localization, RNA binding protein expression, transcription speed, and cancer survival. BMC Genomics. 2021 Jun 26; 22(1):476. PMID: 34174817.
      View in: PubMed
    17. Gillen AE, Goering R, Taliaferro JM. Quantifying alternative polyadenylation in RNAseq data with LABRAT. Methods Enzymol. 2021; 655:245-263. PMID: 34183124.
      View in: PubMed
    18. Hudish LI, Bubak A, Triolo TM, Niemeyer CS, Lorberbaum DS, Sussel L, Nagel M, Taliaferro JM, Russ HA. Modeling Hypoxia-Induced Neuropathies Using a Fast and Scalable Human Motor Neuron Differentiation System. Stem Cell Reports. 2021 Apr 13; 16(4):1009. PMID: 33852882.
      View in: PubMed
    19. Raj N, McEachin ZT, Harousseau W, Zhou Y, Zhang F, Merritt-Garza ME, Taliaferro JM, Kalinowska M, Marro SG, Hales CM, Berry-Kravis E, Wolf-Ochoa MW, Martinez-Cerde?o V, Wernig M, Chen L, Klann E, Warren ST, Jin P, Wen Z, Bassell GJ. Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis. Cell Rep. 2021 04 13; 35(2):108991. PMID: 33852833.
      View in: PubMed
    20. Lee S, Wei L, Zhang B, Goering R, Majumdar S, Wen J, Taliaferro JM, Lai EC. ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing. PLoS Genet. 2021 04; 17(4):e1009439. PMID: 33826609.
      View in: PubMed
    21. Goering R, Hudish LI, Guzman BB, Raj N, Bassell GJ, Russ HA, Dominguez D, Taliaferro JM. FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences. Elife. 2020 06 08; 9. PMID: 32510328.
      View in: PubMed
    22. Hudish LI, Bubak A, Triolo TM, Niemeyer CS, Lorberbaum DS, Sussel L, Nagel M, Taliaferro JM, Russ HA. Modeling Hypoxia-Induced Neuropathies Using a Fast and Scalable Human Motor Neuron Differentiation System. Stem Cell Reports. 2020 06 09; 14(6):1033-1043. PMID: 32386561.
      View in: PubMed
    23. Engel KL, Arora A, Goering R, Lo HG, Taliaferro JM. Mechanisms and consequences of subcellular RNA localization across diverse cell types. Traffic. 2020 06; 21(6):404-418. PMID: 32291836.
      View in: PubMed
    24. Gillette CM, Hazegh KE, Nemkov T, Stefanoni D, D'Alessandro A, Taliaferro JM, Reis T. Gene-Diet Interactions: Dietary Rescue of Metabolic Effects in spen-Depleted Drosophila melanogaster. Genetics. 2020 04; 214(4):961-975. PMID: 32107279.
      View in: PubMed
    25. Narula A, Ellis J, Taliaferro JM, Rissland OS. Coding regions affect mRNA stability in human cells. RNA. 2019 12; 25(12):1751-1764. PMID: 31527111.
      View in: PubMed
    26. Taliaferro JM. Classical and emerging techniques to identify and quantify localized RNAs. Wiley Interdiscip Rev RNA. 2019 09; 10(5):e1542. PMID: 31044542.
      View in: PubMed
    27. Rothenberg DA, Taliaferro JM, Huber SM, Begley TJ, Dedon PC, White FM. A Proteomics Approach to Profiling the Temporal Translational Response to Stress and Growth. iScience. 2018 Nov 30; 9:367-381. PMID: 30466063.
      View in: PubMed
    28. Wang ET, Taliaferro JM, Lee JA, Sudhakaran IP, Rossoll W, Gross C, Moss KR, Bassell GJ. Dysregulation of mRNA Localization and Translation in Genetic Disease. J Neurosci. 2016 11 09; 36(45):11418-11426. PMID: 27911744.
      View in: PubMed
    29. Taliaferro JM, Lambert NJ, Sudmant PH, Dominguez D, Merkin JJ, Alexis MS, Bazile C, Burge CB. RNA Sequence Context Effects Measured In?Vitro Predict In?Vivo Protein Binding and Regulation. Mol Cell. 2016 10 20; 64(2):294-306. PMID: 27720642.
      View in: PubMed
    30. Wang Q, Taliaferro JM, Klibaite U, Hilgers V, Shaevitz JW, Rio DC. The PSI-U1 snRNP interaction regulates male mating behavior in Drosophila. Proc Natl Acad Sci U S A. 2016 May 10; 113(19):5269-74. PMID: 27114556.
      View in: PubMed
    31. Taliaferro JM, Vidaki M, Oliveira R, Olson S, Zhan L, Saxena T, Wang ET, Graveley BR, Gertler FB, Swanson MS, Burge CB. Distal Alternative Last Exons Localize mRNAs to Neural Projections. Mol Cell. 2016 Mar 17; 61(6):821-33. PMID: 26907613.
      View in: PubMed
    32. Taliaferro JM, Wang ET, Burge CB. Genomic analysis of RNA localization. RNA Biol. 2014; 11(8):1040-50. PMID: 25483039.
      View in: PubMed
    33. Taliaferro JM, Marwha D, Aspden JL, Mavrici D, Cheng NE, Kohlstaedt LA, Rio DC. The Drosophila splicing factor PSI is phosphorylated by casein kinase II and tousled-like kinase. PLoS One. 2013; 8(2):e56401. PMID: 23437125.
      View in: PubMed
    34. Taliaferro JM, Aspden JL, Bradley T, Marwha D, Blanchette M, Rio DC. Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression. Genes Dev. 2013 Feb 15; 27(4):378-89. PMID: 23392611.
      View in: PubMed
    35. Stolfi A, Wagner E, Taliaferro JM, Chou S, Levine M. Neural tube patterning by Ephrin, FGF and Notch signaling relays. Development. 2011 Dec; 138(24):5429-39. PMID: 22110057.
      View in: PubMed
    36. Taliaferro JM, Alvarez N, Green RE, Blanchette M, Rio DC. Evolution of a tissue-specific splicing network. Genes Dev. 2011 Mar 15; 25(6):608-20. PMID: 21406555.
      View in: PubMed
    Taliaferro's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (161) concept(s)
    _
    Co-Authors Expand Description
    See all (24) people
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department

    Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)