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Juan Pablo Idrovo

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-SRG

    Collapse Research 
    Collapse research activities and funding
    R01GM153949     (IDROVO, JUAN PABLO)Sep 10, 2024 - Jun 30, 2029
    NIH
    Aging, Burn Trauma, and Liver Damage
    Role: Principal Investigator
    K08GM134185     (IDROVO, JUAN PABLO)Sep 15, 2019 - Aug 31, 2024
    NIH
    Hepatic Response in Advance Age after Burn Injury
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Meza Monge K, Qualman AC, Pratap A, Kovacs EJ, Idrovo JP. Sirtuin Expression in Age-Associated Hepatic Response to Burn Trauma: Translational and Clinical Insights From a Murine Model. Cureus. 2025 Apr; 17(4):e82663. PMID: 40400796.
      View in: PubMed
    2. Meza Monge K, Rivera Guevara AN, Melara Ruiz NS, Mendez JLA, Idrovo JP. Maternal and Fetal Complications Associated With Gestational Diabetes Mellitus in a Nicaraguan Tertiary Care Hospital: A Cross-Sectional Study. Cureus. 2025 Apr; 17(4):e81901. PMID: 40342479.
      View in: PubMed
    3. Muro I, Qualman AC, Meza Monge K, Pratap A, Kovacs EJ, Idrovo JP. Delayed hepatic response and impaired cytokine dynamics in aged mice following burn injury: Implications for elderly patient care. PLoS One. 2025; 20(2):e0316813. PMID: 39992944.
      View in: PubMed
    4. Meza Monge K, Ardon-Lopez A, Pratap A, Idrovo JP. Targeting Inflammation After Hemorrhagic Shock as a Molecular and Experimental Journey to Improve Outcomes: A Review. Cureus. 2025 Jan; 17(1):e77776. PMID: 39981454.
      View in: PubMed
    5. Pratap A, Monge KM, Qualman AC, Kovacs EJ, Idrovo JP. Burn-induced mitochondrial dysfunction in hepatocytes: The role of methylation-controlled J protein silencing. J Trauma Acute Care Surg. 2025 Feb 01; 98(2):204-211. PMID: 39760651.
      View in: PubMed
    6. Meza Monge K, Rosa C, Sublette C, Pratap A, Kovacs EJ, Idrovo JP. Navigating Hemorrhagic Shock: Biomarkers, Therapies, and Challenges in Clinical Care. Biomedicines. 2024 Dec 17; 12(12). PMID: 39767770.
      View in: PubMed
    7. Pratap A, Qualman A, Garrett H, Westbrook L, The E, Mitra S, Cordero M, Monge KM, Idrovo JP, Chauhan A, Cheng L, Cohen MJ, Mungo B, Wani S, Meguid RA, McCarter MD, Meng X. Silencing Glypican-1 enhances the antitumor effects of Pictilisib via downregulating PI3K/Akt/ERK signaling in chemo-resistant esophageal adenocarcinoma. Mol Cell Oncol. 2023; 10(1):2238873. PMID: 37649964.
      View in: PubMed
    8. Walrath T, Najarro KM, Giesy LE, Khair S, Frank DN, Robertson CE, Orlicky DJ, Quillinan N, Idrovo JP, McMahan RH, Kovacs EJ. REMOTE BURN INJURY IN AGED MICE INDUCES COLONIC LYMPHOID AGGREGATE EXPANSION AND DYSBIOSIS OF THE FECAL MICROBIOME WHICH CORRELATES WITH NEUROINFLAMMATION. Shock. 2023 10 01; 60(4):585-593. PMID: 37548929.
      View in: PubMed
    9. Pratap A, Qualman A, Garrett H, The E, Chauhan A, Idrovo JP, Cheng L, Wani S, Meguid RA, Meng X. Targeting Glypican-1 Reverses Resistance to 5-Fluorouracil in Esophageal Adenocarcinoma Cells. Anticancer Res. 2023 Aug; 43(8):3411-3418. PMID: 37500147.
      View in: PubMed
    10. Malachowska B, Yang WL, Qualman A, Muro I, Boe DM, Lampe JN, Kovacs EJ, Idrovo JP. Transcriptomics, metabolomics, and in-silico drug predictions for liver damage in young and aged burn victims. Commun Biol. 2023 06 02; 6(1):597. PMID: 37268765.
      View in: PubMed
    11. Muro I, Qualman AC, Kovacs EJ, Idrovo JP. Burn-Induced Apoptosis in the Livers of Aged Mice Is Associated With Caspase Cleavage of Bcl-xL. J Surg Res. 2023 10; 290:147-155. PMID: 37267704.
      View in: PubMed
    12. Choy K, Dyamenahalli KU, Khair S, Colborn KL, Wiktor AJ, Idrovo JP, McMahan RH, Burnham EL, Kovacs EJ. Aberrant inflammatory responses in intoxicated burn-injured patients parallel impaired cognitive function. Alcohol. 2023 06; 109:35-41. PMID: 36690221.
      View in: PubMed
    13. Walrath T, McMahan RH, Idrovo JP, Quillinan N, Kovacs EJ. Cutaneous burn injury induces neuroinflammation and reactive astrocyte activation in the hippocampus of aged mice. Exp Gerontol. 2022 11; 169:111975. PMID: 36208823.
      View in: PubMed
    14. Dyamenahalli K, Choy K, Frank DN, Najarro K, Boe D, Colborn KL, Idrovo JP, Wagner AL, Wiktor AJ, Afshar M, Burnham EL, McMahan RH, Kovacs EJ. Age and Injury Size Influence the Magnitude of Fecal Dysbiosis in Adult Burn Patients. J Burn Care Res. 2022 09 01; 43(5):1145-1153. PMID: 35020913.
      View in: PubMed
    15. McMahan RH, Boe DM, Walrath TM, Idrovo JP, Kovacs EJ. Aging, Cutaneous Burn Injury and Multi-Organ Complications: The Role of the Gut. Adv Geriatr Med Res. 2022; 4(2). PMID: 35913894.
      View in: PubMed
    16. Najarro KM, Boe DM, Walrath TM, Mullen JE, Paul MT, Frankel JH, Hulsebus HJ, Idrovo JP, McMahan RH, Kovacs EJ. Advanced age exacerbates intestinal epithelial permeability after burn injury in mice. Exp Gerontol. 2022 02; 158:111654. PMID: 34915110.
      View in: PubMed
    17. Guo H, Idrovo JP, Cao J, Roychoudhury S, Navale P, Auguste LJ, Bhuiya T, Sheikh-Fayyaz S. Human Papillomavirus (HPV) Detection by Chromogenic In Situ Hybridization (CISH) and p16 Immunohistochemistry (IHC) in Breast Intraductal Papilloma and Breast Carcinoma. Clin Breast Cancer. 2021 12; 21(6):e638-e646. PMID: 34059433.
      View in: PubMed
    18. Idrovo JP, Boe DM, Kaahui S, Walrath T, McMahan RH, Kovacs EJ. Advanced age heightens hepatic damage in a murine model of scald burn injury. J Trauma Acute Care Surg. 2021 04 01; 90(4):731-737. PMID: 33306599.
      View in: PubMed
    19. Carmichael H, Wright FL, McIntyre RC, Vogler T, Urban S, Jolley SE, Burnham EL, Firth W, Velopulos CG, Idrovo JP. Early ventilator liberation and decreased sedation needs after tracheostomy in patients with COVID-19 infection. Trauma Surg Acute Care Open. 2021; 6(1):e000591. PMID: 34192162.
      View in: PubMed
    20. Pormohammad A, Ghorbani S, Khatami A, Razizadeh MH, Alborzi E, Zarei M, Idrovo JP, Turner RJ. Comparison of influenza type A and B with COVID-19: A global systematic review and meta-analysis on clinical, laboratory and radiographic findings. Rev Med Virol. 2021 05; 31(3):e2179. PMID: 33035373.
      View in: PubMed
    21. Walrath T, Dyamenahalli KU, Hulsebus HJ, McCullough RL, Idrovo JP, Boe DM, McMahan RH, Kovacs EJ. Age-related changes in intestinal immunity and the microbiome. J Leukoc Biol. 2021 06; 109(6):1045-1061. PMID: 33020981.
      View in: PubMed
    22. Idrovo JP, Boe DM, Kaahui S, Yang WL, Kovacs EJ. Hepatic inflammation after burn injury is associated with necroptotic cell death signaling. J Trauma Acute Care Surg. 2020 10; 89(4):768-774. PMID: 33017135.
      View in: PubMed
    23. Pormohammad A, Ghorbani S, Baradaran B, Khatami A, J Turner R, Mansournia MA, Kyriacou DN, Idrovo JP, Bahr NC. Clinical characteristics, laboratory findings, radiographic signs and outcomes of 61,742 patients with confirmed COVID-19 infection: A systematic review and meta-analysis. Microb Pathog. 2020 Oct; 147:104390. PMID: 32681968.
      View in: PubMed
    24. Pormohammad A, Ghorbani S, Khatami A, Farzi R, Baradaran B, Turner DL, Turner RJ, Bahr NC, Idrovo JP. Comparison of confirmed COVID-19 with SARS and MERS cases - Clinical characteristics, laboratory findings, radiographic signs and outcomes: A systematic review and meta-analysis. Rev Med Virol. 2020 07; 30(4):e2112. PMID: 32502331.
      View in: PubMed
    25. Idrovo JP, Shults JA, Curtis BJ, Chen MM, Kovacs EJ. Alcohol Intoxication and the Postburn Gastrointestinal Hormonal Response. J Burn Care Res. 2019 10 16; 40(6):785-791. PMID: 31102437.
      View in: PubMed
    26. Idrovo JP, Jacob A, Yang WL, Wang Z, Yen HT, Nicastro J, Coppa GF, Wang P. A deficiency in cold-inducible RNA-binding protein accelerates the inflammation phase and improves wound healing. Int J Mol Med. 2016 Feb; 37(2):423-8. PMID: 26743936.
      View in: PubMed
    27. Idrovo JP, Yang WL, Jacob A, Corbo L, Nicastro J, Coppa GF, Wang P. Inhibition of lipogenesis reduces inflammation and?organ injury in sepsis. J Surg Res. 2016 Jan; 200(1):242-9. PMID: 26216747.
      View in: PubMed
    28. Idrovo JP, Yang WL, Jacob A, Aziz M, Nicastro J, Coppa GF, Wang P. AICAR attenuates organ injury and inflammatory response after intestinal ischemia and reperfusion. Mol Med. 2015 Mar 19; 20:676-83. PMID: 25611433.
      View in: PubMed
    29. Idrovo JP, Yang WL, Jacob A, Ajakaiye MA, Cheyuo C, Wang Z, Prince JM, Nicastro J, Coppa GF, Wang P. Combination of adrenomedullin with its binding protein accelerates cutaneous wound healing. PLoS One. 2015; 10(3):e0120225. PMID: 25781901.
      View in: PubMed
    30. Idrovo JP, Yang WL, Nicastro J, Coppa GF, Wang P. Stimulation of carnitine palmitoyltransferase 1 improves renal function and attenuates tissue damage after ischemia/reperfusion. J Surg Res. 2012 Sep; 177(1):157-64. PMID: 22698429.
      View in: PubMed
    31. Idrovo JP, Yang WL, Matsuda A, Nicastro J, Coppa GF, Wang P. Post-treatment with the combination of 5-aminoimidazole-4-carboxyamide ribonucleoside and carnitine improves renal function after ischemia/reperfusion injury. Shock. 2012 Jan; 37(1):39-46. PMID: 21841537.
      View in: PubMed
    32. Idrovo JP, Teo TY, Shah KG, Wang P, Bhaskaran MC, Pellerito J, Putterman D, Nicastro J, Coppa GF, Molmenti EP. Transitory peaked waveforms with elevated velocities in Doppler sonography after renal transplant. Exp Clin Transplant. 2011 Dec; 9(6):421-4. PMID: 22142052.
      View in: PubMed
    33. Shah KG, Molmenti EP, Idrovo JP, Nicastro J, Coppa G. Primary gallbladder lymphoma. Am Surg. 2011 Mar; 77(3):360-1. PMID: 21375853.
      View in: PubMed
    34. Shah KG, Idrovo JP, Nicastro J, McMullen HF, Molmenti EP, Coppa G. A retrospective analysis of the incidence of hemolysis in type and screen specimens from trauma patients. Int J Angiol. 2009; 18(4):182-3. PMID: 22477549.
      View in: PubMed
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