Item Type | Name |
Academic Article
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A potential role for interleukin-7 in T-cell homeostasis.
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Concept
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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Concept
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Hematopoietic Stem Cells
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Concept
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Precursor Cells, B-Lymphoid
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Concept
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Lymphoma, Large B-Cell, Diffuse
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Concept
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Cell Lineage
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Concept
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Receptors, Antigen, T-Cell
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Concept
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Neoplastic Stem Cells
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Concept
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Hematopoietic Stem Cell Transplantation
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Concept
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Cell Division
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Concept
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Leukemia, B-Cell
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Concept
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Cell Adhesion Molecules
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Concept
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Cell Survival
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Concept
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Receptors, Cell Surface
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Concept
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Cell Adhesion
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Concept
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Cell Cycle
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Concept
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Cell Membrane
|
Concept
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Cell Culture Techniques
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Concept
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Clone Cells
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Concept
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Peripheral Blood Stem Cell Transplantation
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Concept
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K562 Cells
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Concept
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Lymphoma, B-Cell
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Concept
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Dendritic Cells
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Concept
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Stem Cell Transplantation
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Concept
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Antigen-Presenting Cells
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Concept
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Stromal Cells
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Concept
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Cell Line
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Concept
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Tumor Cells, Cultured
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Concept
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Carcinoma, Transitional Cell
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Concept
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Cell Differentiation
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Concept
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Bone Marrow Cells
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Concept
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Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
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Concept
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Myeloid Cells
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Concept
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Killer Cells, Natural
|
Concept
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Cell Line, Tumor
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Concept
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Cell Polarity
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Concept
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Cells, Cultured
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Concept
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Cell Separation
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Concept
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Cell Proliferation
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Concept
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Stem Cell Niche
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Academic Article
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T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial.
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Academic Article
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Analysis of pediatric autologous PBSC apheresis and transplant: age is a major factor affecting post-transplant toxicity.
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Academic Article
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Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets.
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Academic Article
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Harnessing the biology of IL-7 for therapeutic application.
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Academic Article
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Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy.
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Academic Article
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Dose-adjusted EPOCH-rituximab combined with fludarabine provides an effective bridge to reduced-intensity allogeneic hematopoietic stem-cell transplantation in patients with lymphoid malignancies.
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Academic Article
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Children as hematopoietic cell donors in research: when is it approvable?
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Academic Article
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CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy.
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Academic Article
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IL-7 in allogeneic transplant: clinical promise and potential pitfalls.
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Academic Article
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Association of serum interleukin-7 levels with the development of acute graft-versus-host disease.
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Academic Article
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Cytokine signals in T-cell homeostasis.
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Academic Article
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The functional interplay between systemic cancer and the hematopoietic stem cell niche.
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Academic Article
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Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways.
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Academic Article
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Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001.
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Academic Article
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Procalcitonin and cytokine profiles in engraftment syndrome in pediatric stem cell transplantation.
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Academic Article
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IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation.
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Academic Article
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Interleukin-7 restores immunity in athymic T-cell-depleted hosts.
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Academic Article
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Reduced-intensity allogeneic stem cell transplantation in children and young adults with ultrahigh-risk pediatric sarcomas.
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Academic Article
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Minor antigen distribution predicts site-specific graft-versus-tumor activity of adoptively transferred, minor antigen-specific CD8 T Cells.
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Academic Article
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Hematopoietic stem cell donation in children: a review of the sibling donor experience.
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Academic Article
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Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection.
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Academic Article
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Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD.
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Academic Article
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Generation of clinical-grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of human B-cell malignancies.
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Academic Article
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Sibling stem cell donor experiences at a single institution.
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Academic Article
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Autologous lymphapheresis for the production of chimeric antigen receptor T?cells.
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Academic Article
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Myeloablative hematopoietic stem cell transplantation improves survival but is not curative in a pre-clinical model of myelodysplastic syndrome.
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Academic Article
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IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells.
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Academic Article
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Absence of Replication-Competent Lentivirus in the Clinic: Analysis of Infused T Cell Products.
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Academic Article
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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.
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Academic Article
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Elutriated lymphocytes for manufacturing chimeric antigen receptor T cells.
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Academic Article
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Immune reconstitution following hematopoietic progenitor cell transplantation: challenges for the future.
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Academic Article
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Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell.
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Academic Article
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Interleukin-7: from bench to clinic.
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Academic Article
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Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool.
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Academic Article
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CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
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Academic Article
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Murine allogeneic CD19 CAR T cells harbor potent antileukemic activity but have the potential to mediate lethal GVHD.
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Academic Article
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The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance.
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Academic Article
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TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance.
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Academic Article
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Self-enabling T cells.
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Academic Article
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Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation.
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Academic Article
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Eradication of B-ALL using chimeric antigen receptor-expressing T cells targeting the TSLPR oncoprotein.
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Academic Article
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Background to hematopoietic cell transplantation, including post transplant immune recovery.
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Academic Article
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A pan inhibitor of DASH family enzymes induces immunogenic modulation and sensitizes murine and human carcinoma cells to antigen-specific cytotoxic T lymphocyte killing: implications for combination therapy with cancer vaccines.
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Academic Article
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Myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation: diagnostic and therapeutic challenges.
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Academic Article
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A pan-inhibitor of DASH family enzymes induces immune-mediated regression of murine sarcoma and is a potent adjuvant to dendritic cell vaccination and adoptive T-cell therapy.
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Academic Article
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Induction of Immune Response after Allogeneic Wilms' Tumor 1 Dendritic Cell Vaccination and Donor Lymphocyte Infusion in Patients with Hematologic Malignancies and Post-Transplantation Relapse.
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Academic Article
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Expanding options to improve outcomes following hematopoietic stem cell transplantation.
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Academic Article
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Extending the horizon for cell-based immunotherapy by understanding the mechanisms of action of photopheresis.
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Academic Article
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Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches.
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Academic Article
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Research involving pediatric stem cell donors: A way forward.
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Academic Article
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Unusual sites of extraskeletal metastases of Ewing sarcoma after allogeneic hematopoietic stem cell transplantation.
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Academic Article
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Flt3 ligand enhances thymic-dependent and thymic-independent immune reconstitution.
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Academic Article
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A role for thymic stromal lymphopoietin in CD4(+) T cell development.
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Academic Article
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Radiofrequency ablation induces antigen-presenting cell infiltration and amplification of weak tumor-induced immunity.
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Academic Article
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Bioinformatic description of immunotherapy targets for pediatric T-cell leukemia and the impact of normal gene sets used for comparison.
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Academic Article
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Bone marrow deficient in IFN-{gamma} signaling selectively reverses GVHD-associated immunosuppression and enhances a tumor-specific GVT effect.
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Academic Article
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Extracorporeal photopheresis attenuates murine graft-versus-host disease via bone marrow-derived interleukin-10 and preserves responses to dendritic cell vaccination.
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Academic Article
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Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase.
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Academic Article
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Escape from immune surveillance does not result in tolerance to tumor-associated antigens.
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Academic Article
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Recombinant interleukin-7 induces proliferation of naive macaque CD4+ and CD8+ T cells in vivo.
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Academic Article
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A robust in vivo model for B cell precursor acute lymphoblastic leukemia.
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Academic Article
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The graft-versus-tumor effect in pediatric malignancy.
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Academic Article
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CD34? collection efficiency as a function of blood volumes processed in pediatric autologous peripheral blood stem cell collection.
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Academic Article
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T-cell adoptive immunotherapy for acute lymphoblastic leukemia.
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Academic Article
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Val-boroPro accelerates T cell priming via modulation of dendritic cell trafficking resulting in complete regression of established murine tumors.
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Academic Article
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Pneumatosis cystoides intestinalis with labial crepitus in an infant with acute lymphoblastic leukemia.
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Academic Article
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Challenges and opportunities of allogeneic donor-derived CAR T cells.
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Academic Article
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Sequential loss of tumor surface antigens following chimeric antigen receptor T-cell therapies in diffuse large B-cell lymphoma.
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Academic Article
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Graft-versus-host disease impairs vaccine responses through decreased CD4+ and CD8+ T cell proliferation and increased perforin-mediated CD8+ T cell apoptosis.
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Academic Article
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Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression.
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Academic Article
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Systematic Evaluation of Neurotoxicity in Children and Young Adults Undergoing CD22 Chimeric Antigen Receptor T-Cell Therapy.
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Academic Article
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Chimeric Antigen Receptor T-Cell Therapy.
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Academic Article
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Murine pre-B-cell ALL induces T-cell dysfunction not fully reversed by introduction of a chimeric antigen receptor.
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Academic Article
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Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell.
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Academic Article
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Cytomegalovirus Infection Incidence and Risk Factors Across Diverse Hematopoietic Cell Transplantation Platforms Using a Standardized Monitoring and Treatment Approach: A Comprehensive Evaluation from a Single Institution.
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Academic Article
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T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.
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Grant
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Multispecific targeting incorporating cytokine receptor pathways in high risk pediatric acute leukemias to improve durability of adoptive cell therapy-induced remissions
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Academic Article
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Mechanisms of resistance to CAR T cell therapy.
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Concept
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Cell Plasticity
|
Concept
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Cell- and Tissue-Based Therapy
|
Concept
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Stem Cell Research
|
Concept
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HEK293 Cells
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Concept
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Cell Engineering
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Academic Article
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Chimeric Antigen Receptors Incorporating D Domains Targeting CD123 Direct Potent Mono- and Bi-specific Antitumor Activity of T Cells.
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Academic Article
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Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence.
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Academic Article
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Effect of Cryopreservation on Autologous Chimeric Antigen Receptor T Cell Characteristics.
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Academic Article
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Multi-Specific CAR Targeting to Prevent Antigen Escape.
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Academic Article
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Clonal expansion of CAR T cells harboring lentivector integration in the CBL gene following anti-CD22 CAR T-cell therapy.
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Academic Article
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Disease detection methodologies in relapsed B-cell acute lymphoblastic leukemia: Opportunities for improvement.
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Academic Article
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Serial evaluation of CD19 surface expression in pediatric B-cell malignancies following CD19-targeted therapy.
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Academic Article
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Using erythrocyte tools to enhance CAR T cells.
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Academic Article
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CD4/CD8 T-Cell Selection Affects Chimeric Antigen Receptor (CAR) T-Cell Potency and Toxicity: Updated Results From a Phase I Anti-CD22 CAR T-Cell Trial.
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Academic Article
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Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients.
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Academic Article
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Fatal capillary leak syndrome in a child with acute lymphoblastic leukemia treated with moxetumomab pasudotox for pre-transplant minimal residual disease reduction.
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Academic Article
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Diagnostic approach to the evaluation of myeloid malignancies following CAR T-cell therapy in B-cell acute lymphoblastic leukemia.
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Academic Article
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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune effector cell-related adverse events.
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Academic Article
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Robust Antitumor Activity and Low Cytokine Production by Novel Humanized Anti-CD19 CAR T Cells.
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Academic Article
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Long-Term Follow-Up of CD19-CAR T-Cell Therapy in Children and Young Adults With B-ALL.
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Academic Article
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Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design.
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Academic Article
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Infectious complications of CAR T-cell therapy across novel antigen targets in the first 30 days.
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Academic Article
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Does lineage plasticity enable escape from CAR-T cell therapy? Lessons from MLL-r leukemia.
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Academic Article
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Combining Immunocytokine and Ex Vivo Activated NK Cells as a Platform for Enhancing Graft-Versus-Tumor Effects Against GD2+ Murine Neuroblastoma.
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Academic Article
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Characterization of HLH-like manifestations as a CRS variant in patients receiving CD22 CAR T cells.
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Academic Article
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Corrigendum to : <[Experimental Hematology 2021; 100: 1-11]>.
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Academic Article
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CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial.
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Academic Article
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Efficacy of second CAR-T (CART2) infusion limited by poor CART expansion and antigen modulation.
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Academic Article
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CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR.
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Academic Article
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The CD19neg needle in the haystack.
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Academic Article
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The impact of race, ethnicity, and obesity on CAR T-cell therapy outcomes.
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Academic Article
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Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against FLT3- mutant acute myeloid leukemia and KMT2A-rearranged acute lymphoblastic leukemia.
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Academic Article
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Murine allogeneic CAR T cells integrated before or early after posttransplant cyclophosphamide exert antitumor effects.
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Academic Article
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Digital polymerase chain reaction strategies for accurate and precise detection of vector copy number in chimeric antigen receptor T-cell products.
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Academic Article
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Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice.
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Academic Article
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Chimeric Antigen Receptor T Cells as Salvage Therapy for Post-Chimeric Antigen Receptor T Cell Failure.
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Academic Article
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CD22 CAR T-cell associated hematologic toxicities, endothelial activation and relationship to neurotoxicity.
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Academic Article
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CD4+ CAR T cells - more than helpers.
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Academic Article
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Children's Oncology Group's 2023 blueprint for research: Cellular therapy and stem cell transplantation.
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Academic Article
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FOXP1 and KLF2 reciprocally regulate checkpoints of stem-like to effector transition in CAR T cells.
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Academic Article
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Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia response.
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