 Ian James Cleo Purvis
| Title | Post-Doctoral Fellow |
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| Institution | University of Colorado Denver - Anschutz Medical Campus |
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| Department | SOM-OP General Operations |
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 Research F31EY034794 (PURVIS, IAN J)Sep 1, 2023 - Aug 31, 2026 NIH
In The Loop: Investigating Enhancer-Mediated Regulation of OTX2 During Retinal Development
Role: Principal Investigator |
Bibliographic
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Shishido K, Purvis IJ, Velpula KK, Venkataraman S, Vibhakar R, Asuthkar S. Targeting B7-H3 through EZH2 inhibition in MYC-positive Group 3 medulloblastoma. Oncol Rep. 2023 Jun; 49(6). PMID: 37114557.
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Asuthkar S, Venkataraman S, Avilala J, Shishido K, Vibhakar R, Veo B, Purvis IJ, Guda MR, Velpula KK. SMYD3 Promotes Cell Cycle Progression by Inducing Cyclin D3 Transcription and Stabilizing the Cyclin D1 Protein in Medulloblastoma. Cancers (Basel). 2022 Mar 25; 14(7). PMID: 35406445.
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Purvis IJ, Velpula KK, Guda MR, Nguyen D, Tsung AJ, Asuthkar S. B7-H3 in Medulloblastoma-Derived Exosomes; A Novel Tumorigenic Role. Int J Mol Sci. 2020 Sep 25; 21(19). PMID: 32992699.
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Purvis IJ, Avilala J, Guda MR, Venkataraman S, Vibhakar R, Tsung AJ, Velpula KK, Asuthkar S. Role of MYC-miR-29-B7-H3 in Medulloblastoma Growth and Angiogenesis. J Clin Med. 2019 Aug 02; 8(8). PMID: 31382461.
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Smith WM, Purvis IJ, Bomstad CN, Labak CM, Velpula KK, Tsung AJ, Regan JN, Venkataraman S, Vibhakar R, Asuthkar S. Therapeutic targeting of immune checkpoints with small molecule inhibitors. Am J Transl Res. 2019; 11(2):529-541. PMID: 30899360.
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Tsung AJ, Guda MR, Asuthkar S, Labak CM, Purvis IJ, Lu Y, Jain N, Bach SE, Prasad DVR, Velpula KK. Methylation regulates HEY1 expression in glioblastoma. Oncotarget. 2017 Jul 04; 8(27):44398-44409. PMID: 28574840.
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Castellanos JR, Purvis IJ, Labak CM, Guda MR, Tsung AJ, Velpula KK, Asuthkar S. B7-H3 role in the immune landscape of cancer. Am J Clin Exp Immunol. 2017; 6(4):66-75. PMID: 28695059.
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Lu Y, Labak CM, Jain N, Purvis IJ, Guda MR, Bach SE, Tsung AJ, Asuthkar S, Velpula KK. OTX2 expression contributes to proliferation and progression in Myc-amplified medulloblastoma. Am J Cancer Res. 2017; 7(3):647-656. PMID: 28401018.
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Hosking L, Lumsden S, Lewis K, Yeo A, McCarthy L, Bansal A, Riley J, Purvis I, Xu CF. Detection of genotyping errors by Hardy-Weinberg equilibrium testing. Eur J Hum Genet. 2004 May; 12(5):395-9. PMID: 14872201.
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Danoff TM, Campbell DA, McCarthy LC, Lewis KF, Repasch MH, Saunders AM, Spurr NK, Purvis IJ, Roses AD, Xu CF. A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia. Pharmacogenomics J. 2004; 4(1):49-53. PMID: 14647407.
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Xu CF, Lewis KF, Yeo AJ, McCarthy LC, Maguire MF, Anwar Z, Danoff TM, Roses AD, Purvis IJ. Identification of a pharmacogenetic effect by linkage disequilibrium mapping. Pharmacogenomics J. 2004; 4(6):374-8. PMID: 15303110.
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Hewett D, Samuelsson L, Polding J, Enlund F, Smart D, Cantone K, See CG, Chadha S, Inerot A, Enerback C, Montgomery D, Christodolou C, Robinson P, Matthews P, Plumpton M, Wahlstrom J, Swanbeck G, Martinsson T, Roses A, Riley J, Purvis I. Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map. Genomics. 2002 Mar; 79(3):305-14. PMID: 11863360.
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Hosking LK, Boyd PR, Xu CF, Nissum M, Cantone K, Purvis IJ, Khakhar R, Barnes MR, Liberwirth U, Hagen-Mann K, Ehm MG, Riley JH. Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity. Pharmacogenomics J. 2002; 2(3):165-75. PMID: 12082588.
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Xu CF, Lewis K, Cantone KL, Khan P, Donnelly C, White N, Crocker N, Boyd PR, Zaykin DV, Purvis IJ. Effectiveness of computational methods in haplotype prediction. Hum Genet. 2002 Feb; 110(2):148-56. PMID: 11935321.
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McCarthy LC, Hosford DA, Riley JH, Bird MI, White NJ, Hewett DR, Peroutka SJ, Griffiths LR, Boyd PR, Lea RA, Bhatti SM, Hosking LK, Hood CM, Jones KW, Handley AR, Rallan R, Lewis KF, Yeo AJ, Williams PM, Priest RC, Khan P, Donnelly C, Lumsden SM, O'Sullivan J, See CG, Smart DH, Shaw-Hawkins S, Patel J, Langrish TC, Feniuk W, Knowles RG, Thomas M, Libri V, Montgomery DS, Manasco PK, Xu CF, Dykes C, Humphrey PP, Roses AD, Purvis IJ. Single-nucleotide polymorphism alleles in the insulin receptor gene are associated with typical migraine. Genomics. 2001 Dec; 78(3):135-49. PMID: 11735220.
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Haley TM, Angier SJ, Borthwick AD, Montgomery DS, Purvis IJ, Smart DH, Bessant C, Van Wely C, Hart GJ. Investigation of the covalent modification of the catalytic triad of human cytomegalovirus protease by pseudo-reversible beta-lactam inhibitors and a peptide chloromethylketone. J Mass Spectrom. 1998 Dec; 33(12):1246-55. PMID: 9875526.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 1998 | 1 | | 2001 | 2 | | 2002 | 2 | | 2004 | 3 | | 2017 | 3 | | 2019 | 2 | | 2020 | 1 | | 2022 | 1 | | 2023 | 1 |
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