Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53.

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Flt3 Y591 duplication

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Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53.

Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT. Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53. Blood. 2007 Mar 15; 109(6):2589-96.

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subject areas

Cells, Cultured
DNA Damage
Electrophoresis, Gel, Two-Dimensional
fms-Like Tyrosine Kinase 3
Gene Expression
Gene Expression Profiling
Gene Expression Regulation, Leukemic
Humans
Leukemia, Myeloid, Acute
Mutation
Phosphorylation
Protein Isoforms
Proto-Oncogene Proteins c-bcl-2
Signal Transduction
Tumor Suppressor Protein p53
Tyrosine

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Jonathan Irish

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