Factor IX New London: substitution of proline for glutamine at position 50 causes severe hemophilia B.
Lozier JN, Monroe DM, Stanfield-Oakley S, Lin SW, Smith KJ, Roberts HR, High KA. Factor IX New London: substitution of proline for glutamine at position 50 causes severe hemophilia B. Blood. 1990 Mar 01; 75(5):1097-104.