 Karen Adell Lewis
| Title | Affiliate |
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| Institution | University of Colorado Boulder |
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| Department | Biofrontiers Institute |
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 Research T32GM154636 (WHITTEN, STEVEN T)Aug 1, 2024 - Jul 31, 2029 NIH
Texas Doctoral Bridge Program
Role: Co-Principal Investigator |
| T34GM136483 (LEWIS, KAREN ADELL)Apr 1, 2021 - Mar 31, 2026 NIH
U-RISE at Texas State University
Role: Principal Investigator |
| R15GM119096 (LEWIS, KAREN ADELL)May 1, 2016 - Aug 31, 2022 NIH
Molecular Mechanisms of the Posttranscriptional Regulator LARP6
Role: Principal Investigator |
| F32GM093528 (LEWIS, KAREN ADELL)Jun 1, 2011 - May 31, 2013 NIH
In Vitro Reconstitution and Biochemical Characterization of Yeast Telomerase
Role: Principal Investigator |
Bibliographic
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Lewis EM, Becker O, Symons AN, LaCoss C, Baclig AJ, Guzman A, Sanders C, Gonzalez L, Warner LR, Lewis KA. The LARP6 La module from Tetrabaena socialis reveals structural and functional differences from plant and animal LARP6 homologues. RNA Biol. 2025 Dec; 22(1):1-9. PMID: 40181506.
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Cameron B, Torres-Hernandez L, Montague VL, Lewis KA, Smith H, Fox J, Guo X, Kalb RG, George L. Titin is a nucleolar protein in neurons. Res Sq. 2024 Mar 04. PMID: 38496572.
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Wilson C, Lewis KA, Fitzkee NC, Hough LE, Whitten ST. ParSe 2.0: A web tool to identify drivers of protein phase separation at the proteome level. Protein Sci. 2023 09; 32(9):e4756. PMID: 37574757.
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Ibrahim AY, Khaodeuanepheng NP, Amarasekara DL, Correia JJ, Lewis KA, Fitzkee NC, Hough LE, Whitten ST. Intrinsically disordered regions that drive phase separation form a robustly distinct protein class. J Biol Chem. 2023 01; 299(1):102801. PMID: 36528065.
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Paiz EA, Lewis KA, Whitten ST. Structural and Energetic Characterization of the Denatured State from the Perspectives of Peptides, the Coil Library, and Intrinsically Disordered Proteins. Molecules. 2021 Jan 26; 26(3). PMID: 33530506.
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Dock-Bregeon AC, Lewis KA, Conte MR. The La-related proteins: structures and interactions of a versatile superfamily of RNA-binding proteins. RNA Biol. 2021 02; 18(2):178-193. PMID: 31752575.
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Lewis KA, Altschuler SE, Wuttke DS. Measuring Low-Picomolar Apparent Binding Affinities by Minigel Electrophoretic Mobility Shift. Methods Mol Biol. 2019; 1855:341-354. PMID: 30426430.
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Ream JA, Lewis LK, Lewis KA. Horizontal Agarose Gel Mobility Shift Assay for Protein-RNA Complexes. Methods Mol Biol. 2019; 1855:363-370. PMID: 30426432.
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Castro JM, Horn DA, Pu X, Lewis KA. Recombinant expression and purification of the RNA-binding LARP6 proteins from fish genetic model organisms. Protein Expr Purif. 2017 Jun; 134:147-153. PMID: 28400296.
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Villarreal MA, Biediger NM, Bonner NA, Miller JN, Zepeda SK, Ricard BJ, Garc?a DM, Lewis KA. Determining Zebrafish Epitope Reactivity to Commercially Available Antibodies. Zebrafish. 2017 08; 14(4):387-389. PMID: 28318435.
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Ream JA, Lewis LK, Lewis KA. Rapid agarose gel electrophoretic mobility shift assay for quantitating protein: RNA interactions. Anal Biochem. 2016 10 15; 511:36-41. PMID: 27495142.
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Lau HT, Lewis KA, Ong SE. Quantifying in vivo, site-specific changes in protein methylation with SILAC. Methods Mol Biol. 2014; 1188:161-75. PMID: 25059611.
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Lewis KA, Pfaff DA, Earley JN, Altschuler SE, Wuttke DS. The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain. Nucleic Acids Res. 2014 Jan; 42(1):475-84. PMID: 24057216.
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Altschuler SE, Lewis KA, Wuttke DS. Practical strategies for the evaluation of high-affinity protein/nucleic acid interactions. J Nucleic Acids Investig. 2013 Jan 01; 4(1):19-28. PMID: 25197549.
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Lewis KA, Wuttke DS. Telomerase and telomere-associated proteins: structural insights into mechanism and evolution. Structure. 2012 Jan 11; 20(1):28-39. PMID: 22244753.
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Lewis KA, Su Y, Jou O, Ritchie C, Foong C, Hynan LS, White CL, Thomas PJ, Hatanpaa KJ. Abnormal neurites containing C-terminally truncated alpha-synuclein are present in Alzheimer's disease without conventional Lewy body pathology. Am J Pathol. 2010 Dec; 177(6):3037-50. PMID: 21056999.
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Lewis KA, Yaeger A, DeMartino GN, Thomas PJ. Accelerated formation of alpha-synuclein oligomers by concerted action of the 20S proteasome and familial Parkinson mutations. J Bioenerg Biomembr. 2010 Feb; 42(1):85-95. PMID: 20148295.
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Chen Z, Lewis KA, Shultzaberger RK, Lyakhov IG, Zheng M, Doan B, Storz G, Schneider TD. Discovery of Fur binding site clusters in Escherichia coli by information theory models. Nucleic Acids Res. 2007; 35(20):6762-77. PMID: 17921503.
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Shultzaberger RK, Chen Z, Lewis KA, Schneider TD. Anatomy of Escherichia coli sigma70 promoters. Nucleic Acids Res. 2007; 35(3):771-88. PMID: 17189297.
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Liu CW, Giasson BI, Lewis KA, Lee VM, Demartino GN, Thomas PJ. A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease. J Biol Chem. 2005 Jun 17; 280(24):22670-8. PMID: 15840579.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2005 | 1 | | 2006 | 1 | | 2007 | 1 | | 2010 | 2 | | 2012 | 1 | | 2013 | 2 | | 2014 | 1 | | 2016 | 1 | | 2017 | 2 | | 2019 | 3 | | 2021 | 1 | | 2022 | 1 | | 2023 | 1 | | 2024 | 1 | | 2025 | 1 |
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