 Anthramycin
"Anthramycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad-spectrum spectrum antineoplastic antibiotic isolated from Streptomyces refuineus var. thermotolerans. It has low toxicity, some activity against Trichomonas and Endamoeba, and inhibits RNA and DNA synthesis. It binds irreversibly to DNA.
| Descriptor ID |
D000876
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| MeSH Number(s) |
D03.633.100.079.080.070.050 D03.633.300.060
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Anthramycin".
Below are MeSH descriptors whose meaning is more specific than "Anthramycin".
This graph shows the total number of publications written about "Anthramycin" by people in this website by year, and whether "Anthramycin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Anthramycin" by people in Profiles.
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Phelan VV, Du Y, McLean JA, Bachmann BO. Adenylation enzyme characterization using gamma -(18)O(4)-ATP pyrophosphate exchange. Chem Biol. 2009 May 29; 16(5):473-8.
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Hu Y, Phelan VV, Farnet CM, Zazopoulos E, Bachmann BO. Reassembly of anthramycin biosynthetic gene cluster by using recombinogenic cassettes. Chembiochem. 2008 Jul 02; 9(10):1603-8.
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Hu Y, Phelan V, Ntai I, Farnet CM, Zazopoulos E, Bachmann BO. Benzodiazepine biosynthesis in Streptomyces refuineus. Chem Biol. 2007 Jun; 14(6):691-701.
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