Flumazenil
"Flumazenil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
Descriptor ID |
D005442
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MeSH Number(s) |
D03.633.100.079.080.070.305
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Flumazenil".
Below are MeSH descriptors whose meaning is more specific than "Flumazenil".
This graph shows the total number of publications written about "Flumazenil" by people in this website by year, and whether "Flumazenil" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 2011 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2016 | 0 | 2 | 2 | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Flumazenil" by people in Profiles.
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Schelp SA, Brodnik ZD, Rakowski DR, Pultorak KJ, Sambells AT, Espa?a RA, Oleson EB. Diazepam Concurrently Increases the Frequency and Decreases the Amplitude of Transient Dopamine Release Events in the Nucleus Accumbens. J Pharmacol Exp Ther. 2018 01; 364(1):145-155.
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Pomares FB, Funck T, Feier NA, Roy S, Daigle-Martel A, Ceko M, Narayanan S, Araujo D, Thiel A, Stikov N, Fitzcharles MA, Schweinhardt P. Histological Underpinnings of Grey Matter Changes in Fibromyalgia Investigated Using Multimodal Brain Imaging. J Neurosci. 2017 02 01; 37(5):1090-1101.
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Puening SE, Wilson MP, Nordstrom K. Psychiatric Emergencies for Clinicians: Emergency Department Management of Benzodiazepine Withdrawal. J Emerg Med. 2017 01; 52(1):66-69.
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Schacht JP, Anton RF, Randall PK, Li X, Henderson S, Myrick H. Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics. Psychopharmacology (Berl). 2013 Jun; 227(4):627-37.
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Divljakovic J, Milic M, Namjoshi OA, Tiruveedhula VV, Timic T, Cook JM, Savic MM. ?CCT, an antagonist selective for a(1)GABA(A) receptors, reverses diazepam withdrawal-induced anxiety in rats. Brain Res Bull. 2013 Feb; 91:1-7.
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Milic M, Divljakovic J, Rallapalli S, van Linn ML, Timic T, Cook JM, Savic MM. The role of a1 and a5 subunit-containing GABAA receptors in motor impairment induced by benzodiazepines in rats. Behav Pharmacol. 2012 Apr; 23(2):191-7.
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Schacht JP, Randall PK, Waid LR, Baros AM, Latham PK, Wright TM, Myrick H, Anton RF. Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence. Alcohol Clin Exp Res. 2011 Nov; 35(11):2030-8.
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Maier SF, Grahn RE, Maswood S, Watkins LR. The benzodiazepine receptor antagonists flumazenil and CGS8216 block the enhancement of fear conditioning and interference with escape behavior produced by inescapable shock. Psychopharmacology (Berl). 1995 Sep; 121(2):250-8.
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Short KR, Maier SF. Stressor controllability, social interaction, and benzodiazepine systems. Pharmacol Biochem Behav. 1993 Aug; 45(4):827-35.
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Melchior CL, Garrett KM, Tabakoff B. A benzodiazepine antagonist action of CL 218,872. Life Sci. 1984 May 28; 34(22):2201-6.
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