Spiperone
"Spiperone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
Descriptor ID |
D013134
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MeSH Number(s) |
D02.455.426.779.800 D02.522.352.800 D04.711.800
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spiperone".
Below are MeSH descriptors whose meaning is more specific than "Spiperone".
This graph shows the total number of publications written about "Spiperone" by people in this website by year, and whether "Spiperone" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spiperone" by people in Profiles.
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Liang L, MacDonald K, Schwiebert EM, Zeitlin PL, Guggino WB. Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway. Am J Physiol Cell Physiol. 2009 Jan; 296(1):C131-41.
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Hawkins MF, Uzelac SM, Hearn JK, Baumeister AA. Effects of selective serotonin2 ligands on behaviors evoked by stress in the rat. Pharmacol Biochem Behav. 2008 Oct; 90(4):632-9.
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MacLennan AJ, Pelleymounter MA, Atmadja S, Jakubovic A, Maier SF, Fibiger HC. D2 dopamine receptors in the rat prefrontal cortex: characterization and alteration by stress. Brain Res. 1989 Jan 16; 477(1-2):300-7.
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Tabakoff B, Hoffman PL. Development of functional dependence on ethanol in dopaminergic systems. J Pharmacol Exp Ther. 1979 Feb; 208(2):216-22.