 Secretory Component
"Secretory Component" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extracellular moiety of the POLYMERIC IMMUNOGLOBULIN RECEPTOR found alone or complexed with IGA or IGM, in a variety of external secretions (tears, bile, colostrum.) Secretory component is derived by proteolytic cleavage of the receptor during transcytosis. When immunoglobulins IgA and IgM are bound to the receptor, during their transcytosis secretory component becomes covalently attached to them generating SECRETORY IMMUNOGLOBULIN A or secretory IMMUNOGLOBULIN M.
| Descriptor ID |
D012635
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| MeSH Number(s) |
D12.776.124.486.485.114.619.026.030.500 D12.776.124.486.485.705.875 D12.776.124.790.651.114.619.026.030.500 D12.776.124.790.651.705.875 D12.776.377.715.548.114.619.026.030.500 D12.776.377.715.548.705.875
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Below are MeSH descriptors whose meaning is more general than "Secretory Component".
Below are MeSH descriptors whose meaning is more specific than "Secretory Component".
This graph shows the total number of publications written about "Secretory Component" by people in this website by year, and whether "Secretory Component" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Secretory Component" by people in Profiles.
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King SJ, Hippe KR, Gould JM, Bae D, Peterson S, Cline RT, Fasching C, Janoff EN, Weiser JN. Phase variable desialylation of host proteins that bind to Streptococcus pneumoniae in vivo and protect the airway. Mol Microbiol. 2004 Oct; 54(1):159-71.
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Ahnen DJ, Kinoshita K, Nakane PK, Brown WR. Differential expression carcinoembryonic antigen and secretory component during colonic epithelial cell differentiation and in colonic carcinomas. Gastroenterology. 1987 Dec; 93(6):1330-8.
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Cambier JC, Butler JE. Two immunochemically and physicochemically distinct secretory components from rat exocrine secretion. J Immunol. 1976 Apr; 116(4):994-9.
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