 Immunoglobulin J-Chains
"Immunoglobulin J-Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 15 kD "joining" peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light and heavy chains.
| Descriptor ID |
D007144
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| MeSH Number(s) |
D12.776.124.486.485.705.625 D12.776.124.790.651.705.625 D12.776.377.715.548.705.625
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| Concept/Terms |
Immunoglobulin J-Chains- Immunoglobulin J-Chains
- Immunoglobulin J Chains
- J-Chains, Immunoglobulin
- J Chains, Immunoglobulin
- Immunoglobulin J-Peptide
- Immunoglobulin J Peptide
- J-Peptide, Immunoglobulin
- Ig J-Peptide
- Ig J Peptide
- J-Peptide, Ig
- Immunoglobulin J Polypeptide
- J Polypeptide, Immunoglobulin
- Polypeptide, Immunoglobulin J
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin J-Chains".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin J-Chains".
This graph shows the total number of publications written about "Immunoglobulin J-Chains" by people in this website by year, and whether "Immunoglobulin J-Chains" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin J-Chains" by people in Profiles.
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Bowler RP, Reisdorph N, Reisdorph R, Abraham E. Alterations in the human lung proteome with lipopolysaccharide. BMC Pulm Med. 2009 May 11; 9:20.
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Reardon CL, Hu LJ, Yin X, Born WK, Arden B, O'Brien R. A new mechanism for generating TCR diversity: A TCR Jalpha-like gene that inserts partial nucleotide sequences in a D-gene manner. Mol Immunol. 2007 Feb; 44(5):906-15.
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Walling DM, Andritsos LA, Etienne W, Payne DA, Aronson JF, Flaitz CM, Nichols CM. Molecular markers of clonality and identity in Epstein-Barr virus-associated B-cell lymphoproliferative disease. J Med Virol. 2004 Sep; 74(1):94-101.
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Hsi ED, Tubbs RR, Lovell MA, Braziel RM, Gulley ML. Detection of bcl-2/J(H) translocation by polymerase chain reaction: a summary of the experience of the Molecular Oncology Survey of the College of American Pathologist. Arch Pathol Lab Med. 2002 Aug; 126(8):902-8.
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Epstein R, Roehm N, Marrack P, Kappler J, Davis M, Hedrick S, Cohn M. Genetic markers of the antigen-specific T cell receptor locus. J Exp Med. 1985 May 01; 161(5):1219-24.
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