 Immunoglobulin A
"Immunoglobulin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions.
| Descriptor ID |
D007070
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| MeSH Number(s) |
D12.776.124.486.485.114.619.026 D12.776.124.790.651.114.619.026 D12.776.377.715.548.114.619.026
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin A".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin A".
This graph shows the total number of publications written about "Immunoglobulin A" by people in this website by year, and whether "Immunoglobulin A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 4 | 1 | 5 | | 1996 | 1 | 0 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 0 | 2 | 2 | | 2001 | 0 | 2 | 2 | | 2002 | 1 | 2 | 3 | | 2003 | 1 | 2 | 3 | | 2004 | 2 | 3 | 5 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 3 | 3 | | 2007 | 2 | 2 | 4 | | 2008 | 0 | 4 | 4 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 3 | 3 | | 2012 | 0 | 1 | 1 | | 2013 | 2 | 1 | 3 | | 2014 | 2 | 0 | 2 | | 2015 | 0 | 5 | 5 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 6 | 7 | | 2018 | 0 | 3 | 3 | | 2019 | 4 | 1 | 5 | | 2020 | 2 | 1 | 3 | | 2021 | 3 | 5 | 8 | | 2022 | 4 | 6 | 10 | | 2023 | 0 | 6 | 6 | | 2024 | 0 | 1 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin A" by people in Profiles.
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Olm MR, Spencer SP, Takeuchi T, Silva EL, Sonnenburg JL. Metagenomic immunoglobulin sequencing reveals IgA coating of microbial strains in the healthy human gut. Nat Microbiol. 2025 Jan; 10(1):112-125.
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Stahl MG, Pan Z, Germone M, Nagle S, Mehta P, Shull M, Griffith I, Shuler B, Hoffenberg E, Taki I, Geno-Rasmussen C, Rewers MJ, Norris JM, Liu E. One-Year Outcomes Among Children Identified With Celiac Disease Through a Mass Screening Program. Clin Gastroenterol Hepatol. 2025 Jun; 23(7):1135-1142.
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Novis CL, Wahl E, Camacho E, Aure MA, Mahler M, Nandakumar V. Performance Assessment of a Novel Multianalyte Methodology for Celiac Disease Biomarker Detection and Evaluation of the Serology-Alone Criteria for Biopsy-Free Diagnosis. Arch Pathol Lab Med. 2023 12 01; 147(12):1422-1430.
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Giles JB, Rollin J, Martinez KL, Selleng K, Thiele T, Pouplard C, Sheppard JI, Heddle NM, Phillips EJ, Roden DM, Gruel Y, Warkentin TE, Greinacher A, Karnes JH. Laboratory and demographic predictors of functional assay positive status in suspected heparin-induced thrombocytopenia: A multicenter retrospective cohort study. Thromb Res. 2023 09; 229:198-208.
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Stone HK, Mitsnefes M, Dickinson K, Burrows EK, Razzaghi H, Luna IY, Gluck CA, Dixon BP, Dharnidharka VR, Smoyer WE, Somers MJ, Flynn JT, Furth SL, Bailey C, Forrest CB, Denburg M, Nehus E. Clinical course and management of children with IgA vasculitis with nephritis. Pediatr Nephrol. 2023 11; 38(11):3721-3733.
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Seifert JA, Bemis EA, Ramsden K, Lowell C, Polinski K, Feser M, Fleischer C, Demoruelle MK, Buckner J, Gregersen PK, Keating RM, Mikuls TR, O'Dell JR, Weisman MH, Deane KD, Norris JM, Steere AC, Holers VM. Association of Antibodies to Prevotella copri in Anti-Cyclic Citrullinated Peptide-Positive Individuals At Risk of Developing Rheumatoid Arthritis and in Patients With Early or Established Rheumatoid Arthritis. Arthritis Rheumatol. 2023 04; 75(4):507-516.
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Lee JA, Mikuls TR, Deane KD, Sayles HR, Thiele GM, Edison JD, Wagner BD, Feser ML, Moss LK, Kelmenson LB, Robinson WH, Payne JB. Serum antibodies to periodontal pathogens prior to rheumatoid arthritis diagnosis: A case-control study. Semin Arthritis Rheum. 2023 04; 59:152176.
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Shimizu M, Irabu H, Shimbo A, Kaneko S, Mori M. Monthly intravenous immunoglobulin for refractory intestinal IgA vasculitis. Pediatr Int. 2023 01; 65(1):e15470.
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Liu EG, Zhang B, Martin V, Anthonypillai J, Kraft M, Grishin A, Grishina G, Catanzaro JR, Chinthrajah S, Sindher T, Manohar M, Quake AZ, Nadeau K, Burks AW, Kim EH, Kulis MD, Henning AK, Jones SM, Leung DYM, Sicherer SH, Wood RA, Yuan Q, Shreffler W, Sampson H, Shabanova V, Eisenbarth SC. Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens. Sci Transl Med. 2022 11 16; 14(671):eabq0599.
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Redzic JS, Rahkola J, Tran N, Holyoak T, Lee E, Mart?n-Galiano AJ, Meyer N, Zheng H, Eisenmesser E. A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases. Commun Biol. 2022 11 07; 5(1):1190.
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