 Receptors, Neurokinin-1
"Receptors, Neurokinin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of cell surface receptors for TACHYKININS with a preference for SUBSTANCE P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.
| Descriptor ID |
D018040
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| MeSH Number(s) |
D12.776.543.750.695.862.500 D12.776.543.750.720.600.830.500 D12.776.543.750.750.555.830.500
|
| Concept/Terms |
Receptors, Neurokinin-1- Receptors, Neurokinin-1
- Receptors, Neurokinin 1
- Substance P Receptors
- Receptors, Substance P
- P Receptors, Substance
- NK-1 Receptor
- NK 1 Receptor
- Receptor, NK-1
- Receptors, NK-1
- Receptors, NK 1
- NK-1 Receptors
- NK 1 Receptors
- Tachykinin Receptor 1
- Neurokinin-1 Receptors
- Neurokinin 1 Receptors
- Receptors, SP-P
- Receptors, SP P
- SP-P Receptor
- Receptor, SP-P
- SP P Receptor
- SP-P Receptors
- SP P Receptors
- Substance-P Receptor
- Receptor, Substance-P
- Substance P Receptor
- P Receptor, Substance
- Receptor, Substance P
- Neurokinin-1 Receptor
- Neurokinin 1 Receptor
- Receptor, Neurokinin-1
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Below are MeSH descriptors whose meaning is more general than "Receptors, Neurokinin-1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Tachykinin [D12.776.543.750.695.862]
- Receptors, Neurokinin-1 [D12.776.543.750.695.862.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Tachykinin [D12.776.543.750.720.600.830]
- Receptors, Neurokinin-1 [D12.776.543.750.720.600.830.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Tachykinin [D12.776.543.750.750.555.830]
- Receptors, Neurokinin-1 [D12.776.543.750.750.555.830.500]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Neurokinin-1".
This graph shows the total number of publications written about "Receptors, Neurokinin-1" by people in this website by year, and whether "Receptors, Neurokinin-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 0 | 1 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 2 | 0 | 2 | | 2014 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Neurokinin-1" by people in Profiles.
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Decker Ramirez EB, Arnold ME, Schank JR. Vicarious defeat stress induces increased alcohol consumption in female mice: Role of neurokinin-1 receptor and interleukin-6. Addict Biol. 2024 01; 29(1):e13357.
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Decker Ramirez EB, Arnold ME, McConnell KT, Solomon MG, Amico KN, Schank JR. The effects of lipopolysaccharide exposure on social interaction, cytokine expression, and alcohol consumption in male and female mice. Physiol Behav. 2023 06 01; 265:114159.
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Bubak AN, Como CN, Blackmon AM, Frietze S, Mescher T, Jones D, Cohrs RJ, Paucek P, Baird NL, Nagel MA. Varicella Zoster Virus Induces Nuclear Translocation of the Neurokinin-1 Receptor, Promoting Lamellipodia Formation and Viral Spread in Spinal Astrocytes. J Infect Dis. 2018 09 08; 218(8):1324-1335.
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Saunders CJ, Christensen M, Finger TE, Tizzano M. Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammation. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):6075-80.
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Spitsin S, Tuluc F, Meshki J, Ping Lai J, Tustin Iii R, Douglas SD. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013; 20(5):247-55.
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Schwartz L, Spitsin SV, Meshki J, Tuluc F, Douglas SD, Wolfe JH. Substance P enhances HIV-1 infection in human fetal brain cell cultures expressing full-length neurokinin-1 receptor. J Neurovirol. 2013 Jun; 19(3):219-27.
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Blaine S, Claus E, Harlaar N, Hutchison K. TACR1 genotypes predict fMRI response to alcohol cues and level of alcohol dependence. Alcohol Clin Exp Res. 2013 Jan; 37 Suppl 1:E125-30.
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Chen P, Douglas SD, Meshki J, Tuluc F. Neurokinin 1 receptor mediates membrane blebbing and sheer stress-induced microparticle formation in HEK293 cells. PLoS One. 2012; 7(9):e45322.
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Manak MM, Moshkoff DA, Nguyen LT, Meshki J, Tebas P, Tuluc F, Douglas SD. Anti-HIV-1 activity of the neurokinin-1 receptor antagonist aprepitant and synergistic interactions with other antiretrovirals. AIDS. 2010 Nov 27; 24(18):2789-96.
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Ablin JN, Bar-Shira A, Yaron M, Orr-Urtreger A. Candidate-gene approach in fibromyalgia syndrome: association analysis of the genes encoding substance P receptor, dopamine transporter and alpha1-antitrypsin. Clin Exp Rheumatol. 2009 Sep-Oct; 27(5 Suppl 56):S33-8.
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