 Metallothionein
"Metallothionein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver. It is rich in cysteinyl residues and contains no aromatic amino acids. Metallothionein shows high affinity for bivalent heavy metals.
| Descriptor ID |
D008668
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| MeSH Number(s) |
D12.776.556.670
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Metallothionein".
Below are MeSH descriptors whose meaning is more specific than "Metallothionein".
This graph shows the total number of publications written about "Metallothionein" by people in this website by year, and whether "Metallothionein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 2 | 3 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 2 | 0 | 2 | | 2015 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Metallothionein" by people in Profiles.
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McDonald S, Hassell K, Cresswell T. Effect of short-term dietary exposure on metal assimilation and metallothionein induction in the estuarine fish Pseudogobius sp. Sci Total Environ. 2021 Jun 10; 772:145042.
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Evans JG, Todorovic SM. Redox and trace metal regulation of ion channels in the pain pathway. Biochem J. 2015 Sep 15; 470(3):275-80.
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Morphew MK, O'Toole ET, Page CL, Pagratis M, Meehl J, Giddings T, Gardner JM, Ackerson C, Jaspersen SL, Winey M, Hoenger A, McIntosh JR. Metallothionein as a clonable tag for protein localization by electron microscopy of cells. J Microsc. 2015 Oct; 260(1):20-9.
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Gonzalez-Iglesias H, Alvarez L, Garc?a M, Petrash C, Sanz-Medel A, Coca-Prados M. Metallothioneins (MTs) in the human eye: a perspective article on the zinc-MT redox cycle. Metallomics. 2014 Feb; 6(2):201-8.
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Bouchet-Marquis C, Pagratis M, Kirmse R, Hoenger A. Metallothionein as a clonable high-density marker for cryo-electron microscopy. J Struct Biol. 2012 Jan; 177(1):119-27.
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Nagy KL, Manceau A, Gasper JD, Ryan JN, Aiken GR. Metallothionein-like multinuclear clusters of mercury(II) and sulfur in peat. Environ Sci Technol. 2011 Sep 01; 45(17):7298-306.
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Huang YC, Li Z, Carter JD, Soukup JM, Schwartz DA, Yang IV. Fine ambient particles induce oxidative stress and metal binding genes in human alveolar macrophages. Am J Respir Cell Mol Biol. 2009 Nov; 41(5):544-52.
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Lynes MA, Fontenot AP, Lawrence DA, Rosenspire AJ, Pollard KM. Gene expression influences on metal immunomodulation. Toxicol Appl Pharmacol. 2006 Jan 01; 210(1-2):9-16.
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Matzuk MM, DeMayo FJ, Hadsell LA, Kumar TR. Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice. Biol Reprod. 2003 Jul; 69(1):338-46.
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Cipriano SC, Chen L, Kumar TR, Matzuk MM. Follistatin is a modulator of gonadal tumor progression and the activin-induced wasting syndrome in inhibin-deficient mice. Endocrinology. 2000 Jul; 141(7):2319-27.
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