beta-Mannosidase
"beta-Mannosidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS.
| Descriptor ID |
D044902
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| MeSH Number(s) |
D08.811.277.450.625.750
|
| Concept/Terms |
beta-Mannosidase- beta-Mannosidase
- beta Mannosidase
- beta-Mannanase
- beta Mannanase
- manA protein (beta-Mannosidase)
- beta-D-Mannosidase
- beta D Mannosidase
|
Below are MeSH descriptors whose meaning is more general than "beta-Mannosidase".
Below are MeSH descriptors whose meaning is more specific than "beta-Mannosidase".
This graph shows the total number of publications written about "beta-Mannosidase" by people in this website by year, and whether "beta-Mannosidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Mannosidase" by people in Profiles.
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Briganti L, Manzine LR, de Mello Capetti CC, de Ara?jo EA, de Oliveira Arnoldi Pellegrini V, Guimaraes FEG, de Oliveira Neto M, Polikarpov I. Unravelling biochemical and structural features of Bacillus licheniformis GH5 mannanase using site-directed mutagenesis and high-resolution protein crystallography studies. Int J Biol Macromol. 2024 Aug; 274(Pt 2):133182.
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Tjoa S, Wenger DA, Fennessey PV. Quantitative analysis of disaccharides in the urine of beta-mannosidosis patients. J Inherit Metab Dis. 1990; 13(2):187-94.
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Wenger DA, Sujansky E, Fennessey PV, Thompson JN. Human beta-mannosidase deficiency. N Engl J Med. 1986 Nov 06; 315(19):1201-5.