 Giant Cell Tumor of Bone
"Giant Cell Tumor of Bone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)
| Descriptor ID |
D018212
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| MeSH Number(s) |
C04.557.450.565.380.380 C04.557.450.565.575.420
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Giant Cell Tumor of Bone".
Below are MeSH descriptors whose meaning is more specific than "Giant Cell Tumor of Bone".
This graph shows the total number of publications written about "Giant Cell Tumor of Bone" by people in this website by year, and whether "Giant Cell Tumor of Bone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2004 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Giant Cell Tumor of Bone" by people in Profiles.
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Jeys LM, Botello E, Boyle R, Ebeid W, Hilton T, Houdek MT, Hosking K, Kurisunkal VJ, Laubscher M, Morris GV, Puri A, Ruggieri P, Laitinen MK, Abdul Bari Y, Abood A, Abraham JA, Acosta Marin M, Agarwal M, Agarwal R, Aguirre M, Ajit Singh V, Akiyama T, Al Farii H, Alaqeel M, Alaseem A, Aldosari O, Alexander K, Alfaro P, Aljuhani W, Allison DC, Almashahedi M, Alotaibi A, Alpan B, Alshaygy IS, Althunayan T, Andreani L, Andreou D, Andriandi A, Annabelle L, Aponte-Tinao L, Ardelt M, Armas S, Aston W, Aycan OE, Baad-Hansen T, Baeza P, Baird C, Balach T, Banse X, Barriga J, Barry J, Basile G, Bastoni S, Basuki MH, Bauer HC, Baydar S, Bayliss L, Becker R, Bedi A, Benevenia J, Bengoa F, Berger C, Bernthal N, Binitie O, Bird J, Bobseit A, Bodian C, Boffano M, Bonilla Huertas P, Bramer J, Broadhead M, Broekhuis D, Broida SE, Brown D, Bruschi A, Budny T, Buist M, Burke Z, Busse T, Cabrolier J, Calvo-Haro JA, Campanacci DA, Cardoso R, Carey Smith R, Carrasco MG, Casales N, Castan A, Ceballos O, Chan CM, Chan L, Chang LZ, Charoenlap C, Chaustre Florez JF, Chin J, Choong P, Chrobok A, Chung YG, Ciechanowicz D, Clara-Altamirano MA, Consuegra Guzman LA, Cornu O, Coubeau L, Courtot L, Crawford B, Cribb G, Cuervo-Lozano CE, Dammerer D, de la Rosa P, de Lima Corvino D, De Paolis M, De Santos de la Fuente FJ, de Vaal M, Deisenhofer JM, Delgado Obando J, Demir E, Deo S, Deventer N, Di Bella C, Dierselhuis E, Docquier PL, Domson G, Donati DM, Doshi A, Duivenvoorden MJC, Duran-Ciarrochi R, Dürr HR, Ehlers PJ, El Ghoneimy AM, El Motassime A, Eloi Pinto FF, Endo M, Epstein G, Eralp L, Etaiwi M, Eward W, Fabbri N, Faimali M, Farman U, Farooq A, Farooque K, Farris C, Ferguson P, Ferreira N, Fiorenza F, Flint M, Forsberg JA, Franks D, Freitas JP, Fuchs B, Fujiwara T, Funovics PT, Fuzy E, Galli Serra M, Gamie Z, Garcia-Carrasco M, García-Huidobro G, Gaston CL, Gazendam A, Georges B, Ghert M, Ghosh KM, Giardina FL, Gibbs CP, Golovina Y, Gomez Mier LC, Gomez-Mascard A, Gomez-Sierra MA, González-Browne C, Gonzalez-Saldivar J, González-Motta A, Gortzak Y, Gosheger G, Gouin F, Goulding K, Gracia I, Graydon A, Green N, Griffin A, Guedes A, Gulia A, Gupta S, Guzman M, Hardes J, Hasan YO, Hashim AM, Havard H, Haydon R, Hegde P, Hernandez Lopez A, Herrera D, Hesham A, Hesla A, Hess M, Hirschmann A, Hobusch G, Hohensteiner A, Hongsaprabhas C, Hornicek F, Hsu M, Idowu OK, Idulhaq M, Igbinoba B, Ippolito JA, Iwata S, Jagiello J, Johan MP, Johnson L, Johnston A, Joo MW, Joyce D, Jung B, Jungels C, Jutte P, Jutte W, Jääskeläinen AS, Kaldas K, Kapanci B, Karaca MO, Kawai A, Kemp A, Khal AA, Khan Z, Khan ZA, Khaouam N, Kim HS, Klopper S, Kobayashi E, Kobayashi H, Kontogeorgakos V, Kotrych D, Krebbekx GGJ, Krishnamurthy AV, Kunisada T, Kyte R, Lacroix V, Lazarides A, Le Nail LR, Lee FY, Lee J, Lee M, Legosz P, Lehner B, Leithner A, Leone G, Letson D, Lewis VO, Li B, Liikanen H, Lin P, Linda Z, Lindsay S, Lozano Calderon S, Lutomia Lumbasi M, Macdonald J, Machado P, Majirija E, Malina M, Malyk R, Marais L, Mascard E, Mattei JC, McCullough L, McMahon S, Medellin Rincon MR, Mediavilla Santos L, Meijer D, Meijer JG, Miller B, Molloy A, Moriel Garcesco DJ, Morris CD, Morse-Sanyal A, Mottard S, Mthethwa PG, Muñoz-Montecinos C, Murcia M, Müller M, Nakayama R, Narhari P, Nasar A, Nayak P, Neugebauer J, Nieminen J, Ntombela P, Nystrom L, O'Reilly-Harbidge S, O'Toole G, Ogura K, Oktayana MD, Oliveira V, Olivier A, Olson D, Olusunmade O, Omar M, Omran Hasan Y, Ortiz-Cruz EJ, Ozaki S, Ozaki T, Ozkan K, Pala E, Palmerini E, Panchwagh Y, Pang G, Papagelopoulos P, Papagelopoulos DP, Paraliticci G, Parizzia W, Parry M, Pate M, Peiró A, Perera J, Petersen MM, Phakathi O, Phimolsarnti R, Phiri T, Pinheiro R, Pinto Santander N, Ploegmakers J, Pollock R, Powell G, Prabowo Y, Pruthi M, Puhaindran M, Quirion J, Quirland C, Rabin E, Rachbauer A, Radhakrishnan S, Raja A, Rajalbandi R, Rajani R, Rajasekaran RB, Rajasekaran S, Rajkovic S, Ramirez MT, Ramkumar DB, Rankin KS, Ras El Abiad A, et al. A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM). Bone Joint J. 2026 Jun 09; 108-B:xxx.
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Chang YC, Stoyanova R, Danilova S, Pretell-Mazzini JA, Kerr DA, Wilky BA, Subhawong T. Radiomics on radiography predicts giant cell tumor histologic response to denosumab. Skeletal Radiol. 2021 Sep; 50(9):1881-1887.
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Kerr DA, Brcic I, Diaz-Perez JA, Shih A, Wilky BA, Pretell-Mazzini J, Subhawong TK, Nielsen GP, Rosenberg AE. Immunohistochemical Characterization of Giant Cell Tumor of Bone Treated With Denosumab: Support for Osteoblastic Differentiation. Am J Surg Pathol. 2021 01; 45(1):93-100.
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Freeman JL, Oushy S, Schowinsky J, Sillau S, Youssef AS. Invasive Giant Cell Tumor of the Lateral Skull Base: A Systematic Review, Meta-Analysis, and Case Illustration. World Neurosurg. 2016 Dec; 96:47-57.
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Kremen TJ, Bernthal NM, Eckardt MA, Eckardt JJ. Giant cell tumor of bone: are we stratifying results appropriately? Clin Orthop Relat Res. 2012 Mar; 470(3):677-83.
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Malek F, Krueger P, Hatmi ZN, Malayeri AA, Faezipour H, O'Donnell RJ. Local control of long bone giant cell tumour using curettage, burring and bone grafting without adjuvant therapy. Int Orthop. 2006 Dec; 30(6):495-8.
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Baisre A, Aisner S, Blacksin M, Benevenia J, Hameed MR. Pathologic quiz case. An 18-year-old man with pain and swelling of the left hand. Chondroblastoma. Arch Pathol Lab Med. 2004 Sep; 128(9):e120-1.
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